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Endothelial and perivascular cells maintain haematopoietic stem cells.

Ding L, Saunders TL, Enikolopov G, Morrison SJ.

Nature. 2012 Jan 25;481(7382):457-62. doi: 10.1038/nature10783.


Osteoblastic expansion induced by parathyroid hormone receptor signaling in murine osteocytes is not sufficient to increase hematopoietic stem cells.

Calvi LM, Bromberg O, Rhee Y, Weber JM, Smith JN, Basil MJ, Frisch BJ, Bellido T.

Blood. 2012 Mar 15;119(11):2489-99. doi: 10.1182/blood-2011-06-360933. Epub 2012 Jan 18.


Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor.

Kazakia GJ, Speer D, Shanbhag S, Majumdar S, Conklin BR, Nissenson RA, Hsiao EC.

Calcif Tissue Int. 2011 Jul;89(1):10-20. doi: 10.1007/s00223-011-9487-z. Epub 2011 Apr 28.


Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies.

Warr MR, Pietras EM, Passegué E.

Wiley Interdiscip Rev Syst Biol Med. 2011 Nov-Dec;3(6):681-701. doi: 10.1002/wsbm.145. Epub 2011 Mar 15. Review.


The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche.

Omatsu Y, Sugiyama T, Kohara H, Kondoh G, Fujii N, Kohno K, Nagasawa T.

Immunity. 2010 Sep 24;33(3):387-99. doi: 10.1016/j.immuni.2010.08.017.


Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

Winkler IG, Sims NA, Pettit AR, Barbier V, Nowlan B, Helwani F, Poulton IJ, van Rooijen N, Alexander KA, Raggatt LJ, Lévesque JP.

Blood. 2010 Dec 2;116(23):4815-28. doi: 10.1182/blood-2009-11-253534. Epub 2010 Aug 16.


Mesenchymal and haematopoietic stem cells form a unique bone marrow niche.

Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS.

Nature. 2010 Aug 12;466(7308):829-34. doi: 10.1038/nature09262.


Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function.

Chitteti BR, Cheng YH, Streicher DA, Rodriguez-Rodriguez S, Carlesso N, Srour EF, Kacena MA.

J Cell Biochem. 2010 Oct 1;111(2):284-94. doi: 10.1002/jcb.22694.


Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches.

Winkler IG, Barbier V, Wadley R, Zannettino AC, Williams S, Lévesque JP.

Blood. 2010 Jul 22;116(3):375-85. doi: 10.1182/blood-2009-07-233437. Epub 2010 Apr 14.


Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.

Raaijmakers MH, Mukherjee S, Guo S, Zhang S, Kobayashi T, Schoonmaker JA, Ebert BL, Al-Shahrour F, Hasserjian RP, Scadden EO, Aung Z, Matza M, Merkenschlager M, Lin C, Rommens JM, Scadden DT.

Nature. 2010 Apr 8;464(7290):852-7. doi: 10.1038/nature08851. Epub 2010 Mar 21.


Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.

Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, Witte L, May C, Shawber C, Kimura Y, Kitajewski J, Rosenwaks Z, Bernstein ID, Rafii S.

Cell Stem Cell. 2010 Mar 5;6(3):251-64. doi: 10.1016/j.stem.2010.02.001.


JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.

Santaguida M, Schepers K, King B, Sabnis AJ, Forsberg EC, Attema JL, Braun BS, Passegué E.

Cancer Cell. 2009 Apr 7;15(4):341-52. doi: 10.1016/j.ccr.2009.02.016.


Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways.

Wu JY, Purton LE, Rodda SJ, Chen M, Weinstein LS, McMahon AP, Scadden DT, Kronenberg HM.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16976-81. doi: 10.1073/pnas.0802898105. Epub 2008 Oct 28.


Engineering GPCR signaling pathways with RASSLs.

Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL.

Nat Methods. 2008 Aug;5(8):673-8. doi: 10.1038/nmeth.1232. Review.


Platelet dysfunction and increased bleeding tendency in McCune-Albright syndrome.

Bajpai A, Greenway A, Zacharin M.

J Pediatr. 2008 Aug;153(2):287-9. doi: 10.1016/j.jpeds.2008.02.045.


Parathyroid hormone effectively induces mobilization of progenitor cells without depletion of bone marrow.

Brunner S, Zaruba MM, Huber B, David R, Vallaster M, Assmann G, Mueller-Hoecker J, Franz WM.

Exp Hematol. 2008 Sep;36(9):1157-66. doi: 10.1016/j.exphem.2008.03.014. Epub 2008 May 27.


Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

Pronk CJ, Rossi DJ, Månsson R, Attema JL, Norddahl GL, Chan CK, Sigvardsson M, Weissman IL, Bryder D.

Cell Stem Cell. 2007 Oct 11;1(4):428-42. doi: 10.1016/j.stem.2007.07.005.


Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor.

Chang WC, Ng JK, Nguyen T, Pellissier L, Claeysen S, Hsiao EC, Conklin BR.

PLoS One. 2007 Dec 19;2(12):e1317. doi: 10.1371/journal.pone.0001317.


Hematopoiesis: an evolving paradigm for stem cell biology.

Orkin SH, Zon LI.

Cell. 2008 Feb 22;132(4):631-44. doi: 10.1016/j.cell.2008.01.025.

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