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Results: 1 to 20 of 65

1.

Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease.

Theken KN, Schuck RN, Edin ML, Tran B, Ellis K, Bass A, Lih FB, Tomer KB, Poloyac SM, Wu MC, Hinderliter AL, Zeldin DC, Stouffer GA, Lee CR.

Atherosclerosis. 2012 Jun;222(2):530-6. doi: 10.1016/j.atherosclerosis.2012.03.022. Epub 2012 Mar 27.

PMID:
22503544
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo.

Zhang D, Xie X, Chen Y, Hammock BD, Kong W, Zhu Y.

Circ Res. 2012 Mar 16;110(6):808-17. doi: 10.1161/CIRCRESAHA.111.259325. Epub 2012 Feb 21.

PMID:
22354938
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

NF-κB, the first quarter-century: remarkable progress and outstanding questions.

Hayden MS, Ghosh S.

Genes Dev. 2012 Feb 1;26(3):203-34. doi: 10.1101/gad.183434.111. Review.

PMID:
22302935
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Epoxides and soluble epoxide hydrolase in cardiovascular physiology.

Imig JD.

Physiol Rev. 2012 Jan;92(1):101-30. doi: 10.1152/physrev.00021.2011. Review.

PMID:
22298653
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Delivery of AAV2-CYP2J2 protects remnant kidney in the 5/6-nephrectomized rat via inhibition of apoptosis and fibrosis.

Zhao G, Tu L, Li X, Yang S, Chen C, Xu X, Wang P, Wang DW.

Hum Gene Ther. 2012 Jul;23(7):688-99. doi: 10.1089/hum.2011.135. Epub 2012 Mar 29.

PMID:
22260463
[PubMed - indexed for MEDLINE]
6.

Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis.

Leonarduzzi G, Gamba P, Gargiulo S, Biasi F, Poli G.

Free Radic Biol Med. 2012 Jan 1;52(1):19-34. doi: 10.1016/j.freeradbiomed.2011.09.031. Epub 2011 Oct 2. Review.

PMID:
22037514
[PubMed - indexed for MEDLINE]
7.

Endogenous epoxygenases are modulators of monocyte/macrophage activity.

Bystrom J, Wray JA, Sugden MC, Holness MJ, Swales KE, Warner TD, Edin ML, Zeldin DC, Gilroy DW, Bishop-Bailey D.

PLoS One. 2011;6(10):e26591. doi: 10.1371/journal.pone.0026591. Epub 2011 Oct 19.

PMID:
22028915
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Orphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology.

Guengerich FP, Cheng Q.

Pharmacol Rev. 2011 Sep;63(3):684-99. doi: 10.1124/pr.110.003525. Epub 2011 Jul 7. Review.

PMID:
21737533
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET).

Mitra R, Guo Z, Milani M, Mesaros C, Rodriguez M, Nguyen J, Luo X, Clarke D, Lamba J, Schuetz E, Donner DB, Puli N, Falck JR, Capdevila J, Gupta K, Blair IA, Potter DA.

J Biol Chem. 2011 May 20;286(20):17543-59. doi: 10.1074/jbc.M110.198515. Epub 2011 Mar 14.

PMID:
21402692
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

TRPV channels and vascular function.

Baylie RL, Brayden JE.

Acta Physiol (Oxf). 2011 Sep;203(1):99-116. doi: 10.1111/j.1748-1716.2010.02217.x. Epub 2010 Dec 9. Review.

PMID:
21062421
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice.

Deng Y, Edin ML, Theken KN, Schuck RN, Flake GP, Kannon MA, DeGraff LM, Lih FB, Foley J, Bradbury JA, Graves JP, Tomer KB, Falck JR, Zeldin DC, Lee CR.

FASEB J. 2011 Feb;25(2):703-13. doi: 10.1096/fj.10-171488. Epub 2010 Nov 8.

PMID:
21059750
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.

Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow AL, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, Falck JR, Tomer KB, Zeldin DC.

FASEB J. 2010 Oct;24(10):3770-81. doi: 10.1096/fj.10-160119. Epub 2010 May 21.

PMID:
20495177
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Leucocyte/endothelium interactions and microvessel permeability: coupled or uncoupled?

He P.

Cardiovasc Res. 2010 Jul 15;87(2):281-90. doi: 10.1093/cvr/cvq140. Epub 2010 May 13. Review.

PMID:
20472564
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.

Luo P, Chang HH, Zhou Y, Zhang S, Hwang SH, Morisseau C, Wang CY, Inscho EW, Hammock BD, Wang MH.

J Pharmacol Exp Ther. 2010 Aug;334(2):430-8. doi: 10.1124/jpet.110.167544. Epub 2010 May 3.

PMID:
20439437
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice.

Revermann M, Schloss M, Barbosa-Sicard E, Mieth A, Liebner S, Morisseau C, Geisslinger G, Schermuly RT, Fleming I, Hammock BD, Brandes RP.

Arterioscler Thromb Vasc Biol. 2010 May;30(5):909-14. doi: 10.1161/ATVBAHA.110.204099. Epub 2010 Mar 11.

PMID:
20224052
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Molecular regulators of leucocyte chemotaxis during inflammation.

Wong CH, Heit B, Kubes P.

Cardiovasc Res. 2010 May 1;86(2):183-91. doi: 10.1093/cvr/cvq040. Epub 2010 Feb 2. Review.

PMID:
20124403
[PubMed - indexed for MEDLINE]
Free Article
17.

The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo.

Wray JA, Sugden MC, Zeldin DC, Greenwood GK, Samsuddin S, Miller-Degraff L, Bradbury JA, Holness MJ, Warner TD, Bishop-Bailey D.

PLoS One. 2009 Oct 12;4(10):e7421. doi: 10.1371/journal.pone.0007421.

PMID:
19823578
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Inhibition of soluble epoxide hydrolase attenuated atherosclerosis, abdominal aortic aneurysm formation, and dyslipidemia.

Zhang LN, Vincelette J, Cheng Y, Mehra U, Chen D, Anandan SK, Gless R, Webb HK, Wang YX.

Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1265-70. doi: 10.1161/ATVBAHA.109.186064. Epub 2009 Aug 10.

PMID:
19667112
[PubMed - indexed for MEDLINE]
Free Article
19.

Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology.

Buczynski MW, Dumlao DS, Dennis EA.

J Lipid Res. 2009 Jun;50(6):1015-38. doi: 10.1194/jlr.R900004-JLR200. Epub 2009 Feb 24. Review. Erratum in: J Lipid Res. 2009 Jul;50(7):1505.

PMID:
19244215
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Relaxing effects of 17(18)-EpETE on arterial and airway smooth muscles in human lung.

Morin C, Sirois M, Echave V, Rizcallah E, Rousseau E.

Am J Physiol Lung Cell Mol Physiol. 2009 Jan;296(1):L130-9. doi: 10.1152/ajplung.90436.2008. Epub 2008 Oct 31.

PMID:
18978038
[PubMed - indexed for MEDLINE]
Free Article

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