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Classically activated macrophages use stable microtubules for matrix metalloproteinase-9 (MMP-9) secretion.

Hanania R, Sun HS, Xu K, Pustylnik S, Jeganathan S, Harrison RE.

J Biol Chem. 2012 Mar 9;287(11):8468-83. doi: 10.1074/jbc.M111.290676. Epub 2012 Jan 23.


Molecular mechanism of myosin Va recruitment to dense core secretory granules.

Brozzi F, Diraison F, Lajus S, Rajatileka S, Philips T, Regazzi R, Fukuda M, Verkade P, Molnár E, Váradi A.

Traffic. 2012 Jan;13(1):54-69. doi: 10.1111/j.1600-0854.2011.01301.x. Epub 2011 Nov 14.


Release of TNF-α from macrophages is mediated by small GTPase Rab37.

Mori R, Ikematsu K, Kitaguchi T, Kim SE, Okamoto M, Chiba T, Miyawaki A, Shimokawa I, Tsuboi T.

Eur J Immunol. 2011 Nov;41(11):3230-9. doi: 10.1002/eji.201141640. Epub 2011 Sep 12.


Loss of granuphilin and loss of syntaxin-1A cause differential effects on insulin granule docking and fusion.

Wang H, Ishizaki R, Kobayashi E, Fujiwara T, Akagawa K, Izumi T.

J Biol Chem. 2011 Sep 16;286(37):32244-50. doi: 10.1074/jbc.M111.268631. Epub 2011 Jul 18.


Myosin Va acts in concert with Rab27a and MyRIP to regulate acute von-Willebrand factor release from endothelial cells.

Rojo Pulido I, Nightingale TD, Darchen F, Seabra MC, Cutler DF, Gerke V.

Traffic. 2011 Oct;12(10):1371-82. doi: 10.1111/j.1600-0854.2011.01248.x. Epub 2011 Aug 5.


Rab27a targeting to melanosomes requires nucleotide exchange but not effector binding.

Tarafder AK, Wasmeier C, Figueiredo AC, Booth AE, Orihara A, Ramalho JS, Hume AN, Seabra MC.

Traffic. 2011 Aug;12(8):1056-66. doi: 10.1111/j.1600-0854.2011.01216.x. Epub 2011 Jun 15.


TBC proteins: GAPs for mammalian small GTPase Rab?

Fukuda M.

Biosci Rep. 2011 Jun;31(3):159-68. doi: 10.1042/BSR20100112. Review.


VAMP3 is associated with endothelial weibel-palade bodies and participates in their Ca(2+)-dependent exocytosis.

Pulido IR, Jahn R, Gerke V.

Biochim Biophys Acta. 2011 May;1813(5):1038-44. doi: 10.1016/j.bbamcr.2010.11.007. Epub 2010 Nov 20.


Roles of myosin Va and Rab3D in membrane remodeling of immature secretory granules.

Kögel T, Gerdes HH.

Cell Mol Neurobiol. 2010 Nov;30(8):1303-8. doi: 10.1007/s10571-010-9597-6. Epub 2010 Nov 16.


A role for Rab10 in von Willebrand factor release discovered by an AP-1 interactor screen in C. elegans.

Michaux G, Dyer CE, Nightingale TD, Gallaud E, Nurrish S, Cutler DF.

J Thromb Haemost. 2011 Feb;9(2):392-401. doi: 10.1111/j.1538-7836.2010.04138.x.


Protein mobilities and P-selectin storage in Weibel-Palade bodies.

Kiskin NI, Hellen N, Babich V, Hewlett L, Knipe L, Hannah MJ, Carter T.

J Cell Sci. 2010 Sep 1;123(Pt 17):2964-75. doi: 10.1242/jcs.073593. Erratum in: J Cell Sci. 2010 Oct 1;123(Pt 19):3412.


A revised model for the secretion of tPA and cytokines from cultured endothelial cells.

Knipe L, Meli A, Hewlett L, Bierings R, Dempster J, Skehel P, Hannah MJ, Carter T.

Blood. 2010 Sep 23;116(12):2183-91. doi: 10.1182/blood-2010-03-276170. Epub 2010 Jun 10.


Age-dependent preferential dense-core vesicle exocytosis in neuroendocrine cells revealed by newly developed monomeric fluorescent timer protein.

Tsuboi T, Kitaguchi T, Karasawa S, Fukuda M, Miyawaki A.

Mol Biol Cell. 2010 Jan 1;21(1):87-94. doi: 10.1091/mbc.E09-08-0722. Epub 2009 Nov 4.


Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells.

Nightingale TD, Pattni K, Hume AN, Seabra MC, Cutler DF.

Blood. 2009 May 14;113(20):5010-8. doi: 10.1182/blood-2008-09-181206. Epub 2009 Mar 6. Erratum in: Blood. 2011 Mar 24;117(12):3476.


Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells.

Disse J, Vitale N, Bader MF, Gerke V.

Blood. 2009 Jan 22;113(4):973-80. doi: 10.1182/blood-2008-06-165282. Epub 2008 Oct 22.


The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines.

Kimura T, Kaneko Y, Yamada S, Ishihara H, Senda T, Iwamatsu A, Niki I.

J Cell Sci. 2008 Sep 15;121(Pt 18):3092-8. doi: 10.1242/jcs.030544.


Regulation of secretory vesicle traffic by Rab small GTPases.

Fukuda M.

Cell Mol Life Sci. 2008 Sep;65(18):2801-13. doi: 10.1007/s00018-008-8351-4. Review.


Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes.

Figueiredo AC, Wasmeier C, Tarafder AK, Ramalho JS, Baron RA, Seabra MC.

J Biol Chem. 2008 Aug 22;283(34):23209-16. doi: 10.1074/jbc.M804134200. Epub 2008 Jun 17.


Basal secretion of von Willebrand factor from human endothelial cells.

Giblin JP, Hewlett LJ, Hannah MJ.

Blood. 2008 Aug 15;112(4):957-64. doi: 10.1182/blood-2007-12-130740. Epub 2008 Mar 14.


Munc 18-1 and granuphilin collaborate during insulin granule exocytosis.

Tomas A, Meda P, Regazzi R, Pessin JE, Halban PA.

Traffic. 2008 May;9(5):813-32. doi: 10.1111/j.1600-0854.2008.00709.x. Epub 2008 Jan 19.

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