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Items: 1 to 20 of 46

1.

Biology and pathophysiology of the amyloid precursor protein.

Zheng H, Koo EH.

Mol Neurodegener. 2011 Apr 28;6(1):27. doi: 10.1186/1750-1326-6-27.

2.

Measurement of heme concentration.

Sinclair PR, Gorman N, Jacobs JM.

Curr Protoc Toxicol. 2001 May;Chapter 8:Unit 8.3. doi: 10.1002/0471140856.tx0803s00.

PMID:
20954156
3.

Targeting heme oxygenase-1 for neuroprotection and neuroinflammation in neurodegenerative diseases.

Jazwa A, Cuadrado A.

Curr Drug Targets. 2010 Dec;11(12):1517-31. Review.

PMID:
20704549
4.

Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling.

Ma T, Zhao Y, Kwak YD, Yang Z, Thompson R, Luo Z, Xu H, Liao FF.

J Neurosci. 2009 Sep 9;29(36):11226-36. doi: 10.1523/JNEUROSCI.6150-08.2009.

5.

The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains.

Tamayev R, Zhou D, D'Adamio L.

Mol Neurodegener. 2009 Jul 14;4:28. doi: 10.1186/1750-1326-4-28.

6.

Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia.

Guernsey DL, Jiang H, Campagna DR, Evans SC, Ferguson M, Kellogg MD, Lachance M, Matsuoka M, Nightingale M, Rideout A, Saint-Amant L, Schmidt PJ, Orr A, Bottomley SS, Fleming MD, Ludman M, Dyack S, Fernandez CV, Samuels ME.

Nat Genet. 2009 Jun;41(6):651-3. doi: 10.1038/ng.359. Epub 2009 May 3.

PMID:
19412178
7.

Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.

Louneva N, Cohen JW, Han LY, Talbot K, Wilson RS, Bennett DA, Trojanowski JQ, Arnold SE.

Am J Pathol. 2008 Nov;173(5):1488-95. doi: 10.2353/ajpath.2008.080434. Epub 2008 Sep 25.

8.

Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role.

Giliberto L, Zhou D, Weldon R, Tamagno E, De Luca P, Tabaton M, D'Adamio L.

Mol Neurodegener. 2008 Sep 2;3:12. doi: 10.1186/1750-1326-3-12.

9.

Mitochondrial fragmentation in neurodegeneration.

Knott AB, Perkins G, Schwarzenbacher R, Bossy-Wetzel E.

Nat Rev Neurosci. 2008 Jul;9(7):505-18. doi: 10.1038/nrn2417. Review.

10.

Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism.

Zhang YW, Xu H.

Curr Mol Med. 2007 Nov;7(7):687-96. Review.

PMID:
18045146
11.

The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.

Ring S, Weyer SW, Kilian SB, Waldron E, Pietrzik CU, Filippov MA, Herms J, Buchholz C, Eckman CB, Korte M, Wolfer DP, Müller UC.

J Neurosci. 2007 Jul 18;27(29):7817-26.

12.

Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression.

Zhang YW, Wang R, Liu Q, Zhang H, Liao FF, Xu H.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10613-8. Epub 2007 Jun 7.

13.

Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria.

Pamplona A, Ferreira A, Balla J, Jeney V, Balla G, Epiphanio S, Chora A, Rodrigues CD, Gregoire IP, Cunha-Rodrigues M, Portugal S, Soares MP, Mota MM.

Nat Med. 2007 Jun;13(6):703-10. Epub 2007 May 13.

PMID:
17496899
14.

The intracellular domain of the amyloid precursor protein (AICD) enhances the p53-mediated apoptosis.

Ozaki T, Li Y, Kikuchi H, Tomita T, Iwatsubo T, Nakagawara A.

Biochem Biophys Res Commun. 2006 Dec 8;351(1):57-63. Epub 2006 Oct 9.

PMID:
17054906
15.

Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system.

Haitina T, Lindblom J, Renström T, Fredriksson R.

Genomics. 2006 Dec;88(6):779-90. Epub 2006 Sep 1.

16.
17.

Neuronal apoptosis in neurodegenerative diseases: from basic research to clinical application.

Kermer P, Liman J, Weishaupt JH, Bähr M.

Neurodegener Dis. 2004;1(1):9-19. Review.

PMID:
16908969
18.

Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

Barsoum MJ, Yuan H, Gerencser AA, Liot G, Kushnareva Y, Gräber S, Kovacs I, Lee WD, Waggoner J, Cui J, White AD, Bossy B, Martinou JC, Youle RJ, Lipton SA, Ellisman MH, Perkins GA, Bossy-Wetzel E.

EMBO J. 2006 Aug 23;25(16):3900-11. Epub 2006 Jul 27.

19.

Presenilin-dependent gamma-secretase-mediated control of p53-associated cell death in Alzheimer's disease.

Alves da Costa C, Sunyach C, Pardossi-Piquard R, Sévalle J, Vincent B, Boyer N, Kawarai T, Girardot N, St George-Hyslop P, Checler F.

J Neurosci. 2006 Jun 7;26(23):6377-85.

20.

Apoptosis effector mechanisms: a requiem performed in different keys.

Hail N Jr, Carter BZ, Konopleva M, Andreeff M.

Apoptosis. 2006 Jun;11(6):889-904. Review.

PMID:
16547589
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