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Items: 1 to 20 of 54

1.

The 3A protein from multiple picornaviruses utilizes the golgi adaptor protein ACBD3 to recruit PI4KIIIβ.

Greninger AL, Knudsen GM, Betegon M, Burlingame AL, Derisi JL.

J Virol. 2012 Apr;86(7):3605-16. doi: 10.1128/JVI.06778-11. Epub 2012 Jan 18.

2.

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites.

Sasaki J, Ishikawa K, Arita M, Taniguchi K.

EMBO J. 2012 Feb 1;31(3):754-66. doi: 10.1038/emboj.2011.429. Epub 2011 Nov 29.

3.

A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans.

Walker AK, Jacobs RL, Watts JL, Rottiers V, Jiang K, Finnegan DM, Shioda T, Hansen M, Yang F, Niebergall LJ, Vance DE, Tzoneva M, Hart AC, Näär AM.

Cell. 2011 Nov 11;147(4):840-52. doi: 10.1016/j.cell.2011.09.045. Epub 2011 Oct 27.

4.

Cholesterol metabolism in Huntington disease.

Karasinska JM, Hayden MR.

Nat Rev Neurol. 2011 Sep 6;7(10):561-72. doi: 10.1038/nrneurol.2011.132. Review.

PMID:
21894212
5.

Tissue- and paralogue-specific functions of acyl-CoA-binding proteins in lipid metabolism in Caenorhabditis elegans.

Elle IC, Simonsen KT, Olsen LC, Birck PK, Ehmsen S, Tuck S, Le TT, Færgeman NJ.

Biochem J. 2011 Jul 15;437(2):231-41. doi: 10.1042/BJ20102099.

PMID:
21539519
6.

Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques.

Tang JJ, Li JG, Qi W, Qiu WW, Li PS, Li BL, Song BL.

Cell Metab. 2011 Jan 5;13(1):44-56. doi: 10.1016/j.cmet.2010.12.004.

7.

Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c.

Ferré P, Foufelle F.

Diabetes Obes Metab. 2010 Oct;12 Suppl 2:83-92. doi: 10.1111/j.1463-1326.2010.01275.x. Review.

PMID:
21029304
8.

SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism.

Ponugoti B, Kim DH, Xiao Z, Smith Z, Miao J, Zang M, Wu SY, Chiang CM, Veenstra TD, Kemper JK.

J Biol Chem. 2010 Oct 29;285(44):33959-70. doi: 10.1074/jbc.M110.122978. Epub 2010 Sep 3.

9.

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Näär AM.

Genes Dev. 2010 Jul 1;24(13):1403-17. doi: 10.1101/gad.1901210.

10.

Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice.

Landrock D, Atshaves BP, McIntosh AL, Landrock KK, Schroeder F, Kier AB.

Lipids. 2010 Jul;45(7):567-80. doi: 10.1007/s11745-010-3437-9. Epub 2010 Jun 18.

11.

ACBP knockdown leads to down-regulation of genes encoding rate-limiting enzymes in cholesterol and fatty acid metabolism.

Vock C, Biedasek K, Boomgaarden I, Heins A, Nitz I, Döring F.

Cell Physiol Biochem. 2010;25(6):675-86. doi: 10.1159/000315087. Epub 2010 May 18.

PMID:
20511713
12.

The Akt-SREBP nexus: cell signaling meets lipid metabolism.

Krycer JR, Sharpe LJ, Luu W, Brown AJ.

Trends Endocrinol Metab. 2010 May;21(5):268-76. doi: 10.1016/j.tem.2010.01.001. Epub 2010 Feb 1. Review.

PMID:
20117946
13.

Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): an emerging signaling molecule.

Fan J, Liu J, Culty M, Papadopoulos V.

Prog Lipid Res. 2010 Jul;49(3):218-34. doi: 10.1016/j.plipres.2009.12.003. Epub 2010 Jan 4. Review.

14.

Role of NMDA receptor-dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries.

Taghibiglou C, Martin HG, Lai TW, Cho T, Prasad S, Kojic L, Lu J, Liu Y, Lo E, Zhang S, Wu JZ, Li YP, Wen YH, Imm JH, Cynader MS, Wang YT.

Nat Med. 2009 Dec;15(12):1399-406. doi: 10.1038/nm.2064. Epub 2009 Nov 22.

PMID:
19966780
15.

Akt2 is required for hepatic lipid accumulation in models of insulin resistance.

Leavens KF, Easton RM, Shulman GI, Previs SF, Birnbaum MJ.

Cell Metab. 2009 Nov;10(5):405-18. doi: 10.1016/j.cmet.2009.10.004.

16.

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.

Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F.

J Clin Invest. 2009 May;119(5):1201-15. doi: 10.1172/JCI37007. Epub 2009 Apr 13.

17.

Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples.

Le Hellard S, Mühleisen TW, Djurovic S, Fernø J, Ouriaghi Z, Mattheisen M, Vasilescu C, Raeder MB, Hansen T, Strohmaier J, Georgi A, Brockschmidt FF, Melle I, Nenadic I, Sauer H, Rietschel M, Nöthen MM, Werge T, Andreassen OA, Cichon S, Steen VM.

Mol Psychiatry. 2010 May;15(5):463-72. doi: 10.1038/mp.2008.110. Epub 2008 Oct 21.

PMID:
18936756
18.

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets.

Furuhashi M, Hotamisligil GS.

Nat Rev Drug Discov. 2008 Jun;7(6):489-503. doi: 10.1038/nrd2589. Review.

19.

Protein lipidation meets proteomics.

Meinnel T, Giglione C.

Front Biosci. 2008 May 1;13:6326-40. Review.

PMID:
18508663
20.
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