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Results: 1 to 20 of 73

1.

TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection.

Chen H, Ndhlovu ZM, Liu D, Porter LC, Fang JW, Darko S, Brockman MA, Miura T, Brumme ZL, Schneidewind A, Piechocka-Trocha A, Cesa KT, Sela J, Cung TD, Toth I, Pereyra F, Yu XG, Douek DC, Kaufmann DE, Allen TM, Walker BD.

Nat Immunol. 2012 Jun 10;13(7):691-700. doi: 10.1038/ni.2342.

PMID:
22683743
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

HLA B*5701-positive long-term nonprogressors/elite controllers are not distinguished from progressors by the clonal composition of HIV-specific CD8+ T cells.

Mendoza D, Royce C, Ruff LE, Ambrozak DR, Quigley MF, Dang T, Venturi V, Price DA, Douek DC, Migueles SA, Connors M.

J Virol. 2012 Apr;86(7):4014-8. doi: 10.1128/JVI.06982-11. Epub 2012 Jan 25.

PMID:
22278241
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Why don't CD8+ T cells reduce the lifespan of SIV-infected cells in vivo?

Elemans M, Seich Al Basatena NK, Klatt NR, Gkekas C, Silvestri G, Asquith B.

PLoS Comput Biol. 2011 Sep;7(9):e1002200. doi: 10.1371/journal.pcbi.1002200. Epub 2011 Sep 29.

PMID:
21990968
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection.

Ganusov VV, Goonetilleke N, Liu MK, Ferrari G, Shaw GM, McMichael AJ, Borrow P, Korber BT, Perelson AS.

J Virol. 2011 Oct;85(20):10518-28. doi: 10.1128/JVI.00655-11. Epub 2011 Aug 10.

PMID:
21835793
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Escape from highly effective public CD8+ T-cell clonotypes by HIV.

Iglesias MC, Almeida JR, Fastenackels S, van Bockel DJ, Hashimoto M, Venturi V, Gostick E, Urrutia A, Wooldridge L, Clement M, Gras S, Wilmann PG, Autran B, Moris A, Rossjohn J, Davenport MP, Takiguchi M, Brander C, Douek DC, Kelleher AD, Price DA, Appay V.

Blood. 2011 Aug 25;118(8):2138-49. doi: 10.1182/blood-2011-01-328781. Epub 2011 Jul 6.

PMID:
21734237
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.

Ferrari G, Korber B, Goonetilleke N, Liu MK, Turnbull EL, Salazar-Gonzalez JF, Hawkins N, Self S, Watson S, Betts MR, Gay C, McGhee K, Pellegrino P, Williams I, Tomaras GD, Haynes BF, Gray CM, Borrow P, Roederer M, McMichael AJ, Weinhold KJ.

PLoS Pathog. 2011 Feb 10;7(2):e1001273. doi: 10.1371/journal.ppat.1001273.

PMID:
21347345
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G Jr, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC Jr, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL Jr, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC 3rd, Olender SA, Ostrowski M, Owen WF Jr, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC 3rd, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM Jr, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, Theisen W, Torres R, Tosiello L, Tremblay C, Tribble MA, Trinh PD, Tsao A, Ueda P, Vaccaro A, Valadas E, Vanig TJ, Vecino I, Vega VM, Veikley W, Wade BH, Walworth C, Wanidworanun C, Ward DJ, Warner DA, Weber RD, Webster D, Weis S, Wheeler DA, White DJ, Wilkins E, Winston A, Wlodaver CG, van't Wout A, Wright DP, Yang OO, Yurdin DL, Zabukovic BW, Zachary KC, Zeeman B, Zhao M.

Science. 2010 Dec 10;330(6010):1551-7. doi: 10.1126/science.1195271. Epub 2010 Nov 4.

PMID:
21051598
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Phylogenetic approach reveals that virus genotype largely determines HIV set-point viral load.

Alizon S, von Wyl V, Stadler T, Kouyos RD, Yerly S, Hirschel B, Böni J, Shah C, Klimkait T, Furrer H, Rauch A, Vernazza PL, Bernasconi E, Battegay M, Bürgisser P, Telenti A, Günthard HF, Bonhoeffer S; Swiss HIV Cohort Study.

PLoS Pathog. 2010 Sep 30;6(9):e1001123. doi: 10.1371/journal.ppat.1001123.

PMID:
20941398
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Fluidity of HIV-1-specific T-cell responses during acute and early subtype C HIV-1 infection and associations with early disease progression.

Mlotshwa M, Riou C, Chopera D, de Assis Rosa D, Ntale R, Treunicht F, Woodman Z, Werner L, van Loggerenberg F, Mlisana K, Abdool Karim S, Williamson C, Gray CM; CAPRISA 002 Study Team.

J Virol. 2010 Nov;84(22):12018-29. doi: 10.1128/JVI.01472-10. Epub 2010 Sep 8.

PMID:
20826686
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing.

Fischer W, Ganusov VV, Giorgi EE, Hraber PT, Keele BF, Leitner T, Han CS, Gleasner CD, Green L, Lo CC, Nag A, Wallstrom TC, Wang S, McMichael AJ, Haynes BF, Hahn BH, Perelson AS, Borrow P, Shaw GM, Bhattacharya T, Korber BT.

PLoS One. 2010 Aug 20;5(8):e12303. doi: 10.1371/journal.pone.0012303.

PMID:
20808830
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Additive contribution of HLA class I alleles in the immune control of HIV-1 infection.

Leslie A, Matthews PC, Listgarten J, Carlson JM, Kadie C, Ndung'u T, Brander C, Coovadia H, Walker BD, Heckerman D, Goulder PJ.

J Virol. 2010 Oct;84(19):9879-88. doi: 10.1128/JVI.00320-10. Epub 2010 Jul 21.

PMID:
20660184
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Impaired replication capacity of acute/early viruses in persons who become HIV controllers.

Miura T, Brumme ZL, Brockman MA, Rosato P, Sela J, Brumme CJ, Pereyra F, Kaufmann DE, Trocha A, Block BL, Daar ES, Connick E, Jessen H, Kelleher AD, Rosenberg E, Markowitz M, Schafer K, Vaida F, Iwamoto A, Little S, Walker BD.

J Virol. 2010 Aug;84(15):7581-91. doi: 10.1128/JVI.00286-10. Epub 2010 May 26.

PMID:
20504921
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells.

Makedonas G, Hutnick N, Haney D, Amick AC, Gardner J, Cosma G, Hersperger AR, Dolfi D, Wherry EJ, Ferrari G, Betts MR.

PLoS Pathog. 2010 Mar 5;6(3):e1000798. doi: 10.1371/journal.ppat.1000798.

PMID:
20221423
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

HIV RNA level in early infection is predicted by viral load in the transmission source.

Hecht FM, Hartogensis W, Bragg L, Bacchetti P, Atchison R, Grant R, Barbour J, Deeks SG.

AIDS. 2010 Apr 24;24(7):941-5. doi: 10.1097/QAD.0b013e328337b12e.

PMID:
20168202
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype.

Dinges WL, Richardt J, Friedrich D, Jalbert E, Liu Y, Stevens CE, Maenza J, Collier AC, Geraghty DE, Smith J, Moodie Z, Mullins JI, McElrath MJ, Horton H.

J Virol. 2010 May;84(9):4461-8. doi: 10.1128/JVI.02438-09. Epub 2010 Feb 10.

PMID:
20147397
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The immune response during acute HIV-1 infection: clues for vaccine development.

McMichael AJ, Borrow P, Tomaras GD, Goonetilleke N, Haynes BF.

Nat Rev Immunol. 2010 Jan;10(1):11-23. doi: 10.1038/nri2674. Epub 2009 Dec 11. Review.

PMID:
20010788
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection.

Petrovas C, Chaon B, Ambrozak DR, Price DA, Melenhorst JJ, Hill BJ, Geldmacher C, Casazza JP, Chattopadhyay PK, Roederer M, Douek DC, Mueller YM, Jacobson JM, Kulkarni V, Felber BK, Pavlakis GN, Katsikis PD, Koup RA.

J Immunol. 2009 Jul 15;183(2):1120-32. doi: 10.4049/jimmunol.0900182. Epub 2009 Jun 29.

PMID:
19564339
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection.

Salazar-Gonzalez JF, Salazar MG, Keele BF, Learn GH, Giorgi EE, Li H, Decker JM, Wang S, Baalwa J, Kraus MH, Parrish NF, Shaw KS, Guffey MB, Bar KJ, Davis KL, Ochsenbauer-Jambor C, Kappes JC, Saag MS, Cohen MS, Mulenga J, Derdeyn CA, Allen S, Hunter E, Markowitz M, Hraber P, Perelson AS, Bhattacharya T, Haynes BF, Korber BT, Hahn BH, Shaw GM.

J Exp Med. 2009 Jun 8;206(6):1273-89. doi: 10.1084/jem.20090378. Epub 2009 Jun 1.

PMID:
19487424
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection.

Goonetilleke N, Liu MK, Salazar-Gonzalez JF, Ferrari G, Giorgi E, Ganusov VV, Keele BF, Learn GH, Turnbull EL, Salazar MG, Weinhold KJ, Moore S; CHAVI Clinical Core B, Letvin N, Haynes BF, Cohen MS, Hraber P, Bhattacharya T, Borrow P, Perelson AS, Hahn BH, Shaw GM, Korber BT, McMichael AJ.

J Exp Med. 2009 Jun 8;206(6):1253-72. doi: 10.1084/jem.20090365. Epub 2009 Jun 1.

PMID:
19487423
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells.

Streeck H, Jolin JS, Qi Y, Yassine-Diab B, Johnson RC, Kwon DS, Addo MM, Brumme C, Routy JP, Little S, Jessen HK, Kelleher AD, Hecht FM, Sekaly RP, Rosenberg ES, Walker BD, Carrington M, Altfeld M.

J Virol. 2009 Aug;83(15):7641-8. doi: 10.1128/JVI.00182-09. Epub 2009 May 20.

PMID:
19458000
[PubMed - indexed for MEDLINE]
Free PMC Article

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