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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1976 1
1977 2
1978 3
1979 3
1980 7
1981 5
1982 5
1983 4
1984 3
1985 4
1986 3
1987 8
1988 6
1989 3
1990 13
1991 18
1992 21
1993 58
1994 30
1995 29
1996 37
1997 51
1998 46
1999 77
2000 82
2001 95
2002 83
2003 84
2004 95
2005 107
2006 165
2007 130
2008 130
2009 140
2010 190
2011 180
2012 162
2013 214
2014 207
2015 181
2016 202
2017 217
2018 184
2019 207
2020 272
2021 328
2022 215
2023 186
2024 68

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4,092 results

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Page 1
SF1 and SF2 helicases: family matters.
Fairman-Williams ME, Guenther UP, Jankowsky E. Fairman-Williams ME, et al. Curr Opin Struct Biol. 2010 Jun;20(3):313-24. doi: 10.1016/j.sbi.2010.03.011. Epub 2010 Apr 22. Curr Opin Struct Biol. 2010. PMID: 20456941 Free PMC article. Review.
Helicases of the superfamily (SF) 1 and 2 are involved in virtually all aspects of RNA and DNA metabolism. ...We discuss recent data in the context of this unifying view of SF1 and SF2 helicases....
Helicases of the superfamily (SF) 1 and 2 are involved in virtually all aspects of RNA and DNA metabolism. ...We discuss recen …
Eukaryotic DNA Replication Fork.
Burgers PMJ, Kunkel TA. Burgers PMJ, et al. Annu Rev Biochem. 2017 Jun 20;86:417-438. doi: 10.1146/annurev-biochem-061516-044709. Epub 2017 Mar 1. Annu Rev Biochem. 2017. PMID: 28301743 Free PMC article. Review.
This review focuses on the biogenesis and composition of the eukaryotic DNA replication fork, with an emphasis on the enzymes that synthesize DNA and repair discontinuities on the lagging strand of the replication fork. ...This review also discusses al …
This review focuses on the biogenesis and composition of the eukaryotic DNA replication fork, with an emphasis on the enzymes …
Cellular functions of eukaryotic RNA helicases and their links to human diseases.
Bohnsack KE, Yi S, Venus S, Jankowsky E, Bohnsack MT. Bohnsack KE, et al. Nat Rev Mol Cell Biol. 2023 Oct;24(10):749-769. doi: 10.1038/s41580-023-00628-5. Epub 2023 Jul 20. Nat Rev Mol Cell Biol. 2023. PMID: 37474727 Review.
RNA helicases are classified into the DEAD-box, DEAH/RHA, Ski2-like, Upf1-like and RIG-I families, and are the largest class of enzymes active in eukaryotic RNA metabolism - virtually all aspects of gene expression and its regulation involve RNA hel …
RNA helicases are classified into the DEAD-box, DEAH/RHA, Ski2-like, Upf1-like and RIG-I families, and are the l …
G-quadruplexes and helicases.
Mendoza O, Bourdoncle A, Boulé JB, Brosh RM Jr, Mergny JL. Mendoza O, et al. Nucleic Acids Res. 2016 Mar 18;44(5):1989-2006. doi: 10.1093/nar/gkw079. Epub 2016 Feb 15. Nucleic Acids Res. 2016. PMID: 26883636 Free PMC article. Review.
The first indication of how G-quadruplex structures could be unfolded enzymatically came in the late 1990s with reports that some well-known duplex DNA helicases resolved these structures in vitro. Since then, the number of studies reporting G-quadruplex DNA …
The first indication of how G-quadruplex structures could be unfolded enzymatically came in the late 1990s with reports that some well-known …
Mechanisms of hexameric helicases.
Fernandez AJ, Berger JM. Fernandez AJ, et al. Crit Rev Biochem Mol Biol. 2021 Dec;56(6):621-639. doi: 10.1080/10409238.2021.1954597. Epub 2021 Aug 17. Crit Rev Biochem Mol Biol. 2021. PMID: 34404299 Free PMC article. Review.
Ring-shaped hexameric helicases are essential motor proteins that separate duplex nucleic acid strands for DNA replication, recombination, and transcriptional regulation. ...How hexameric helicases productively engage client DNA or RNA segments and use …
Ring-shaped hexameric helicases are essential motor proteins that separate duplex nucleic acid strands for DNA replication, re …
G-quadruplex resolution: From molecular mechanisms to physiological relevance.
Sato K, Knipscheer P. Sato K, et al. DNA Repair (Amst). 2023 Oct;130:103552. doi: 10.1016/j.dnarep.2023.103552. Epub 2023 Aug 3. DNA Repair (Amst). 2023. PMID: 37572578 Free article. Review.
Specialised DNA helicases and single stranded DNA binding proteins that can resolve G4 structures play a crucial role in preventing genome instability. ...Recently, there has been considerable progress in our detailed understanding of how G4s are resolved, es …
Specialised DNA helicases and single stranded DNA binding proteins that can resolve G4 structures play a crucial role i …
The CMG DNA helicase and the core replisome.
Pellegrini L. Pellegrini L. Curr Opin Struct Biol. 2023 Aug;81:102612. doi: 10.1016/j.sbi.2023.102612. Epub 2023 May 25. Curr Opin Struct Biol. 2023. PMID: 37244171 Free article. Review.
Eukaryotic DNA replication is performed by the replisome, a large and dynamic multi-protein machine endowed with the required enzymatic components for the synthesis of new DNA. Recent cryo-electron microscopy (cryoEM) analyses have revealed the conserved architectur …
Eukaryotic DNA replication is performed by the replisome, a large and dynamic multi-protein machine endowed with the required enzymat …
Helicases: an overview.
Abdelhaleem M. Abdelhaleem M. Methods Mol Biol. 2010;587:1-12. doi: 10.1007/978-1-60327-355-8_1. Methods Mol Biol. 2010. PMID: 20225138 Review.
Helicases are essential enzymes involved in all aspects of nucleic acid metabolism including DNA replication, repair, recombination, transcription, ribosome biogenesis and RNA processing, translation, and decay. ...Because of their essential function, helicases …
Helicases are essential enzymes involved in all aspects of nucleic acid metabolism including DNA replication, repair, recombin …
The E1 proteins.
Bergvall M, Melendy T, Archambault J. Bergvall M, et al. Virology. 2013 Oct;445(1-2):35-56. doi: 10.1016/j.virol.2013.07.020. Epub 2013 Sep 10. Virology. 2013. PMID: 24029589 Free PMC article. Review.
E1, an ATP-dependent DNA helicase, is the only enzyme encoded by papillomaviruses (PVs). ...Here we review how different functional domains of E1 orchestrate viral DNA replication, with an emphasis on their interactions with substrate DNA, host …
E1, an ATP-dependent DNA helicase, is the only enzyme encoded by papillomaviruses (PVs). ...Here we review how differen …
DNA helicases and their roles in cancer.
Dhar S, Datta A, Brosh RM Jr. Dhar S, et al. DNA Repair (Amst). 2020 Dec;96:102994. doi: 10.1016/j.dnarep.2020.102994. Epub 2020 Oct 17. DNA Repair (Amst). 2020. PMID: 33137625 Review.
Flipping the coin, DNA helicases are frequently overexpressed in cancerous tissues and reduction in helicase gene expression results in reduced proliferation and growth capacity, as well as DNA damage induction and apoptosis of cancer cells. ...In this …
Flipping the coin, DNA helicases are frequently overexpressed in cancerous tissues and reduction in helicase gene expre …
4,092 results