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Results: 1 to 20 of 47

1.

Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer.

Shain AH, Giacomini CP, Matsukuma K, Karikari CA, Bashyam MD, Hidalgo M, Maitra A, Pollack JR.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):E252-9. doi: 10.1073/pnas.1114817109. Epub 2012 Jan 10.

PMID:
22233809
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells.

Ram O, Goren A, Amit I, Shoresh N, Yosef N, Ernst J, Kellis M, Gymrek M, Issner R, Coyne M, Durham T, Zhang X, Donaghey J, Epstein CB, Regev A, Bernstein BE.

Cell. 2011 Dec 23;147(7):1628-39. doi: 10.1016/j.cell.2011.09.057.

PMID:
22196736
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner.

Wang T, Chen K, Zeng X, Yang J, Wu Y, Shi X, Qin B, Zeng L, Esteban MA, Pan G, Pei D.

Cell Stem Cell. 2011 Dec 2;9(6):575-87. doi: 10.1016/j.stem.2011.10.005. Epub 2011 Nov 17.

PMID:
22100412
[PubMed - indexed for MEDLINE]
Free Article
4.

Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.

DiTacchio L, Le HD, Vollmers C, Hatori M, Witcher M, Secombe J, Panda S.

Science. 2011 Sep 30;333(6051):1881-5. doi: 10.1126/science.1206022.

PMID:
21960634
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.

Lin W, Cao J, Liu J, Beshiri ML, Fujiwara Y, Francis J, Cherniack AD, Geisen C, Blair LP, Zou MR, Shen X, Kawamori D, Liu Z, Grisanzio C, Watanabe H, Minamishima YA, Zhang Q, Kulkarni RN, Signoretti S, Rodig SJ, Bronson RT, Orkin SH, Tuck DP, Benevolenskaya EV, Meyerson M, Kaelin WG Jr, Yan Q.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13379-86. doi: 10.1073/pnas.1110104108. Epub 2011 Jul 25.

PMID:
21788502
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway.

Kottakis F, Polytarchou C, Foltopoulou P, Sanidas I, Kampranis SC, Tsichlis PN.

Mol Cell. 2011 Jul 22;43(2):285-98. doi: 10.1016/j.molcel.2011.06.020.

PMID:
21777817
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells.

Tzatsos A, Paskaleva P, Lymperi S, Contino G, Stoykova S, Chen Z, Wong KK, Bardeesy N.

J Biol Chem. 2011 Sep 23;286(38):33061-9. doi: 10.1074/jbc.M111.257667. Epub 2011 Jul 11.

PMID:
21757686
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.

Corcoran RB, Contino G, Deshpande V, Tzatsos A, Conrad C, Benes CH, Levy DE, Settleman J, Engelman JA, Bardeesy N.

Cancer Res. 2011 Jul 15;71(14):5020-9. doi: 10.1158/0008-5472.CAN-11-0908. Epub 2011 May 17.

PMID:
21586612
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Histone methylation by PRC2 is inhibited by active chromatin marks.

Schmitges FW, Prusty AB, Faty M, Stützer A, Lingaraju GM, Aiwazian J, Sack R, Hess D, Li L, Zhou S, Bunker RD, Wirth U, Bouwmeester T, Bauer A, Ly-Hartig N, Zhao K, Chan H, Gu J, Gut H, Fischle W, Müller J, Thomä NH.

Mol Cell. 2011 May 6;42(3):330-41. doi: 10.1016/j.molcel.2011.03.025.

PMID:
21549310
[PubMed - indexed for MEDLINE]
Free Article
10.

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy.

Collisson EA, Sadanandam A, Olson P, Gibb WJ, Truitt M, Gu S, Cooc J, Weinkle J, Kim GE, Jakkula L, Feiler HS, Ko AH, Olshen AB, Danenberg KL, Tempero MA, Spellman PT, Hanahan D, Gray JW.

Nat Med. 2011 Apr;17(4):500-3. doi: 10.1038/nm.2344. Epub 2011 Apr 3.

PMID:
21460848
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genome profiling of pancreatic adenocarcinoma.

Birnbaum DJ, Adélaïde J, Mamessier E, Finetti P, Lagarde A, Monges G, Viret F, Gonçalvès A, Turrini O, Delpero JR, Iovanna J, Giovannini M, Birnbaum D, Chaffanet M.

Genes Chromosomes Cancer. 2011 Jun;50(6):456-65. doi: 10.1002/gcc.20870. Epub 2011 Mar 15.

PMID:
21412932
[PubMed - indexed for MEDLINE]
12.

Cancer epigenetics reaches mainstream oncology.

Rodríguez-Paredes M, Esteller M.

Nat Med. 2011 Mar;17(3):330-9. doi: 10.1038/nm.2305. Review.

PMID:
21386836
[PubMed - indexed for MEDLINE]
13.

KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia.

He J, Nguyen AT, Zhang Y.

Blood. 2011 Apr 7;117(14):3869-80. doi: 10.1182/blood-2010-10-312736. Epub 2011 Feb 10.

PMID:
21310926
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

H3K36 methylation antagonizes PRC2-mediated H3K27 methylation.

Yuan W, Xu M, Huang C, Liu N, Chen S, Zhu B.

J Biol Chem. 2011 Mar 11;286(10):7983-9. doi: 10.1074/jbc.M110.194027. Epub 2011 Jan 14.

PMID:
21239496
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Cooperative epigenetic modulation by cancer amplicon genes.

Rui L, Emre NC, Kruhlak MJ, Chung HJ, Steidl C, Slack G, Wright GW, Lenz G, Ngo VN, Shaffer AL, Xu W, Zhao H, Yang Y, Lamy L, Davis RE, Xiao W, Powell J, Maloney D, Thomas CJ, Möller P, Rosenwald A, Ott G, Muller-Hermelink HK, Savage K, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Weisenburger DD, Chan WC, Gascoyne RD, Levens D, Staudt LM.

Cancer Cell. 2010 Dec 14;18(6):590-605. doi: 10.1016/j.ccr.2010.11.013.

PMID:
21156283
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Essential functions of the histone demethylase lid.

Li L, Greer C, Eisenman RN, Secombe J.

PLoS Genet. 2010 Nov 24;6(11):e1001221. doi: 10.1371/journal.pgen.1001221.

PMID:
21124823
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation.

Wilson BG, Wang X, Shen X, McKenna ES, Lemieux ME, Cho YJ, Koellhoffer EC, Pomeroy SL, Orkin SH, Roberts CW.

Cancer Cell. 2010 Oct 19;18(4):316-28. doi: 10.1016/j.ccr.2010.09.006. Erratum in: Cancer Cell. 2011 Jan 18;19(1):153.

PMID:
20951942
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.

Kim J, Woo AJ, Chu J, Snow JW, Fujiwara Y, Kim CG, Cantor AB, Orkin SH.

Cell. 2010 Oct 15;143(2):313-24. doi: 10.1016/j.cell.2010.09.010.

PMID:
20946988
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers.

Chi P, Allis CD, Wang GG.

Nat Rev Cancer. 2010 Jul;10(7):457-69. doi: 10.1038/nrc2876. Review.

PMID:
20574448
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Implications of enhancer of zeste homologue 2 expression in pancreatic ductal adenocarcinoma.

Toll AD, Dasgupta A, Potoczek M, Yeo CJ, Kleer CG, Brody JR, Witkiewicz AK.

Hum Pathol. 2010 Sep;41(9):1205-9. doi: 10.1016/j.humpath.2010.03.004. Epub 2010 Jun 22.

PMID:
20573371
[PubMed - indexed for MEDLINE]

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