Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 164

1.

Early and late steps in telomere overhang processing in normal human cells: the position of the final RNA primer drives telomere shortening.

Chow TT, Zhao Y, Mak SS, Shay JW, Wright WE.

Genes Dev. 2012 Jun 1;26(11):1167-78. doi: 10.1101/gad.187211.112.

PMID:
22661228
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions.

Suram A, Kaplunov J, Patel PL, Ruan H, Cerutti A, Boccardi V, Fumagalli M, Di Micco R, Mirani N, Gurung RL, Hande MP, d'Adda di Fagagna F, Herbig U.

EMBO J. 2012 Jun 29;31(13):2839-51. doi: 10.1038/emboj.2012.132. Epub 2012 May 8.

PMID:
22569128
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence.

Hewitt G, Jurk D, Marques FD, Correia-Melo C, Hardy T, Gackowska A, Anderson R, Taschuk M, Mann J, Passos JF.

Nat Commun. 2012 Feb 28;3:708. doi: 10.1038/ncomms1708.

PMID:
22426229
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation.

Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, Kaplunov JM, Bucci G, Dobreva M, Matti V, Beausejour CM, Herbig U, Longhese MP, d'Adda di Fagagna F.

Nat Cell Biol. 2012 Mar 18;14(4):355-65. doi: 10.1038/ncb2466. Erratum in: Nat Cell Biol. 2012 May;14(5):555.

PMID:
22426077
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.

Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A, Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, Zhang J, Gan B, Perry SR, Jiang S, Li L, Horner JW, Wang YA, Chin L, DePinho RA.

Cell. 2012 Mar 2;148(5):896-907. doi: 10.1016/j.cell.2012.01.039. Epub 2012 Feb 16.

PMID:
22341455
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions.

Tomimatsu N, Mukherjee B, Deland K, Kurimasa A, Bolderson E, Khanna KK, Burma S.

DNA Repair (Amst). 2012 Apr 1;11(4):441-8. doi: 10.1016/j.dnarep.2012.01.006. Epub 2012 Feb 11.

PMID:
22326273
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The genetics of dyskeratosis congenita.

Mason PJ, Bessler M.

Cancer Genet. 2011 Dec;204(12):635-45. doi: 10.1016/j.cancergen.2011.11.002. Review.

PMID:
22285015
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus.

Anderson BH, Kasher PR, Mayer J, Szynkiewicz M, Jenkinson EM, Bhaskar SS, Urquhart JE, Daly SB, Dickerson JE, O'Sullivan J, Leibundgut EO, Muter J, Abdel-Salem GM, Babul-Hirji R, Baxter P, Berger A, Bonafé L, Brunstom-Hernandez JE, Buckard JA, Chitayat D, Chong WK, Cordelli DM, Ferreira P, Fluss J, Forrest EH, Franzoni E, Garone C, Hammans SR, Houge G, Hughes I, Jacquemont S, Jeannet PY, Jefferson RJ, Kumar R, Kutschke G, Lundberg S, Lourenço CM, Mehta R, Naidu S, Nischal KK, Nunes L, Ounap K, Philippart M, Prabhakar P, Risen SR, Schiffmann R, Soh C, Stephenson JB, Stewart H, Stone J, Tolmie JL, van der Knaap MS, Vieira JP, Vilain CN, Wakeling EL, Wermenbol V, Whitney A, Lovell SC, Meyer S, Livingston JH, Baerlocher GM, Black GC, Rice GI, Crow YJ.

Nat Genet. 2012 Jan 22;44(3):338-42. doi: 10.1038/ng.1084.

PMID:
22267198
[PubMed - indexed for MEDLINE]
9.

Human Ku70/80 protein blocks exonuclease 1-mediated DNA resection in the presence of human Mre11 or Mre11/Rad50 protein complex.

Sun J, Lee KJ, Davis AJ, Chen DJ.

J Biol Chem. 2012 Feb 10;287(7):4936-45. doi: 10.1074/jbc.M111.306167. Epub 2011 Dec 15.

PMID:
22179609
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Five dysfunctional telomeres predict onset of senescence in human cells.

Kaul Z, Cesare AJ, Huschtscha LI, Neumann AA, Reddel RR.

EMBO Rep. 2011 Dec 23;13(1):52-9. doi: 10.1038/embor.2011.227.

PMID:
22157895
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Common fragile sites: mechanisms of instability revisited.

Debatisse M, Le Tallec B, Letessier A, Dutrillaux B, Brison O.

Trends Genet. 2012 Jan;28(1):22-32. doi: 10.1016/j.tig.2011.10.003. Epub 2011 Nov 15. Review.

PMID:
22094264
[PubMed - indexed for MEDLINE]
12.

Telomerase and idiopathic pulmonary fibrosis.

Armanios M.

Mutat Res. 2012 Feb 1;730(1-2):52-8. doi: 10.1016/j.mrfmmm.2011.10.013. Epub 2011 Nov 4. Review.

PMID:
22079513
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells.

Reynolds GE, Gao Q, Miller D, Snow BE, Harrington LA, Murnane JP.

DNA Repair (Amst). 2011 Nov 10;10(11):1164-73. doi: 10.1016/j.dnarep.2011.09.002. Epub 2011 Sep 25.

PMID:
21945094
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.

Langerak P, Mejia-Ramirez E, Limbo O, Russell P.

PLoS Genet. 2011 Sep;7(9):e1002271. doi: 10.1371/journal.pgen.1002271. Epub 2011 Sep 8.

PMID:
21931565
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Telomeres and lifestyle factors: roles in cellular aging.

Lin J, Epel E, Blackburn E.

Mutat Res. 2012 Feb 1;730(1-2):85-9. doi: 10.1016/j.mrfmmm.2011.08.003. Epub 2011 Aug 22.

PMID:
21878343
[PubMed - indexed for MEDLINE]
16.

Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway.

Della-Maria J, Zhou Y, Tsai MS, Kuhnlein J, Carney JP, Paull TT, Tomkinson AE.

J Biol Chem. 2011 Sep 30;286(39):33845-53. doi: 10.1074/jbc.M111.274159. Epub 2011 Aug 3.

PMID:
21816818
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Molecular mechanisms generating and stabilizing terminal 22q13 deletions in 44 subjects with Phelan/McDermid syndrome.

Bonaglia MC, Giorda R, Beri S, De Agostini C, Novara F, Fichera M, Grillo L, Galesi O, Vetro A, Ciccone R, Bonati MT, Giglio S, Guerrini R, Osimani S, Marelli S, Zucca C, Grasso R, Borgatti R, Mani E, Motta C, Molteni M, Romano C, Greco D, Reitano S, Baroncini A, Lapi E, Cecconi A, Arrigo G, Patricelli MG, Pantaleoni C, D'Arrigo S, Riva D, Sciacca F, Dalla Bernardina B, Zoccante L, Darra F, Termine C, Maserati E, Bigoni S, Priolo E, Bottani A, Gimelli S, Bena F, Brusco A, di Gregorio E, Bagnasco I, Giussani U, Nitsch L, Politi P, Martinez-Frias ML, Martínez-Fernández ML, Martínez Guardia N, Bremer A, Anderlid BM, Zuffardi O.

PLoS Genet. 2011 Jul;7(7):e1002173. doi: 10.1371/journal.pgen.1002173. Epub 2011 Jul 14.

PMID:
21779178
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Assessment of palindromes as platforms for DNA amplification in breast cancer.

Guenthoer J, Diede SJ, Tanaka H, Chai X, Hsu L, Tapscott SJ, Porter PL.

Genome Res. 2012 Feb;22(2):232-45. doi: 10.1101/gr.117226.110. Epub 2011 Jul 13.

PMID:
21752925
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation.

Simsek D, Brunet E, Wong SY, Katyal S, Gao Y, McKinnon PJ, Lou J, Zhang L, Li J, Rebar EJ, Gregory PD, Holmes MC, Jasin M.

PLoS Genet. 2011 Jun;7(6):e1002080. doi: 10.1371/journal.pgen.1002080. Epub 2011 Jun 2.

PMID:
21655080
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Subtelomeric regions in mammalian cells are deficient in DNA double-strand break repair.

Miller D, Reynolds GE, Mejia R, Stark JM, Murnane JP.

DNA Repair (Amst). 2011 May 5;10(5):536-44. doi: 10.1016/j.dnarep.2011.03.001. Epub 2011 Apr 3.

PMID:
21466975
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk