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Page 1
Interferon therapy of hepatitis C: molecular insights into success and failure.
Swiss Med Wkly. 2010 Jan 9;140(1-2):3-11. doi: 10.4414/smw.2010.12670.
Swiss Med Wkly. 2010.
PMID: 19950038
Free article.
Review.
Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy.
Sarasin-Filipowicz M, Krol J, Markiewicz I, Heim MH, Filipowicz W.
Sarasin-Filipowicz M, et al.
Nat Med. 2009 Jan;15(1):31-3. doi: 10.1038/nm.1902. Epub 2009 Jan 4.
Nat Med. 2009.
PMID: 19122656
Clinical Trial.
Item in Clipboard
Interferon signaling and treatment outcome in chronic hepatitis C.
Sarasin-Filipowicz M, Oakeley EJ, Duong FH, Christen V, Terracciano L, Filipowicz W, Heim MH.
Sarasin-Filipowicz M, et al.
Proc Natl Acad Sci U S A. 2008 May 13;105(19):7034-9. doi: 10.1073/pnas.0707882105. Epub 2008 May 8.
Proc Natl Acad Sci U S A. 2008.
PMID: 18467494
Free PMC article.
Clinical Trial.
Item in Clipboard
Hepatitis C virus-linked mitochondrial dysfunction promotes hypoxia-inducible factor 1 alpha-mediated glycolytic adaptation.
Ripoli M, D'Aprile A, Quarato G, Sarasin-Filipowicz M, Gouttenoire J, Scrima R, Cela O, Boffoli D, Heim MH, Moradpour D, Capitanio N, Piccoli C.
Ripoli M, et al. Among authors: sarasin filipowicz m.
J Virol. 2010 Jan;84(1):647-60. doi: 10.1128/JVI.00769-09.
J Virol. 2010.
PMID: 19846525
Free PMC article.
Item in Clipboard
Alpha interferon induces long-lasting refractoriness of JAK-STAT signaling in the mouse liver through induction of USP18/UBP43.
Sarasin-Filipowicz M, Wang X, Yan M, Duong FH, Poli V, Hilton DJ, Zhang DE, Heim MH.
Sarasin-Filipowicz M, et al.
Mol Cell Biol. 2009 Sep;29(17):4841-51. doi: 10.1128/MCB.00224-09. Epub 2009 Jun 29.
Mol Cell Biol. 2009.
PMID: 19564419
Free PMC article.
Item in Clipboard
Cleavage of mitochondrial antiviral signaling protein in the liver of patients with chronic hepatitis C correlates with a reduced activation of the endogenous interferon system.
Bellecave P, Sarasin-Filipowicz M, Donzé O, Kennel A, Gouttenoire J, Meylan E, Terracciano L, Tschopp J, Sarrazin C, Berg T, Moradpour D, Heim MH.
Bellecave P, et al. Among authors: sarasin filipowicz m.
Hepatology. 2010 Apr;51(4):1127-36. doi: 10.1002/hep.23426.
Hepatology. 2010.
PMID: 20044805
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