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Results: 1 to 20 of 47

1.

Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila.

Slack C, Foley A, Partridge L.

PLoS One. 2012;7(10):e47699. doi: 10.1371/journal.pone.0047699. Epub 2012 Oct 16.

PMID:
23077661
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain.

Bai H, Kang P, Tatar M.

Aging Cell. 2012 Dec;11(6):978-85. doi: 10.1111/acel.12000. Epub 2012 Sep 18.

PMID:
22935001
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study.

Mattison JA, Roth GS, Beasley TM, Tilmont EM, Handy AM, Herbert RL, Longo DL, Allison DB, Young JE, Bryant M, Barnard D, Ward WF, Qi W, Ingram DK, de Cabo R.

Nature. 2012 Sep 13;489(7415):318-21. doi: 10.1038/nature11432.

PMID:
22932268
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Extension of Drosophila lifespan by Rosa damascena associated with an increased sensitivity to heat.

Schriner SE, Katoozi NS, Pham KQ, Gazarian M, Zarban A, Jafari M.

Biogerontology. 2012 Apr;13(2):105-17. doi: 10.1007/s10522-011-9357-0. Epub 2011 Sep 18.

PMID:
21928072
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The golden root, Rhodiola rosea, prolongs lifespan but decreases oxidative stress resistance in yeast Saccharomyces cerevisiae.

Bayliak MM, Lushchak VI.

Phytomedicine. 2011 Nov 15;18(14):1262-8. doi: 10.1016/j.phymed.2011.06.010. Epub 2011 Jul 30.

PMID:
21802922
[PubMed - indexed for MEDLINE]
6.

Glycolytic inhibition as a strategy for developing calorie restriction mimetics.

Ingram DK, Roth GS.

Exp Gerontol. 2011 Feb-Mar;46(2-3):148-54. doi: 10.1016/j.exger.2010.12.001. Epub 2010 Dec 15. Review.

PMID:
21167272
[PubMed - indexed for MEDLINE]
7.

Curcumin extends life span, improves health span, and modulates the expression of age-associated aging genes in Drosophila melanogaster.

Lee KS, Lee BS, Semnani S, Avanesian A, Um CY, Jeon HJ, Seong KM, Yu K, Min KJ, Jafari M.

Rejuvenation Res. 2010 Oct;13(5):561-70. doi: 10.1089/rej.2010.1031. Epub 2010 Jul 20.

PMID:
20645870
[PubMed - indexed for MEDLINE]
8.

With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging.

Kapahi P, Chen D, Rogers AN, Katewa SD, Li PW, Thomas EL, Kockel L.

Cell Metab. 2010 Jun 9;11(6):453-65. doi: 10.1016/j.cmet.2010.05.001. Review.

PMID:
20519118
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.

Panossian A, Wikman G, Sarris J.

Phytomedicine. 2010 Jun;17(7):481-93. doi: 10.1016/j.phymed.2010.02.002. Epub 2010 Apr 7. Review.

PMID:
20378318
[PubMed - indexed for MEDLINE]
10.

DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition.

Broughton SJ, Slack C, Alic N, Metaxakis A, Bass TM, Driege Y, Partridge L.

Aging Cell. 2010 Jun;9(3):336-46. doi: 10.1111/j.1474-9726.2010.00558.x. Epub 2010 Feb 12. Erratum in: Aging Cell. 2010 Oct;9(5):930.

PMID:
20156206
[PubMed - indexed for MEDLINE]
11.

Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1.

Onken B, Driscoll M.

PLoS One. 2010 Jan 18;5(1):e8758. doi: 10.1371/journal.pone.0008758.

PMID:
20090912
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea.

Schriner SE, Abrahamyan A, Avanessian A, Bussel I, Maler S, Gazarian M, Holmbeck MA, Jafari M.

Free Radic Res. 2009 Sep;43(9):836-43. doi: 10.1080/10715760903089724. Epub 2009 Jul 24.

PMID:
19634056
[PubMed - indexed for MEDLINE]
13.

Overexpression of Mn superoxide dismutase does not increase life span in mice.

Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, Richardson A.

J Gerontol A Biol Sci Med Sci. 2009 Nov;64(11):1114-25. doi: 10.1093/gerona/glp100. Epub 2009 Jul 24.

PMID:
19633237
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Caloric restriction delays disease onset and mortality in rhesus monkeys.

Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, Allison DB, Cruzen C, Simmons HA, Kemnitz JW, Weindruch R.

Science. 2009 Jul 10;325(5937):201-4. doi: 10.1126/science.1173635.

PMID:
19590001
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses.

Schriner SE, Avanesian A, Liu Y, Luesch H, Jafari M.

Free Radic Biol Med. 2009 Sep 1;47(5):577-84. doi: 10.1016/j.freeradbiomed.2009.05.025. Epub 2009 May 29.

PMID:
19486939
[PubMed - indexed for MEDLINE]
16.

Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan.

Humphrey DM, Toivonen JM, Giannakou M, Partridge L, Brand MD.

Exp Gerontol. 2009 May;44(5):316-27.

PMID:
19385039
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster.

Grandison RC, Wong R, Bass TM, Partridge L, Piper MD.

PLoS One. 2009;4(1):e4067. doi: 10.1371/journal.pone.0004067. Epub 2009 Jan 1.

PMID:
19119322
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The overexpression of major antioxidant enzymes does not extend the lifespan of mice.

Pérez VI, Van Remmen H, Bokov A, Epstein CJ, Vijg J, Richardson A.

Aging Cell. 2009 Feb;8(1):73-5. doi: 10.1111/j.1474-9726.2008.00449.x. Epub 2008 Dec 11.

PMID:
19077044
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Caloric restriction and aging: studies in mice and monkeys.

Anderson RM, Shanmuganayagam D, Weindruch R.

Toxicol Pathol. 2009 Jan;37(1):47-51. doi: 10.1177/0192623308329476. Epub 2008 Dec 15. Review.

PMID:
19075044
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Diet and aging.

Piper MD, Bartke A.

Cell Metab. 2008 Aug;8(2):99-104. doi: 10.1016/j.cmet.2008.06.012. Review.

PMID:
18680711
[PubMed - indexed for MEDLINE]
Free Article

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