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Results: 1 to 20 of 32

1.

Cis-acting polymorphisms affect complex traits through modifications of microRNA regulation pathways.

Arnold M, Ellwanger DC, Hartsperger ML, Pfeufer A, Stümpflen V.

PLoS One. 2012;7(5):e36694. doi: 10.1371/journal.pone.0036694. Epub 2012 May 11.

PMID:
22606281
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction.

Gurha P, Abreu-Goodger C, Wang T, Ramirez MO, Drumond AL, van Dongen S, Chen Y, Bartonicek N, Enright AJ, Lee B, Kelm RJ Jr, Reddy AK, Taffet GE, Bradley A, Wehrens XH, Entman ML, Rodriguez A.

Circulation. 2012 Jun 5;125(22):2751-61. doi: 10.1161/CIRCULATIONAHA.111.044354. Epub 2012 May 8.

PMID:
22570371
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart.

Jazbutyte V, Fiedler J, Kneitz S, Galuppo P, Just A, Holzmann A, Bauersachs J, Thum T.

Age (Dordr). 2013 Jun;35(3):747-62. doi: 10.1007/s11357-012-9407-9. Epub 2012 Apr 27.

PMID:
22538858
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

MicroRNAs in control of cardiac hypertrophy.

Da Costa Martins PA, De Windt LJ.

Cardiovasc Res. 2012 Mar 15;93(4):563-72. doi: 10.1093/cvr/cvs013. Epub 2012 Jan 19. Review.

PMID:
22266752
[PubMed - indexed for MEDLINE]
Free Article
5.

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy.

Shah S, Nelson CP, Gaunt TR, van der Harst P, Barnes T, Braund PS, Lawlor DA, Casas JP, Padmanabhan S, Drenos F, Kivimaki M, Talmud PJ, Humphries SE, Whittaker J, Morris RW, Whincup PH, Dominiczak A, Munroe PB, Johnson T, Goodall AH, Cambien F, Diemert P, Hengstenberg C, Ouwehand WH, Felix JF, Glazer NL, Tomaszewski M, Burton PR, Tobin MD, van Veldhuisen DJ, de Boer RA, Navis G, van Gilst WH, Mayosi BM, Thompson JR, Kumari M, MacFarlane PW, Day IN, Hingorani AD, Samani NJ.

Circ Cardiovasc Genet. 2011 Dec;4(6):626-35. doi: 10.1161/CIRCGENETICS.111.960203. Epub 2011 Sep 30.

PMID:
21965548
[PubMed - indexed for MEDLINE]
Free Article
6.

Common variants in RYR1 are associated with left ventricular hypertrophy assessed by electrocardiogram.

Hong KW, Shin DJ, Lee SH, Son NH, Go MJ, Lim JE, Shin C, Jang Y, Oh B.

Eur Heart J. 2012 May;33(10):1250-6. doi: 10.1093/eurheartj/ehr267. Epub 2011 Aug 9.

PMID:
21828061
[PubMed - indexed for MEDLINE]
Free Article
7.

A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes.

Jentzsch C, Leierseder S, Loyer X, Flohrschütz I, Sassi Y, Hartmann D, Thum T, Laggerbauer B, Engelhardt S.

J Mol Cell Cardiol. 2012 Jan;52(1):13-20. doi: 10.1016/j.yjmcc.2011.07.010. Epub 2011 Jul 23.

PMID:
21801730
[PubMed - indexed for MEDLINE]
8.

Attenuation of microRNA-22 derepressed PTEN to effectively protect rat cardiomyocytes from hypertrophy.

Xu XD, Song XW, Li Q, Wang GK, Jing Q, Qin YW.

J Cell Physiol. 2012 Apr;227(4):1391-8. doi: 10.1002/jcp.22852.

PMID:
21618527
[PubMed - indexed for MEDLINE]
9.

Common variation at the 11-β hydroxysteroid dehydrogenase type 1 gene is associated with left ventricular mass.

Rahman TJ, Mayosi BM, Hall D, Avery PJ, Stewart PM, Connell JM, Watkins H, Keavney B.

Circ Cardiovasc Genet. 2011 Apr;4(2):156-62. doi: 10.1161/CIRCGENETICS.110.958496. Epub 2011 Mar 14.

PMID:
21402901
[PubMed - indexed for MEDLINE]
Free Article
10.

Increased CD36 expression in middle-aged mice contributes to obesity-related cardiac hypertrophy in the absence of cardiac dysfunction.

Sung MM, Koonen DP, Soltys CL, Jacobs RL, Febbraio M, Dyck JR.

J Mol Med (Berl). 2011 May;89(5):459-69. doi: 10.1007/s00109-010-0720-4. Epub 2011 Mar 10.

PMID:
21387178
[PubMed - indexed for MEDLINE]
11.

Common variation in the CD36 (fatty acid translocase) gene is associated with left-ventricular mass.

Hall D, Mayosi BM, Rahman TJ, Avery PJ, Watkins HC, Keavney B.

J Hypertens. 2011 Apr;29(4):690-5. doi: 10.1097/HJH.0b013e3283440115.

PMID:
21346626
[PubMed - indexed for MEDLINE]
12.

Genetic variation in microRNA networks: the implications for cancer research.

Ryan BM, Robles AI, Harris CC.

Nat Rev Cancer. 2010 Jun;10(6):389-402. doi: 10.1038/nrc2867. Review. Erratum in: Nat Rev Cancer. 2010 Jul;10(7):523.

PMID:
20495573
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

STK39 polymorphisms and blood pressure: an association study in British Caucasians and assessment of cis-acting influences on gene expression.

Cunnington MS, Kay C, Avery PJ, Mayosi BM, Koref MS, Keavney B.

BMC Med Genet. 2009 Dec 14;10:135. doi: 10.1186/1471-2350-10-135.

PMID:
20003416
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.

Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, Lumley T, Aulchenko YS, König IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, Erdmann J, Schnabel RB, Dörr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Völker U, Ingelsson E, Kullo I, Haerting J, O'Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, van Duijn CM, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Völzke H, Blankenberg S.

JAMA. 2009 Jul 8;302(2):168-78. doi: 10.1001/jama.2009.978-a.

PMID:
19584346
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss.

Mencía A, Modamio-Høybjør S, Redshaw N, Morín M, Mayo-Merino F, Olavarrieta L, Aguirre LA, del Castillo I, Steel KP, Dalmay T, Moreno F, Moreno-Pelayo MA.

Nat Genet. 2009 May;41(5):609-13. doi: 10.1038/ng.355. Epub 2009 Apr 12.

PMID:
19363479
[PubMed - indexed for MEDLINE]
16.

Ambulatory blood pressure is associated with polymorphic variation in P2X receptor genes.

Palomino-Doza J, Rahman TJ, Avery PJ, Mayosi BM, Farrall M, Watkins H, Edwards CR, Keavney B.

Hypertension. 2008 Nov;52(5):980-5. doi: 10.1161/HYPERTENSIONAHA.108.113282. Epub 2008 Oct 13.

PMID:
18852390
[PubMed - indexed for MEDLINE]
Free Article
17.

The two Cs: ceramide and cardiomyopathy.

Getz GS.

J Lipid Res. 2008 Oct;49(10):2077-8. doi: 10.1194/jlr.E800015-JLR200. Epub 2008 Jul 23. No abstract available.

PMID:
18650556
[PubMed - indexed for MEDLINE]
Free Article
18.

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy.

Park TS, Hu Y, Noh HL, Drosatos K, Okajima K, Buchanan J, Tuinei J, Homma S, Jiang XC, Abel ED, Goldberg IJ.

J Lipid Res. 2008 Oct;49(10):2101-12. doi: 10.1194/jlr.M800147-JLR200. Epub 2008 May 30.

PMID:
18515784
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass.

Petretto E, Sarwar R, Grieve I, Lu H, Kumaran MK, Muckett PJ, Mangion J, Schroen B, Benson M, Punjabi PP, Prasad SK, Pennell DJ, Kiesewetter C, Tasheva ES, Corpuz LM, Webb MD, Conrad GW, Kurtz TW, Kren V, Fischer J, Hubner N, Pinto YM, Pravenec M, Aitman TJ, Cook SA.

Nat Genet. 2008 May;40(5):546-52. doi: 10.1038/ng.134.

PMID:
18443592
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Genome-wide linkage analysis of electrocardiographic and echocardiographic left ventricular hypertrophy in families with hypertension.

Mayosi BM, Avery PJ, Farrall M, Keavney B, Watkins H.

Eur Heart J. 2008 Feb;29(4):525-30. doi: 10.1093/eurheartj/ehn028.

PMID:
18276622
[PubMed - indexed for MEDLINE]
Free Article

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