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mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.

Yilmaz ÖH, Katajisto P, Lamming DW, Gültekin Y, Bauer-Rowe KE, Sengupta S, Birsoy K, Dursun A, Yilmaz VO, Selig M, Nielsen GP, Mino-Kenudson M, Zukerberg LR, Bhan AK, Deshpande V, Sabatini DM.

Nature. 2012 Jun 28;486(7404):490-5. doi: 10.1038/nature11163.


Changes in primary lymphoid organs with aging.

Chinn IK, Blackburn CC, Manley NR, Sempowski GD.

Semin Immunol. 2012 Oct;24(5):309-20. doi: 10.1016/j.smim.2012.04.005. Epub 2012 May 2. Review.


The haematopoietic stem cell niche at a glance.

Lo Celso C, Scadden DT.

J Cell Sci. 2011 Nov 1;124(Pt 21):3529-35. doi: 10.1242/jcs.074112. No abstract available.


Changes in human bone marrow fat content associated with changes in hematopoietic stem cell numbers and cytokine levels with aging.

Tuljapurkar SR, McGuire TR, Brusnahan SK, Jackson JD, Garvin KL, Kessinger MA, Lane JT, O' Kane BJ, Sharp JG.

J Anat. 2011 Nov;219(5):574-81. doi: 10.1111/j.1469-7580.2011.01423.x. Epub 2011 Sep 16.


Age-related changes in human hematopoietic stem/progenitor cells.

Kuranda K, Vargaftig J, de la Rochere P, Dosquet C, Charron D, Bardin F, Tonnelle C, Bonnet D, Goodhardt M.

Aging Cell. 2011 Jun;10(3):542-6. doi: 10.1111/j.1474-9726.2011.00675.x. Epub 2011 Mar 22.


Failure of the stem cell niche rather than loss of oocyte stem cells in the aging ovary.

Massasa E, Costa XS, Taylor HS.

Aging (Albany NY). 2010 Jan 26;2(1):1-2. Review. No abstract available.


Modeling of replicative senescence in hematopoietic development.

Marciniak-Czochra A, Stiehl T, Wagner W.

Aging (Albany NY). 2009 Jul 23;1(8):723-32.


Declining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involution.

Sun L, Guo J, Brown R, Amagai T, Zhao Y, Su DM.

Aging Cell. 2010 Jun;9(3):347-57. doi: 10.1111/j.1474-9726.2010.00559.x. Epub 2010 Mar 12.


Mechanisms of hematopoietic stem cell aging.

Ergen AV, Goodell MA.

Exp Gerontol. 2010 Apr;45(4):286-90. doi: 10.1016/j.exger.2009.12.010. Epub 2009 Dec 23.


mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.

Chen C, Liu Y, Liu Y, Zheng P.

Sci Signal. 2009 Nov 24;2(98):ra75. doi: 10.1126/scisignal.2000559.


Age-associated declines in immune system development and function: causes, consequences, and reversal.

Dorshkind K, Swain S.

Curr Opin Immunol. 2009 Aug;21(4):404-7. doi: 10.1016/j.coi.2009.07.001. Epub 2009 Jul 23. No abstract available.


Aging in the lympho-hematopoietic stem cell compartment.

Geiger H, Rudolph KL.

Trends Immunol. 2009 Jul;30(7):360-5. doi: 10.1016/ Epub 2009 Jun 18. Review.


Effects of aging on hematopoietic stem and progenitor cells.

Waterstrat A, Van Zant G.

Curr Opin Immunol. 2009 Aug;21(4):408-13. doi: 10.1016/j.coi.2009.05.002. Epub 2009 Jun 6. Review.


Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones.

Köhler A, Schmithorst V, Filippi MD, Ryan MA, Daria D, Gunzer M, Geiger H.

Blood. 2009 Jul 9;114(2):290-8. doi: 10.1182/blood-2008-12-195644. Epub 2009 Apr 8.


Hematopoietic stem cell transplantation without irradiation.

Waskow C, Madan V, Bartels S, Costa C, Blasig R, Rodewald HR.

Nat Methods. 2009 Apr;6(4):267-9. doi: 10.1038/nmeth.1309. Epub 2009 Mar 8.


Aging, stem cells, and mammalian target of rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells.

Blagosklonny MV.

Rejuvenation Res. 2008 Aug;11(4):801-8. doi: 10.1089/rej.2008.0722. Review.


Aging of hematopoietic stem cells is regulated by the stem cell niche.

Wagner W, Horn P, Bork S, Ho AD.

Exp Gerontol. 2008 Nov;43(11):974-80. doi: 10.1016/j.exger.2008.04.007. Epub 2008 Apr 22. Review.


Stem cell review series: aging of the skeletal muscle stem cell niche.

Gopinath SD, Rando TA.

Aging Cell. 2008 Aug;7(4):590-8. doi: 10.1111/j.1474-9726.2008.00399.x. Epub 2008 Jun 28. Review.


Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testis.

Boyle M, Wong C, Rocha M, Jones DL.

Cell Stem Cell. 2007 Oct 11;1(4):470-8. doi: 10.1016/j.stem.2007.08.002.

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