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The following term was not found in PubMed: pichonianum
Page 1
Aspidosperma and Strychnos alkaloids: Chemistry and biology.
Zhao S, Sirasani G, Andrade RB. Zhao S, et al. Alkaloids Chem Biol. 2021;86:1-143. doi: 10.1016/bs.alkal.2021.05.001. Epub 2021 Sep 21. Alkaloids Chem Biol. 2021. PMID: 34565505 Review.
Of Nature's nearly 3000 unique monoterpene indole alkaloids derived from tryptophan, those members belonging to the Aspidosperma and Strychnos families continue to impact the fields of natural products (i.e., isolation, structure determination, biosynthesis) and organic ch …
Of Nature's nearly 3000 unique monoterpene indole alkaloids derived from tryptophan, those members belonging to the Aspidosperma and …
Aspidosperma species: A review of their chemistry and biological activities.
de Almeida VL, Silva CG, Silva AF, Campana PRV, Foubert K, Lopes JCD, Pieters L. de Almeida VL, et al. J Ethnopharmacol. 2019 Mar 1;231:125-140. doi: 10.1016/j.jep.2018.10.039. Epub 2018 Nov 3. J Ethnopharmacol. 2019. PMID: 30395977 Review.
The phytochemical aspects of the species of the genus Aspidosperma have been studied extensively. The monoterpene indole alkaloids are the main secondary metabolites in Aspidosperma species, and about 250 of them have been isolated showing a considerable structural …
The phytochemical aspects of the species of the genus Aspidosperma have been studied extensively. The monoterpene indole alkaloids ar …
Cytotoxic aspidosperma-type alkaloids from Melodinus suaveolens.
Fang ZY, He TT, Du SY, Zhang M, Zhang YQ, Fang L. Fang ZY, et al. Fitoterapia. 2020 Jun;143:104588. doi: 10.1016/j.fitote.2020.104588. Epub 2020 Apr 6. Fitoterapia. 2020. PMID: 32272162
Four new aspidosperma-type alkaloids, melosuavines J-M (1-4) were isolated from the leaves of Melodinus suaveolens. ...
Four new aspidosperma-type alkaloids, melosuavines J-M (1-4) were isolated from the leaves of Melodinus suaveolens. ...
Voatriafricanines A and B, Trimeric Vobasine-Aspidosperma-Aspidosperma Alkaloids from Voacanga africana.
Fouotsa H, Le Pogam P, Mkounga P, Lannang AM, Bernadat G, Vanheuverzwijn J, Zhou Z, Leblanc K, Rharrabti S, Nkengfack AE, Gallard JF, Fontaine V, Meyer F, Poupon E, Beniddir MA. Fouotsa H, et al. J Nat Prod. 2021 Oct 22;84(10):2755-2761. doi: 10.1021/acs.jnatprod.1c00812. Epub 2021 Sep 26. J Nat Prod. 2021. PMID: 34569237
Voatriafricanines A and B (1 and 2), the first examples of vobasine-aspidosperma-aspidosperma monoterpene trisindole alkaloids, were isolated from the stem barks of Voacanga africana, guided by a molecular networking strategy. ...
Voatriafricanines A and B (1 and 2), the first examples of vobasine-aspidosperma-aspidosperma monoterpene trisindole alkaloids …
Two new aspidosperma-type monoterpenoid indole alkaloids from Ervatamia officinalis.
Li BJ, Ma Y, Qian HS, He HP, Huang CH, Yu GD, Tang BQ. Li BJ, et al. J Asian Nat Prod Res. 2022 Jun 23:1-7. doi: 10.1080/10286020.2022.2090345. Online ahead of print. J Asian Nat Prod Res. 2022. PMID: 35735254
Two new aspidosperma-type monoterpenoid indole alkaloids, 16-O-methylvoafinine (1) and 14,15-diepi-voafinidine (2) were isolated from the aerial parts of Ervatamia officinalis. ...
Two new aspidosperma-type monoterpenoid indole alkaloids, 16-O-methylvoafinine (1) and 14,15-diepi-voafinidine (2) were isolated from …
Total Synthesis of Aspidosperma and Strychnos Alkaloids through Indole Dearomatization.
Saya JM, Ruijter E, Orru RVA. Saya JM, et al. Chemistry. 2019 Jul 5;25(38):8916-8935. doi: 10.1002/chem.201901130. Epub 2019 May 16. Chemistry. 2019. PMID: 30994212 Review.
Together with their structural complexity, this has attracted great interest from synthetic organic chemists. In this Review, the syntheses of Aspidosperma and Strychnos alkaloids through dearomatization of indoles are discussed....
Together with their structural complexity, this has attracted great interest from synthetic organic chemists. In this Review, the syntheses …
Tabernaesines A-I, Cytotoxic Aspidosperma-Aspidosperma-Type Bisindole Alkaloids from Tabernaemontana pachysiphon.
Yi WF, Ding X, Chen YZ, Adelakun TA, Zhang Y, Hao XJ. Yi WF, et al. J Nat Prod. 2020 Nov 25;83(11):3215-3222. doi: 10.1021/acs.jnatprod.9b00768. Epub 2020 Oct 28. J Nat Prod. 2020. PMID: 33112136
Twenty-one aspidosperma-aspidosperma alkaloids, including the new tabernaesines A-J (1-9), were obtained from Tabernaemontana pachysiphon. ...
Twenty-one aspidosperma-aspidosperma alkaloids, including the new tabernaesines A-J (1-9), were obtained from Tabernaemontana …
A natural small molecule aspidosperma-type alkaloid, hecubine, as a new TREM2 activator for alleviating lipopolysaccharide-induced neuroinflammation in vitro and in vivo.
Li L, He YL, Xu N, Wang XF, Song B, Tang BQ, Lee SM. Li L, et al. Redox Biol. 2024 Apr;70:103057. doi: 10.1016/j.redox.2024.103057. Epub 2024 Jan 24. Redox Biol. 2024. PMID: 38325196 Free PMC article.
Currently, there are no approved drugs specifically targeting TREM2 for CNS diseases. Aspidosperma alkaloids have shown potential as anti-inflammatory and neuroprotective agents. This study aimed to elucidate the potential therapeutic effect of Hecubine, a natural aspid …
Currently, there are no approved drugs specifically targeting TREM2 for CNS diseases. Aspidosperma alkaloids have shown potential as …
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft'.
Chen J, Yu Y, Wu J, Bao MF, Kongkiatpaiboon S, Schinnerl J, Cai XH. Chen J, et al. Bioorg Chem. 2021 Nov;116:105314. doi: 10.1016/j.bioorg.2021.105314. Epub 2021 Sep 1. Bioorg Chem. 2021. PMID: 34500306
Continued interest in bioactive monoterpenoid indole alkaloids and the purpose to explore the artificial cultivation influence on the chemical composition in the same plant species, 8 undescribed Aspidosperma-type alkaloids including two unprecedented trimers, taberdivarin …
Continued interest in bioactive monoterpenoid indole alkaloids and the purpose to explore the artificial cultivation influence on the chemic …
Cytotoxic aspidosperma-type alkaloids from Melodinus axillaris.
Fang L, He TT, Zhu KK, Zhang M, Zhou J, Zhang H. Fang L, et al. J Asian Nat Prod Res. 2019 Mar;21(3):284-290. doi: 10.1080/10286020.2018.1561668. Epub 2019 Jan 20. J Asian Nat Prod Res. 2019. PMID: 30661398
One new aspidosperma-type alkaloid, melotenine A (1), together with five known ones (2-6), was isolated from the leaves of Melodinus axillaris. Their structures were elucidated by detailed spectroscopic analysis and quantum chemical ECD calculation. The isolated aspidos …
One new aspidosperma-type alkaloid, melotenine A (1), together with five known ones (2-6), was isolated from the leaves of Melodinus …
353 results