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Results: 1 to 20 of 28

1.

Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease.

Ingelsson E, Yin L, Bäck M.

J Allergy Clin Immunol. 2012 Mar;129(3):702-707.e2. doi: 10.1016/j.jaci.2011.11.052. Epub 2012 Jan 12.

PMID:
22244598
[PubMed - indexed for MEDLINE]
2.

Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease.

Haeggström JZ, Funk CD.

Chem Rev. 2011 Oct 12;111(10):5866-98. doi: 10.1021/cr200246d. Epub 2011 Sep 22. Review. No abstract available.

PMID:
21936577
[PubMed - indexed for MEDLINE]
3.

A selective cysteinyl leukotriene receptor 2 antagonist blocks myocardial ischemia/reperfusion injury and vascular permeability in mice.

Ni NC, Yan D, Ballantyne LL, Barajas-Espinosa A, St Amand T, Pratt DA, Funk CD.

J Pharmacol Exp Ther. 2011 Dec;339(3):768-78. doi: 10.1124/jpet.111.186031. Epub 2011 Sep 8.

PMID:
21903747
[PubMed - indexed for MEDLINE]
Free Article
4.

Leukotriene B4 receptor-1 mediates intermittent hypoxia-induced atherogenesis.

Li RC, Haribabu B, Mathis SP, Kim J, Gozal D.

Am J Respir Crit Care Med. 2011 Jul 1;184(1):124-31. doi: 10.1164/rccm.201012-2039OC. Epub 2011 Apr 14.

PMID:
21493735
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Inhibition of leukotriene C4 action reduces oxidative stress and apoptosis in cardiomyocytes and impedes remodeling after myocardial injury.

Becher UM, Ghanem A, Tiyerili V, Fürst DO, Nickenig G, Mueller CF.

J Mol Cell Cardiol. 2011 Mar;50(3):570-7. doi: 10.1016/j.yjmcc.2010.11.013. Epub 2010 Nov 26.

PMID:
21112334
[PubMed - indexed for MEDLINE]
6.

Advances in eicosanoid research, novel therapeutic implications.

Haeggström JZ, Rinaldo-Matthis A, Wheelock CE, Wetterholm A.

Biochem Biophys Res Commun. 2010 May 21;396(1):135-9. doi: 10.1016/j.bbrc.2010.03.140. Review.

PMID:
20494126
[PubMed - indexed for MEDLINE]
7.

The 5-lipoxygenase/leukotriene pathway in preclinical models of cardiovascular disease.

Poeckel D, Funk CD.

Cardiovasc Res. 2010 May 1;86(2):243-53. doi: 10.1093/cvr/cvq016. Epub 2010 Jan 21. Review.

PMID:
20093252
[PubMed - indexed for MEDLINE]
Free Article
8.

Increased urinary leukotriene E4 excretion in obstructive sleep apnea: effects of obesity and hypoxia.

Stanke-Labesque F, Bäck M, Lefebvre B, Tamisier R, Baguet JP, Arnol N, Lévy P, Pépin JL.

J Allergy Clin Immunol. 2009 Aug;124(2):364-70, 370.e1-2. doi: 10.1016/j.jaci.2009.05.033. Epub 2009 Jul 12.

PMID:
19596146
[PubMed - indexed for MEDLINE]
9.

GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.

Maekawa A, Balestrieri B, Austen KF, Kanaoka Y.

Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11685-90. doi: 10.1073/pnas.0905364106. Epub 2009 Jun 26.

PMID:
19561298
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors.

Maekawa A, Kanaoka Y, Xing W, Austen KF.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16695-700. doi: 10.1073/pnas.0808993105. Epub 2008 Oct 17.

PMID:
18931305
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genetic and pharmacological inhibition of the 5-lipoxygenase/leukotriene pathway in atherosclerotic lesion development in ApoE deficient mice.

Cao RY, St Amand T, Gräbner R, Habenicht AJ, Funk CD.

Atherosclerosis. 2009 Apr;203(2):395-400. doi: 10.1016/j.atherosclerosis.2008.07.045. Epub 2008 Aug 15.

PMID:
18804760
[PubMed - indexed for MEDLINE]
12.

Endothelial cysteinyl leukotriene 2 receptor expression mediates myocardial ischemia-reperfusion injury.

Jiang W, Hall SR, Moos MP, Cao RY, Ishii S, Ogunyankin KO, Melo LG, Funk CD.

Am J Pathol. 2008 Mar;172(3):592-602. doi: 10.2353/ajpath.2008.070834. Epub 2008 Feb 14.

PMID:
18276782
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Atherosclerosis: the path from genomics to therapeutics.

Miller DT, Ridker PM, Libby P, Kwiatkowski DJ.

J Am Coll Cardiol. 2007 Apr 17;49(15):1589-99. Epub 2007 Apr 2. Review.

PMID:
17433948
[PubMed - indexed for MEDLINE]
Free Article
14.

Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.

Qiu H, Gabrielsen A, Agardh HE, Wan M, Wetterholm A, Wong CH, Hedin U, Swedenborg J, Hansson GK, Samuelsson B, Paulsson-Berne G, Haeggström JZ.

Proc Natl Acad Sci U S A. 2006 May 23;103(21):8161-6. Epub 2006 May 12.

PMID:
16698924
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction.

Helgadottir A, Manolescu A, Helgason A, Thorleifsson G, Thorsteinsdottir U, Gudbjartsson DF, Gretarsdottir S, Magnusson KP, Gudmundsson G, Hicks A, Jonsson T, Grant SF, Sainz J, O'Brien SJ, Sveinbjornsdottir S, Valdimarsson EM, Matthiasson SE, Levey AI, Abramson JL, Reilly MP, Vaccarino V, Wolfe ML, Gudnason V, Quyyumi AA, Topol EJ, Rader DJ, Thorgeirsson G, Gulcher JR, Hakonarson H, Kong A, Stefansson K.

Nat Genet. 2006 Jan;38(1):68-74. Epub 2005 Nov 10.

PMID:
16282974
[PubMed - indexed for MEDLINE]
16.

Leukotriene modifiers as potential therapeutics for cardiovascular disease.

Funk CD.

Nat Rev Drug Discov. 2005 Aug;4(8):664-72. Review.

PMID:
16041318
[PubMed - indexed for MEDLINE]
17.

Cardiovascular functional phenotypes and pharmacological responses in apolipoprotein E deficient mice.

Wang YX.

Neurobiol Aging. 2005 Mar;26(3):309-16. Review.

PMID:
15639308
[PubMed - indexed for MEDLINE]
18.

The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke.

Helgadottir A, Manolescu A, Thorleifsson G, Gretarsdottir S, Jonsdottir H, Thorsteinsdottir U, Samani NJ, Gudmundsson G, Grant SF, Thorgeirsson G, Sveinbjornsdottir S, Valdimarsson EM, Matthiasson SE, Johannsson H, Gudmundsdottir O, Gurney ME, Sainz J, Thorhallsdottir M, Andresdottir M, Frigge ML, Topol EJ, Kong A, Gudnason V, Hakonarson H, Gulcher JR, Stefansson K.

Nat Genet. 2004 Mar;36(3):233-9. Epub 2004 Feb 8.

PMID:
14770184
[PubMed - indexed for MEDLINE]
19.

Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis.

Dwyer JH, Allayee H, Dwyer KM, Fan J, Wu H, Mar R, Lusis AJ, Mehrabian M.

N Engl J Med. 2004 Jan 1;350(1):29-37.

PMID:
14702425
[PubMed - indexed for MEDLINE]
Free Article
20.

Enzymes and receptors in the leukotriene cascade.

Haeggström JZ, Wetterholm A.

Cell Mol Life Sci. 2002 May;59(5):742-53. Review.

PMID:
12088275
[PubMed - indexed for MEDLINE]

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