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Items: 1 to 20 of 37

1.

Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1.

Bruijn LI, Houseweart MK, Kato S, Anderson KL, Anderson SD, Ohama E, Reaume AG, Scott RW, Cleveland DW.

Science. 1998 Sep 18;281(5384):1851-4.

2.

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.

Parkes TL, Elia AJ, Dickinson D, Hilliker AJ, Phillips JP, Boulianne GL.

Nat Genet. 1998 Jun;19(2):171-4.

PMID:
9620775
3.

Neuronal cell death.

Pettmann B, Henderson CE.

Neuron. 1998 Apr;20(4):633-47. Review. No abstract available.

4.

Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation.

Estévez AG, Spear N, Manuel SM, Radi R, Henderson CE, Barbeito L, Beckman JS.

J Neurosci. 1998 Feb 1;18(3):923-31.

5.

Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection.

Ghadge GD, Lee JP, Bindokas VP, Jordan J, Ma L, Miller RJ, Roos RP.

J Neurosci. 1997 Nov 15;17(22):8756-66.

6.

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis.

Kostic V, Jackson-Lewis V, de Bilbao F, Dubois-Dauphin M, Przedborski S.

Science. 1997 Jul 25;277(5325):559-62.

7.

Inhibition of ICE slows ALS in mice.

Friedlander RM, Brown RH, Gagliardini V, Wang J, Yuan J.

Nature. 1997 Jul 3;388(6637):31. No abstract available. Erratum in: Nature 1998 Apr 9;392(6676):560.

PMID:
9214497
8.

Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS.

Durham HD, Roy J, Dong L, Figlewicz DA.

J Neuropathol Exp Neurol. 1997 May;56(5):523-30.

9.

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

Bruijn LI, Becher MW, Lee MK, Anderson KL, Jenkins NA, Copeland NG, Sisodia SS, Rothstein JD, Borchelt DR, Price DL, Cleveland DW.

Neuron. 1997 Feb;18(2):327-38.

10.

Mutations in SOD1 associated with amyotrophic lateral sclerosis cause novel protein interactions.

Kunst CB, Mezey E, Brownstein MJ, Patterson D.

Nat Genet. 1997 Jan;15(1):91-4.

PMID:
8988176
11.

Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein.

Lyons TJ, Liu H, Goto JJ, Nersissian A, Roe JA, Graden JA, Café C, Ellerby LM, Bredesen DE, Gralla EB, Valentine JS.

Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12240-4.

12.

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury.

Reaume AG, Elliott JL, Hoffman EK, Kowall NW, Ferrante RJ, Siwek DF, Wilcox HM, Flood DG, Beal MF, Brown RH Jr, Scott RW, Snider WD.

Nat Genet. 1996 May;13(1):43-7.

PMID:
8673102
13.

Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32.

Slee EA, Zhu H, Chow SC, MacFarlane M, Nicholson DW, Cohen GM.

Biochem J. 1996 Apr 1;315 ( Pt 1):21-4.

14.

Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme.

Yamin TT, Ayala JM, Miller DK.

J Biol Chem. 1996 May 31;271(22):13273-82.

16.

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis.

Wiedau-Pazos M, Goto JJ, Rabizadeh S, Gralla EB, Roe JA, Lee MK, Valentine JS, Bredesen DE.

Science. 1996 Jan 26;271(5248):515-8.

PMID:
8560268
17.

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.

Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, Donaldson D, Goto J, O'Regan JP, Deng HX, et al.

Nature. 1993 Mar 4;362(6415):59-62. Erratum in: Nature. 1993 Jul 22;364(6435):362.

PMID:
8446170
18.

ALS, SOD and peroxynitrite.

Beckman JS, Carson M, Smith CD, Koppenol WH.

Nature. 1993 Aug 12;364(6438):584. No abstract available.

PMID:
8350919
19.
20.

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.

Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD, Caliendo J, Hentati A, Kwon YW, Deng HX, et al.

Science. 1994 Jun 17;264(5166):1772-5. Erratum in: Science 1995 Jul 14;269(5221):149.

PMID:
8209258
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