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Items: 15

1.

p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis.

Lee J, Sun C, Zhou Y, Lee J, Gokalp D, Herrema H, Park SW, Davis RJ, Ozcan U.

Nat Med. 2011 Sep 4;17(10):1251-60. doi: 10.1038/nm.2449.

2.

Novel genetic variations associated with salt sensitivity in the Korean population.

Rhee MY, Yang SJ, Oh SW, Park Y, Kim CI, Park HK, Park SW, Park CY.

Hypertens Res. 2011 May;34(5):606-11. doi: 10.1038/hr.2010.278. Epub 2011 Jan 13.

PMID:
21228780
3.

Serine/threonine kinase 39 is a candidate gene for primary hypertension especially in women: results from two cohort studies in Swedes.

Fava C, Danese E, Montagnana M, Sjögren M, Almgren P, Engström G, Nilsson P, Hedblad B, Guidi GC, Minuz P, Melander O.

J Hypertens. 2011 Mar;29(3):484-91. doi: 10.1097/HJH.0b013e328342b2c1.

PMID:
21178783
4.

Contribution of five top whole-genome association signals to hypertension in Han Chinese.

Niu WQ, Zhang Y, Ji KD, Gao PJ, Zhu DL.

J Hum Hypertens. 2011 Apr;25(4):278-80. doi: 10.1038/jhh.2010.114. Epub 2010 Dec 9. No abstract available.

PMID:
21150932
5.

STK39 is an independent risk factor for male hypertension in Han Chinese.

Chen LY, Zhao WH, Tian W, Guo J, Jiang F, Jin LJ, Sun YX, Chen KM, An LL, Li GD, Li Q, Li Y, Wu C, Zhao L, Wang WJ, Zheng GY, Li B, Li XQ, Hu J, Tian XL.

Int J Cardiol. 2012 Jan 26;154(2):122-7. doi: 10.1016/j.ijcard.2010.09.007. Epub 2010 Oct 2.

PMID:
20889219
6.

STK39 polymorphisms and blood pressure: an association study in British Caucasians and assessment of cis-acting influences on gene expression.

Cunnington MS, Kay C, Avery PJ, Mayosi BM, Koref MS, Keavney B.

BMC Med Genet. 2009 Dec 14;10:135. doi: 10.1186/1471-2350-10-135.

7.

Genome-wide association study identifies eight loci associated with blood pressure.

Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, van der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL; Wellcome Trust Case Control Consortium, Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, Bergman RN, Morken MA, Döring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS, Subirana I, Freimer NB, Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L, Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden JF, Seedorf U, Syvänen AC, Tognoni G, Lakatta EG, Sanna S, Scheet P, Schlessinger D, Scuteri A, Dörr M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T, Rettig R, Völker U, Galan P, Gut IG, Hercberg S, Lathrop GM, Zelenika D, Deloukas P, Soranzo N, Williams FM, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi NG, Völzke H, Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis G, Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J, Altshuler D, Strachan DP, Laan M, Meneton P, Wareham NJ, Uda M, Jarvelin MR, Mooser V, Melander O, Loos RJ, Elliott P, Abecasis GR, Caulfield M, Munroe PB.

Nat Genet. 2009 Jun;41(6):666-76. doi: 10.1038/ng.361. Epub 2009 May 10.

8.

Genome-wide association study of blood pressure and hypertension.

Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, Eiriksdottir G, Guo X, Arking DE, Mitchell GF, Mattace-Raso FU, Smith AV, Taylor K, Scharpf RB, Hwang SJ, Sijbrands EJ, Bis J, Harris TB, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JC, Boerwinkle E, Wang TJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, van Duijn CM.

Nat Genet. 2009 Jun;41(6):677-87. doi: 10.1038/ng.384. Epub 2009 May 10.

9.

From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene.

Wang Y, O'Connell JR, McArdle PF, Wade JB, Dorff SE, Shah SJ, Shi X, Pan L, Rampersaud E, Shen H, Kim JD, Subramanya AR, Steinle NI, Parsa A, Ober CC, Welling PA, Chakravarti A, Weder AB, Cooper RS, Mitchell BD, Shuldiner AR, Chang YP.

Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):226-31. doi: 10.1073/pnas.0808358106. Epub 2008 Dec 29.

10.

Sex differences in environmental and genetic factors for hypertension.

Ruixing Y, Jinzhen W, Shangling P, Weixiong L, Dezhai Y, Yuming C.

Am J Med. 2008 Sep;121(9):811-9. doi: 10.1016/j.amjmed.2008.04.026.

PMID:
18724972
11.
12.

Resistin-like molecule beta activates MAPKs, suppresses insulin signaling in hepatocytes, and induces diabetes, hyperlipidemia, and fatty liver in transgenic mice on a high fat diet.

Kushiyama A, Shojima N, Ogihara T, Inukai K, Sakoda H, Fujishiro M, Fukushima Y, Anai M, Ono H, Horike N, Viana AY, Uchijima Y, Nishiyama K, Shimosawa T, Fujita T, Katagiri H, Oka Y, Kurihara H, Asano T.

J Biol Chem. 2005 Dec 23;280(51):42016-25. Epub 2005 Oct 21.

13.
14.

Androgens induce expression of SPAK, a STE20/SPS1-related kinase, in LNCaP human prostate cancer cells.

Qi H, Labrie Y, Grenier J, Fournier A, Fillion C, Labrie C.

Mol Cell Endocrinol. 2001 Sep;182(2):181-92.

PMID:
11514053
15.

SPAK, a STE20/SPS1-related kinase that activates the p38 pathway.

Johnston AM, Naselli G, Gonez LJ, Martin RM, Harrison LC, DeAizpurua HJ.

Oncogene. 2000 Aug 31;19(37):4290-7.

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