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Results: 1 to 20 of 50

1.

An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin.

Ibáñez CF, Ilag LL, Murray-Rust J, Persson H.

EMBO J. 1993 Jun;12(6):2281-93.

PMID:
8508763
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tissue-specific alternative splicing generates two isoforms of the trkA receptor.

Barker PA, Lomen-Hoerth C, Gensch EM, Meakin SO, Glass DJ, Shooter EM.

J Biol Chem. 1993 Jul 15;268(20):15150-7.

PMID:
8325889
[PubMed - indexed for MEDLINE]
Free Article
3.

Ectopic trkA expression mediates a NGF survival response in NGF-independent sensory neurons but not in parasympathetic neurons.

Allsopp TE, Robinson M, Wyatt S, Davies AM.

J Cell Biol. 1993 Dec;123(6 Pt 1):1555-66.

PMID:
8253850
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The carboxyl terminus of nerve growth factor is required for biological activity.

Drinkwater CC, Barker PA, Suter U, Shooter EM.

J Biol Chem. 1993 Nov 5;268(31):23202-7.

PMID:
8226840
[PubMed - indexed for MEDLINE]
Free Article
5.

Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites.

Holland DR, Cousens LS, Meng W, Matthews BW.

J Mol Biol. 1994 Jun 10;239(3):385-400.

PMID:
8201620
[PubMed - indexed for MEDLINE]
6.

Comparative equilibrium denaturation studies of the neurotrophins: nerve growth factor, brain-derived neurotrophic factor, neurotrophin 3, and neurotrophin 4/5.

Timm DE, de Haseth PL, Neet KE.

Biochemistry. 1994 Apr 19;33(15):4667-76.

PMID:
8161524
[PubMed - indexed for MEDLINE]
7.

Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses.

Stephens RM, Loeb DM, Copeland TD, Pawson T, Greene LA, Kaplan DR.

Neuron. 1994 Mar;12(3):691-705.

PMID:
8155326
[PubMed - indexed for MEDLINE]
8.

Production and characterization of recombinant mouse brain-derived neurotrophic factor and rat neurotrophin-3 expressed in insect cells.

Meyer SL, Lang DM, Forbes ME, Knight E Jr, Hirsch JD, Trusko SP, Scott RW.

J Neurochem. 1994 Mar;62(3):825-33.

PMID:
8113808
[PubMed - indexed for MEDLINE]
9.

Role of variable beta-hairpin loop in determining biological specificities in neurotrophin family.

Ilag LL, Lönnerberg P, Persson H, Ibáñez CF.

J Biol Chem. 1994 Aug 5;269(31):19941-6.

PMID:
8051078
[PubMed - indexed for MEDLINE]
Free Article
10.

Interactions of neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and the NT-3.BDNF heterodimer with the extracellular domains of the TrkB and TrkC receptors.

Philo J, Talvenheimo J, Wen J, Rosenfeld R, Welcher A, Arakawa T.

J Biol Chem. 1994 Nov 11;269(45):27840-6.

PMID:
7961713
[PubMed - indexed for MEDLINE]
Free Article
11.

Mutagenesis identifies amino-terminal residues of nerve growth factor necessary for Trk receptor binding and biological activity.

Shih A, Laramee GR, Schmelzer CH, Burton LE, Winslow JW.

J Biol Chem. 1994 Nov 4;269(44):27679-86.

PMID:
7961687
[PubMed - indexed for MEDLINE]
Free Article
12.

TrkA cross-linking mimics neuronal responses to nerve growth factor.

Clary DO, Weskamp G, Austin LR, Reichardt LF.

Mol Biol Cell. 1994 May;5(5):549-63.

PMID:
7919537
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Alteration of NH2-terminal residues of nerve growth factor affects activity and Trk binding without affecting stability or conformation.

Woo SB, Timm DE, Neet KE.

J Biol Chem. 1995 Mar 17;270(11):6278-85.

PMID:
7890765
[PubMed - indexed for MEDLINE]
Free Article
14.

The Trk family of neurotrophin receptors.

Barbacid M.

J Neurobiol. 1994 Nov;25(11):1386-403. Review.

PMID:
7852993
[PubMed - indexed for MEDLINE]
15.

Structure-function relationships in the neurotrophin family.

Ibáñez CF.

J Neurobiol. 1994 Nov;25(11):1349-61. Review.

PMID:
7852990
[PubMed - indexed for MEDLINE]
16.

Dimerization of cell surface receptors in signal transduction.

Heldin CH.

Cell. 1995 Jan 27;80(2):213-23. Review. No abstract available.

PMID:
7834741
[PubMed - indexed for MEDLINE]
Free Article
17.

Nerve growth factor: structure/function relationships.

Bradshaw RA, Murray-Rust J, Ibáñez CF, McDonald NQ, Lapatto R, Blundell TL.

Protein Sci. 1994 Nov;3(11):1901-13.

PMID:
7703837
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Chimeric tumor necrosis factor-TrkA receptors reveal that ligand-dependent activation of the TrkA tyrosine kinase is sufficient for differentiation and survival of PC12 cells.

Rovelli G, Heller RA, Canossa M, Shooter EM.

Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8717-21.

PMID:
7690970
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin.

Urfer R, Tsoulfas P, Soppet D, Escandón E, Parada LF, Presta LG.

EMBO J. 1994 Dec 15;13(24):5896-909.

PMID:
7529173
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Immunological determinants of nerve growth factor involved in p140trk (Trk) receptor binding.

Nanduri J, Vroegop SM, Buxser SE, Neet KE.

J Neurosci Res. 1994 Mar 1;37(4):433-44.

PMID:
7517456
[PubMed - indexed for MEDLINE]

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