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Results: 1 to 20 of 49

1.

Process for immune defect and chromosomal translocation during early thymocyte development lacking ATM.

Isoda T, Takagi M, Piao J, Nakagama S, Sato M, Masuda K, Ikawa T, Azuma M, Morio T, Kawamoto H, Mizutani S.

Blood. 2012 Jul 26;120(4):789-99. doi: 10.1182/blood-2012-02-413195. Epub 2012 Jun 18.

PMID:
22709691
[PubMed - indexed for MEDLINE]
Free Article
2.

53BP1-mediated DNA double strand break repair: insert bad pun here.

Noon AT, Goodarzi AA.

DNA Repair (Amst). 2011 Oct 10;10(10):1071-6. doi: 10.1016/j.dnarep.2011.07.012. Epub 2011 Aug 24. Review.

PMID:
21868291
[PubMed - indexed for MEDLINE]
3.

The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.

Hathcock KS, Farrington L, Ivanova I, Livak F, Selimyan R, Sen R, Williams J, Tai X, Hodes RJ.

PLoS One. 2011;6(6):e20639. doi: 10.1371/journal.pone.0020639. Epub 2011 Jun 3.

PMID:
21673984
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements.

Hakim O, Sung MH, Voss TC, Splinter E, John S, Sabo PJ, Thurman RE, Stamatoyannopoulos JA, de Laat W, Hager GL.

Genome Res. 2011 May;21(5):697-706. doi: 10.1101/gr.111153.110. Epub 2011 Apr 6.

PMID:
21471403
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Factors determining DNA double-strand break repair pathway choice in G2 phase.

Shibata A, Conrad S, Birraux J, Geuting V, Barton O, Ismail A, Kakarougkas A, Meek K, Taucher-Scholz G, Löbrich M, Jeggo PA.

EMBO J. 2011 Mar 16;30(6):1079-92. doi: 10.1038/emboj.2011.27. Epub 2011 Feb 11.

PMID:
21317870
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.

Lieber MR.

Annu Rev Biochem. 2010;79:181-211. doi: 10.1146/annurev.biochem.052308.093131. Review.

PMID:
20192759
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Antigen presentation in the thymus for positive selection and central tolerance induction.

Klein L, Hinterberger M, Wirnsberger G, Kyewski B.

Nat Rev Immunol. 2009 Dec;9(12):833-44. doi: 10.1038/nri2669. Review.

PMID:
19935803
[PubMed - indexed for MEDLINE]
8.

Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination.

Yin B, Savic V, Juntilla MM, Bredemeyer AL, Yang-Iott KS, Helmink BA, Koretzky GA, Sleckman BP, Bassing CH.

J Exp Med. 2009 Nov 23;206(12):2625-39. doi: 10.1084/jem.20091320. Epub 2009 Nov 2.

PMID:
19887394
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla.

McCaughtry TM, Baldwin TA, Wilken MS, Hogquist KA.

J Exp Med. 2008 Oct 27;205(11):2575-84. doi: 10.1084/jem.20080866. Epub 2008 Oct 20.

PMID:
18936237
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer.

Lavin MF.

Nat Rev Mol Cell Biol. 2008 Oct;9(10):759-69. doi: 10.1038/nrm2514. Review. Erratum in: Nat Rev Mol Cell Biol. 2008 Dec;9(12). doi: 10.1038/nrm2514.

PMID:
18813293
[PubMed - indexed for MEDLINE]
11.

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.

Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, Löbrich M, Jeggo PA.

Mol Cell. 2008 Jul 25;31(2):167-77. doi: 10.1016/j.molcel.2008.05.017.

PMID:
18657500
[PubMed - indexed for MEDLINE]
Free Article
12.

Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly.

Callén E, Nussenzweig MC, Nussenzweig A.

Oncogene. 2007 Dec 10;26(56):7759-64. Review.

PMID:
18066088
[PubMed - indexed for MEDLINE]
13.

Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes.

Huang CY, Sharma GG, Walker LM, Bassing CH, Pandita TK, Sleckman BP.

J Exp Med. 2007 Jun 11;204(6):1371-81. Epub 2007 May 14.

PMID:
17502661
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor alpha locus coding end breaks.

Vacchio MS, Olaru A, Livak F, Hodes RJ.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6323-8. Epub 2007 Apr 3.

PMID:
17405860
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes.

Skok JA, Gisler R, Novatchkova M, Farmer D, de Laat W, Busslinger M.

Nat Immunol. 2007 Apr;8(4):378-87. Epub 2007 Mar 4.

PMID:
17334367
[PubMed - indexed for MEDLINE]
16.

ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes.

Matei IR, Gladdy RA, Nutter LM, Canty A, Guidos CJ, Danska JS.

Blood. 2007 Mar 1;109(5):1887-96. Epub 2006 Oct 31.

PMID:
17077325
[PubMed - indexed for MEDLINE]
Free Article
17.

Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo.

Bertocci B, De Smet A, Weill JC, Reynaud CA.

Immunity. 2006 Jul;25(1):31-41.

PMID:
16860755
[PubMed - indexed for MEDLINE]
Free Article
18.

ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

Bredemeyer AL, Sharma GG, Huang CY, Helmink BA, Walker LM, Khor KC, Nuskey B, Sullivan KE, Pandita TK, Bassing CH, Sleckman BP.

Nature. 2006 Jul 27;442(7101):466-70. Epub 2006 Jun 14.

PMID:
16799570
[PubMed - indexed for MEDLINE]
19.

Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor.

Aifantis I, Mandal M, Sawai K, Ferrando A, Vilimas T.

Immunol Rev. 2006 Feb;209:159-69. Review.

PMID:
16448541
[PubMed - indexed for MEDLINE]
20.

ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection.

Matei IR, Guidos CJ, Danska JS.

Immunol Rev. 2006 Feb;209:142-58. Review.

PMID:
16448540
[PubMed - indexed for MEDLINE]

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