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Items: 1 to 20 of 49

1.

Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification.

Samstein RM, Arvey A, Josefowicz SZ, Peng X, Reynolds A, Sandstrom R, Neph S, Sabo P, Kim JM, Liao W, Li MO, Leslie C, Stamatoyannopoulos JA, Rudensky AY.

Cell. 2012 Sep 28;151(1):153-66. doi: 10.1016/j.cell.2012.06.053.

2.

The Stat3/GR interaction code: predictive value of direct/indirect DNA recruitment for transcription outcome.

Langlais D, Couture C, Balsalobre A, Drouin J.

Mol Cell. 2012 Jul 13;47(1):38-49. doi: 10.1016/j.molcel.2012.04.021. Epub 2012 May 24.

3.

Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency.

Bettini ML, Pan F, Bettini M, Finkelstein D, Rehg JE, Floess S, Bell BD, Ziegler SF, Huehn J, Pardoll DM, Vignali DA.

Immunity. 2012 May 25;36(5):717-30. doi: 10.1016/j.immuni.2012.03.020. Epub 2012 May 10.

4.

An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes.

Darce J, Rudra D, Li L, Nishio J, Cipolletta D, Rudensky AY, Mathis D, Benoist C.

Immunity. 2012 May 25;36(5):731-41. doi: 10.1016/j.immuni.2012.04.007. Epub 2012 May 10.

5.

Regulatory T cells: mechanisms of differentiation and function.

Josefowicz SZ, Lu LF, Rudensky AY.

Annu Rev Immunol. 2012;30:531-64. doi: 10.1146/annurev.immunol.25.022106.141623. Epub 2012 Jan 6. Review.

PMID:
22224781
6.

GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in mice.

Wohlfert EA, Grainger JR, Bouladoux N, Konkel JE, Oldenhove G, Ribeiro CH, Hall JA, Yagi R, Naik S, Bhairavabhotla R, Paul WE, Bosselut R, Wei G, Zhao K, Oukka M, Zhu J, Belkaid Y.

J Clin Invest. 2011 Nov;121(11):4503-15. doi: 10.1172/JCI57456. Epub 2011 Oct 3.

7.

An essential role of the transcription factor GATA-3 for the function of regulatory T cells.

Wang Y, Su MA, Wan YY.

Immunity. 2011 Sep 23;35(3):337-48. doi: 10.1016/j.immuni.2011.08.012. Epub 2011 Sep 15.

8.

Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease.

Vanvalkenburgh J, Albu DI, Bapanpally C, Casanova S, Califano D, Jones DM, Ignatowicz L, Kawamoto S, Fagarasan S, Jenkins NA, Copeland NG, Liu P, Avram D.

J Exp Med. 2011 Sep 26;208(10):2069-81. doi: 10.1084/jem.20102683. Epub 2011 Aug 29.

9.

Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.

Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, Zheng Y, Bordman Z, Fu J, Kim Y, Yen HR, Luo W, Zeller K, Shimoda L, Topalian SL, Semenza GL, Dang CV, Pardoll DM, Pan F.

Cell. 2011 Sep 2;146(5):772-84. doi: 10.1016/j.cell.2011.07.033. Epub 2011 Aug 25.

10.

Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types.

Wei G, Abraham BJ, Yagi R, Jothi R, Cui K, Sharma S, Narlikar L, Northrup DL, Tang Q, Paul WE, Zhu J, Zhao K.

Immunity. 2011 Aug 26;35(2):299-311. doi: 10.1016/j.immuni.2011.08.007.

11.

Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I.

Xu L, Kitani A, Stuelten C, McGrady G, Fuss I, Strober W.

Immunity. 2010 Sep 24;33(3):313-25. doi: 10.1016/j.immuni.2010.09.001.

12.

The Ets-1 transcription factor controls the development and function of natural regulatory T cells.

Mouly E, Chemin K, Nguyen HV, Chopin M, Mesnard L, Leite-de-Moraes M, Burlen-defranoux O, Bandeira A, Bories JC.

J Exp Med. 2010 Sep 27;207(10):2113-25. doi: 10.1084/jem.20092153. Epub 2010 Sep 20.

13.

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

Pardo M, Lang B, Yu L, Prosser H, Bradley A, Babu MM, Choudhary J.

Cell Stem Cell. 2010 Apr 2;6(4):382-95. doi: 10.1016/j.stem.2010.03.004.

14.

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate.

Zheng Y, Josefowicz S, Chaudhry A, Peng XP, Forbush K, Rudensky AY.

Nature. 2010 Feb 11;463(7282):808-12. doi: 10.1038/nature08750. Epub 2010 Jan 13.

15.

Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome.

Ruan Q, Kameswaran V, Tone Y, Li L, Liou HC, Greene MI, Tone M, Chen YH.

Immunity. 2009 Dec 18;31(6):932-40. doi: 10.1016/j.immuni.2009.10.006.

16.

Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells.

Klunker S, Chong MM, Mantel PY, Palomares O, Bassin C, Ziegler M, Rückert B, Meiler F, Akdis M, Littman DR, Akdis CA.

J Exp Med. 2009 Nov 23;206(12):2701-15. doi: 10.1084/jem.20090596. Epub 2009 Nov 16.

17.

Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells.

Kitoh A, Ono M, Naoe Y, Ohkura N, Yamaguchi T, Yaguchi H, Kitabayashi I, Tsukada T, Nomura T, Miyachi Y, Taniuchi I, Sakaguchi S.

Immunity. 2009 Oct 16;31(4):609-20. doi: 10.1016/j.immuni.2009.09.003. Epub 2009 Oct 1.

18.

CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

Chaudhry A, Rudra D, Treuting P, Samstein RM, Liang Y, Kas A, Rudensky AY.

Science. 2009 Nov 13;326(5955):986-91. doi: 10.1126/science.1172702. Epub 2009 Oct 1.

19.

Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells.

Rudra D, Egawa T, Chong MM, Treuting P, Littman DR, Rudensky AY.

Nat Immunol. 2009 Nov;10(11):1170-7. doi: 10.1038/ni.1795. Epub 2009 Sep 20.

20.

Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells.

Pan F, Yu H, Dang EV, Barbi J, Pan X, Grosso JF, Jinasena D, Sharma SM, McCadden EM, Getnet D, Drake CG, Liu JO, Ostrowski MC, Pardoll DM.

Science. 2009 Aug 28;325(5944):1142-6. doi: 10.1126/science.1176077. Epub 2009 Aug 20.

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