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Results: 1 to 20 of 34

1.

Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region.

Gao H, Wu X, Chai J, Han Z.

Cell Res. 2012 Dec;22(12):1716-20. doi: 10.1038/cr.2012.156. Epub 2012 Nov 13. No abstract available.

PMID:
23147789
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues.

Christian ML, Demorest ZL, Starker CG, Osborn MJ, Nyquist MD, Zhang Y, Carlson DF, Bradley P, Bogdanove AJ, Voytas DF.

PLoS One. 2012;7(9):e45383. doi: 10.1371/journal.pone.0045383. Epub 2012 Sep 24.

PMID:
23028976
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Chimeric TALE recombinases with programmable DNA sequence specificity.

Mercer AC, Gaj T, Fuller RP, Barbas CF 3rd.

Nucleic Acids Res. 2012 Nov;40(21):11163-72. doi: 10.1093/nar/gks875. Epub 2012 Sep 26.

PMID:
23019222
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Recognition of methylated DNA by TAL effectors.

Deng D, Yin P, Yan C, Pan X, Gong X, Qi S, Xie T, Mahfouz M, Zhu JK, Yan N, Shi Y.

Cell Res. 2012 Oct;22(10):1502-4. doi: 10.1038/cr.2012.127. Epub 2012 Sep 4. No abstract available.

PMID:
22945353
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains.

Cong L, Zhou R, Kuo YC, Cunniff M, Zhang F.

Nat Commun. 2012 Jul 24;3:968. doi: 10.1038/ncomms1962.

PMID:
22828628
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Advances in targeted genome editing.

Perez-Pinera P, Ousterout DG, Gersbach CA.

Curr Opin Chem Biol. 2012 Aug;16(3-4):268-77. doi: 10.1016/j.cbpa.2012.06.007. Epub 2012 Jul 20. Review.

PMID:
22819644
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

TAL effector RVD specificities and efficiencies.

Streubel J, Blücher C, Landgraf A, Boch J.

Nat Biotechnol. 2012 Jul 10;30(7):593-5. doi: 10.1038/nbt.2304. No abstract available.

PMID:
22781676
[PubMed - indexed for MEDLINE]
8.

Engineering synthetic TAL effectors with orthogonal target sites.

Garg A, Lohmueller JJ, Silver PA, Armel TZ.

Nucleic Acids Res. 2012 Aug;40(15):7584-95. doi: 10.1093/nar/gks404. Epub 2012 May 11.

PMID:
22581776
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

FLASH assembly of TALENs for high-throughput genome editing.

Reyon D, Tsai SQ, Khayter C, Foden JA, Sander JD, Joung JK.

Nat Biotechnol. 2012 May;30(5):460-5. doi: 10.1038/nbt.2170.

PMID:
22484455
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease.

Sun N, Liang J, Abil Z, Zhao H.

Mol Biosyst. 2012 Apr;8(4):1255-63. doi: 10.1039/c2mb05461b. Epub 2012 Feb 3.

PMID:
22301904
[PubMed - indexed for MEDLINE]
11.

Structural basis for sequence-specific recognition of DNA by TAL effectors.

Deng D, Yan C, Pan X, Mahfouz M, Wang J, Zhu JK, Shi Y, Yan N.

Science. 2012 Feb 10;335(6069):720-3. doi: 10.1126/science.1215670. Epub 2012 Jan 5.

PMID:
22223738
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The crystal structure of TAL effector PthXo1 bound to its DNA target.

Mak AN, Bradley P, Cernadas RA, Bogdanove AJ, Stoddard BL.

Science. 2012 Feb 10;335(6069):716-9. doi: 10.1126/science.1216211. Epub 2012 Jan 5.

PMID:
22223736
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection.

Pattanayak V, Ramirez CL, Joung JK, Liu DR.

Nat Methods. 2011 Aug 7;8(9):765-70. doi: 10.1038/nmeth.1670.

PMID:
21822273
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Heritable gene targeting in zebrafish using customized TALENs.

Huang P, Xiao A, Zhou M, Zhu Z, Lin S, Zhang B.

Nat Biotechnol. 2011 Aug 5;29(8):699-700. doi: 10.1038/nbt.1939. No abstract available.

PMID:
21822242
[PubMed - indexed for MEDLINE]
15.

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

Mussolino C, Morbitzer R, Lütge F, Dannemann N, Lahaye T, Cathomen T.

Nucleic Acids Res. 2011 Nov;39(21):9283-93. doi: 10.1093/nar/gkr597. Epub 2011 Aug 3.

PMID:
21813459
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting.

Cermak T, Doyle EL, Christian M, Wang L, Zhang Y, Schmidt C, Baller JA, Somia NV, Bogdanove AJ, Voytas DF.

Nucleic Acids Res. 2011 Jul;39(12):e82. doi: 10.1093/nar/gkr218. Epub 2011 Apr 14. Erratum in: Nucleic Acids Res. 2011 Sep 1;39(17):7879.

PMID:
21493687
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Assembly of custom TALE-type DNA binding domains by modular cloning.

Morbitzer R, Elsaesser J, Hausner J, Lahaye T.

Nucleic Acids Res. 2011 Jul;39(13):5790-9. doi: 10.1093/nar/gkr151. Epub 2011 Mar 18.

PMID:
21421566
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription.

Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P.

Nat Biotechnol. 2011 Feb;29(2):149-53. doi: 10.1038/nbt.1775. Epub 2011 Jan 19.

PMID:
21248753
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy.

Silva G, Poirot L, Galetto R, Smith J, Montoya G, Duchateau P, Pâques F.

Curr Gene Ther. 2011 Feb;11(1):11-27. Review.

PMID:
21182466
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A TALE nuclease architecture for efficient genome editing.

Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ.

Nat Biotechnol. 2011 Feb;29(2):143-8. doi: 10.1038/nbt.1755. Epub 2010 Dec 22.

PMID:
21179091
[PubMed - indexed for MEDLINE]
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