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Results: 1 to 20 of 34

1.

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, Morais P, Meltzer J, Korejwa A, Jané-Valbuena J, Mapa FA, Thibault J, Bric-Furlong E, Raman P, Shipway A, Engels IH, Cheng J, Yu GK, Yu J, Aspesi P Jr, de Silva M, Jagtap K, Jones MD, Wang L, Hatton C, Palescandolo E, Gupta S, Mahan S, Sougnez C, Onofrio RC, Liefeld T, MacConaill L, Winckler W, Reich M, Li N, Mesirov JP, Gabriel SB, Getz G, Ardlie K, Chan V, Myer VE, Weber BL, Porter J, Warmuth M, Finan P, Harris JL, Meyerson M, Golub TR, Morrissey MP, Sellers WR, Schlegel R, Garraway LA.

Nature. 2012 Mar 28;483(7391):603-7. doi: 10.1038/nature11003. Erratum in: Nature. 2012 Dec 13;492(7428):290.

PMID:
22460905
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mechanisms decreasing in vitro susceptibility to the LpxC inhibitor CHIR-090 in the gram-negative pathogen Pseudomonas aeruginosa.

Caughlan RE, Jones AK, Delucia AM, Woods AL, Xie L, Ma B, Barnes SW, Walker JR, Sprague ER, Yang X, Dean CR.

Antimicrob Agents Chemother. 2012 Jan;56(1):17-27. doi: 10.1128/AAC.05417-11. Epub 2011 Oct 24.

PMID:
22024823
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Data processing and analysis with the autoPROC toolbox.

Vonrhein C, Flensburg C, Keller P, Sharff A, Smart O, Paciorek W, Womack T, Bricogne G.

Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):293-302. doi: 10.1107/S0907444911007773. Epub 2011 Mar 18.

PMID:
21460447
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The ribosome as a molecular machine: the mechanism of tRNA-mRNA movement in translocation.

Rodnina MV, Wintermeyer W.

Biochem Soc Trans. 2011 Apr;39(2):658-62. doi: 10.1042/BST0390658. Review.

PMID:
21428957
[PubMed - indexed for MEDLINE]
5.

Molecular dynamics of EF-G during translocation.

Li W, Trabuco LG, Schulten K, Frank J.

Proteins. 2011 May;79(5):1478-86. doi: 10.1002/prot.22976. Epub 2011 Mar 1.

PMID:
21365677
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Staphylococcus aureus elongation factor G--structure and analysis of a target for fusidic acid.

Chen Y, Koripella RK, Sanyal S, Selmer M.

FEBS J. 2010 Sep;277(18):3789-803. doi: 10.1111/j.1742-4658.2010.07780.x. Epub 2010 Aug 13.

PMID:
20718859
[PubMed - indexed for MEDLINE]
7.

A survey of yeast genomic assays for drug and target discovery.

Smith AM, Ammar R, Nislow C, Giaever G.

Pharmacol Ther. 2010 Aug;127(2):156-64. doi: 10.1016/j.pharmthera.2010.04.012. Epub 2010 May 28. Review.

PMID:
20546776
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Elucidation of the structure and intermolecular interactions of a reversible cyclic-peptide inhibitor of the proteasome by NMR spectroscopy and molecular modeling.

Stauch B, Simon B, Basile T, Schneider G, Malek NP, Kalesse M, Carlomagno T.

Angew Chem Int Ed Engl. 2010 May 25;49(23):3934-8. doi: 10.1002/anie.201000140. No abstract available.

PMID:
20408152
[PubMed - indexed for MEDLINE]
9.

Mitochondrial translation and beyond: processes implicated in combined oxidative phosphorylation deficiencies.

Smits P, Smeitink J, van den Heuvel L.

J Biomed Biotechnol. 2010;2010:737385. doi: 10.1155/2010/737385. Epub 2010 Apr 13. Review.

PMID:
20396601
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Features and development of Coot.

Emsley P, Lohkamp B, Scott WG, Cowtan K.

Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501. doi: 10.1107/S0907444910007493. Epub 2010 Mar 24.

PMID:
20383002
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Synthesis and biological characterization of argyrin F.

Bülow L, Nickeleit I, Girbig AK, Brodmann T, Rentsch A, Eggert U, Sasse F, Steinmetz H, Frank R, Carlomagno T, Malek NP, Kalesse M.

ChemMedChem. 2010 Jun 7;5(6):832-6. doi: 10.1002/cmdc.201000080. No abstract available. Erratum in: ChemMedChem. 2010 Jun 7;5(6):805.

PMID:
20358576
[PubMed - indexed for MEDLINE]
12.

XDS.

Kabsch W.

Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):125-32. doi: 10.1107/S0907444909047337. Epub 2010 Jan 22.

PMID:
20124692
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The structure of the ribosome with elongation factor G trapped in the posttranslocational state.

Gao YG, Selmer M, Dunham CM, Weixlbaumer A, Kelley AC, Ramakrishnan V.

Science. 2009 Oct 30;326(5953):694-9. doi: 10.1126/science.1179709.

PMID:
19833919
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Phaser crystallographic software.

McCoy AJ, Grosse-Kunstleve RW, Adams PD, Winn MD, Storoni LC, Read RJ.

J Appl Crystallogr. 2007 Aug 1;40(Pt 4):658-674. Epub 2007 Jul 13.

PMID:
19461840
[PubMed]
Free PMC Article
15.

Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition.

Nickeleit I, Zender S, Sasse F, Geffers R, Brandes G, Sörensen I, Steinmetz H, Kubicka S, Carlomagno T, Menche D, Gütgemann I, Buer J, Gossler A, Manns MP, Kalesse M, Frank R, Malek NP.

Cancer Cell. 2008 Jul 8;14(1):23-35. doi: 10.1016/j.ccr.2008.05.016.

PMID:
18598941
[PubMed - indexed for MEDLINE]
Free Article
16.

A novel role for a familiar protein in apoptosis induced by proteasome inhibition.

McConkey DJ.

Cancer Cell. 2008 Jul 8;14(1):1-2. doi: 10.1016/j.ccr.2008.06.011.

PMID:
18598936
[PubMed - indexed for MEDLINE]
Free Article
17.

EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition.

Seo HS, Abedin S, Kamp D, Wilson DN, Nierhaus KH, Cooperman BS.

Biochemistry. 2006 Feb 28;45(8):2504-14.

PMID:
16489743
[PubMed - indexed for MEDLINE]
18.

Structural insights into fusidic acid resistance and sensitivity in EF-G.

Hansson S, Singh R, Gudkov AT, Liljas A, Logan DT.

J Mol Biol. 2005 May 13;348(4):939-49.

PMID:
15843024
[PubMed - indexed for MEDLINE]
19.

Global analysis of protein localization in budding yeast.

Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK.

Nature. 2003 Oct 16;425(6959):686-91.

PMID:
14562095
[PubMed - indexed for MEDLINE]
Free Article
20.

Argyrins, immunosuppressive cyclic peptides from myxobacteria. II. Structure elucidation and stereochemistry.

Vollbrecht L, Steinmetz H, Hofle G, Oberer L, Rihs G, Bovermann G, von Matt P.

J Antibiot (Tokyo). 2002 Aug;55(8):715-21.

PMID:
12374385
[PubMed - indexed for MEDLINE]
Free Article

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