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Results: 1 to 20 of 68

1.

Recurrent R-spondin fusions in colon cancer.

Seshagiri S, Stawiski EW, Durinck S, Modrusan Z, Storm EE, Conboy CB, Chaudhuri S, Guan Y, Janakiraman V, Jaiswal BS, Guillory J, Ha C, Dijkgraaf GJ, Stinson J, Gnad F, Huntley MA, Degenhardt JD, Haverty PM, Bourgon R, Wang W, Koeppen H, Gentleman R, Starr TK, Zhang Z, Largaespada DA, Wu TD, de Sauvage FJ.

Nature. 2012 Aug 30;488(7413):660-4. doi: 10.1038/nature11282.

PMID:
22895193
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Matrix metalloproteinase induction of Rac1b, a key effector of lung cancer progression.

Stallings-Mann ML, Waldmann J, Zhang Y, Miller E, Gauthier ML, Visscher DW, Downey GP, Radisky ES, Fields AP, Radisky DC.

Sci Transl Med. 2012 Jul 11;4(142):142ra95. doi: 10.1126/scitranslmed.3004062.

PMID:
22786680
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, Morais P, Meltzer J, Korejwa A, Jané-Valbuena J, Mapa FA, Thibault J, Bric-Furlong E, Raman P, Shipway A, Engels IH, Cheng J, Yu GK, Yu J, Aspesi P Jr, de Silva M, Jagtap K, Jones MD, Wang L, Hatton C, Palescandolo E, Gupta S, Mahan S, Sougnez C, Onofrio RC, Liefeld T, MacConaill L, Winckler W, Reich M, Li N, Mesirov JP, Gabriel SB, Getz G, Ardlie K, Chan V, Myer VE, Weber BL, Porter J, Warmuth M, Finan P, Harris JL, Meyerson M, Golub TR, Morrissey MP, Sellers WR, Schlegel R, Garraway LA.

Nature. 2012 Mar 28;483(7391):603-7. doi: 10.1038/nature11003. Erratum in: Nature. 2012 Dec 13;492(7428):290.

PMID:
22460905
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Systematic identification of genomic markers of drug sensitivity in cancer cells.

Garnett MJ, Edelman EJ, Heidorn SJ, Greenman CD, Dastur A, Lau KW, Greninger P, Thompson IR, Luo X, Soares J, Liu Q, Iorio F, Surdez D, Chen L, Milano RJ, Bignell GR, Tam AT, Davies H, Stevenson JA, Barthorpe S, Lutz SR, Kogera F, Lawrence K, McLaren-Douglas A, Mitropoulos X, Mironenko T, Thi H, Richardson L, Zhou W, Jewitt F, Zhang T, O'Brien P, Boisvert JL, Price S, Hur W, Yang W, Deng X, Butler A, Choi HG, Chang JW, Baselga J, Stamenkovic I, Engelman JA, Sharma SV, Delattre O, Saez-Rodriguez J, Gray NS, Settleman J, Futreal PA, Haber DA, Stratton MR, Ramaswamy S, McDermott U, Benes CH.

Nature. 2012 Mar 28;483(7391):570-5. doi: 10.1038/nature11005.

PMID:
22460902
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Drug discovery: Cell lines battle cancer.

Weinstein JN.

Nature. 2012 Mar 28;483(7391):544-5. doi: 10.1038/483544a. No abstract available.

PMID:
22460893
[PubMed - indexed for MEDLINE]
6.

The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis.

Zhou C, Licciulli S, Avila JL, Cho M, Troutman S, Jiang P, Kossenkov AV, Showe LC, Liu Q, Vachani A, Albelda SM, Kissil JL.

Oncogene. 2013 Feb 14;32(7):903-9. doi: 10.1038/onc.2012.99. Epub 2012 Mar 19.

PMID:
22430205
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Clonal selection drives genetic divergence of metastatic medulloblastoma.

Wu X, Northcott PA, Dubuc A, Dupuy AJ, Shih DJ, Witt H, Croul S, Bouffet E, Fults DW, Eberhart CG, Garzia L, Van Meter T, Zagzag D, Jabado N, Schwartzentruber J, Majewski J, Scheetz TE, Pfister SM, Korshunov A, Li XN, Scherer SW, Cho YJ, Akagi K, MacDonald TJ, Koster J, McCabe MG, Sarver AL, Collins VP, Weiss WA, Largaespada DA, Collier LS, Taylor MD.

Nature. 2012 Feb 15;482(7386):529-33. doi: 10.1038/nature10825.

PMID:
22343890
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients.

Jiang Z, Jhunjhunwala S, Liu J, Haverty PM, Kennemer MI, Guan Y, Lee W, Carnevali P, Stinson J, Johnson S, Diao J, Yeung S, Jubb A, Ye W, Wu TD, Kapadia SB, de Sauvage FJ, Gentleman RC, Stern HM, Seshagiri S, Pant KP, Modrusan Z, Ballinger DG, Zhang Z.

Genome Res. 2012 Apr;22(4):593-601. doi: 10.1101/gr.133926.111. Epub 2012 Jan 20.

PMID:
22267523
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cancer statistics, 2012.

Siegel R, Naishadham D, Jemal A.

CA Cancer J Clin. 2012 Jan-Feb;62(1):10-29. doi: 10.3322/caac.20138. Epub 2012 Jan 4.

PMID:
22237781
[PubMed - indexed for MEDLINE]
Free Article
10.

Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency.

Wang L, Tsutsumi S, Kawaguchi T, Nagasaki K, Tatsuno K, Yamamoto S, Sang F, Sonoda K, Sugawara M, Saiura A, Hirono S, Yamaue H, Miki Y, Isomura M, Totoki Y, Nagae G, Isagawa T, Ueda H, Murayama-Hosokawa S, Shibata T, Sakamoto H, Kanai Y, Kaneda A, Noda T, Aburatani H.

Genome Res. 2012 Feb;22(2):208-19. doi: 10.1101/gr.123109.111. Epub 2011 Dec 7.

PMID:
22156295
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The effect of adenovirus-mediated gene expression of FHIT in small cell lung cancer cells.

Zandi R, Xu K, Poulsen HS, Roth JA, Ji L.

Cancer Invest. 2011 Dec;29(10):683-91. doi: 10.3109/07357907.2011.626475.

PMID:
22085272
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer.

Wang K, Kan J, Yuen ST, Shi ST, Chu KM, Law S, Chan TL, Kan Z, Chan AS, Tsui WY, Lee SP, Ho SL, Chan AK, Cheng GH, Roberts PC, Rejto PA, Gibson NW, Pocalyko DJ, Mao M, Xu J, Leung SY.

Nat Genet. 2011 Oct 30;43(12):1219-23. doi: 10.1038/ng.982.

PMID:
22037554
[PubMed - indexed for MEDLINE]
13.

A decade of exploring the cancer epigenome - biological and translational implications.

Baylin SB, Jones PA.

Nat Rev Cancer. 2011 Sep 23;11(10):726-34. doi: 10.1038/nrc3130. Review.

PMID:
21941284
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

ChimeraScan: a tool for identifying chimeric transcription in sequencing data.

Iyer MK, Chinnaiyan AM, Maher CA.

Bioinformatics. 2011 Oct 15;27(20):2903-4. doi: 10.1093/bioinformatics/btr467. Epub 2011 Aug 11.

PMID:
21840877
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Adenosine-to-inosine RNA editing meets cancer.

Dominissini D, Moshitch-Moshkovitz S, Amariglio N, Rechavi G.

Carcinogenesis. 2011 Nov;32(11):1569-77. doi: 10.1093/carcin/bgr124. Epub 2011 Jun 29. Review.

PMID:
21715563
[PubMed - indexed for MEDLINE]
Free Article
16.

Exome sequencing reveals comprehensive genomic alterations across eight cancer cell lines.

Chang H, Jackson DG, Kayne PS, Ross-Macdonald PB, Ryseck RP, Siemers NO.

PLoS One. 2011;6(6):e21097. doi: 10.1371/journal.pone.0021097. Epub 2011 Jun 20.

PMID:
21701589
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers.

Mermel CH, Schumacher SE, Hill B, Meyerson ML, Beroukhim R, Getz G.

Genome Biol. 2011;12(4):R41. doi: 10.1186/gb-2011-12-4-r41. Epub 2011 Apr 28.

PMID:
21527027
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Personalized treatment of lung cancer.

Salgia R, Hensing T, Campbell N, Salama AK, Maitland M, Hoffman P, Villaflor V, Vokes EE.

Semin Oncol. 2011 Apr;38(2):274-83. doi: 10.1053/j.seminoncol.2011.01.012. Review.

PMID:
21421117
[PubMed - indexed for MEDLINE]
19.

Cancer epigenetics reaches mainstream oncology.

Rodríguez-Paredes M, Esteller M.

Nat Med. 2011 Mar;17(3):330-9. doi: 10.1038/nm.2305. Review.

PMID:
21386836
[PubMed - indexed for MEDLINE]
20.

The genetic landscape of the childhood cancer medulloblastoma.

Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.

Science. 2011 Jan 28;331(6016):435-9. doi: 10.1126/science.1198056. Epub 2010 Dec 16.

PMID:
21163964
[PubMed - indexed for MEDLINE]
Free PMC Article

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