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Results: 1 to 20 of 45

1.

BioMart: driving a paradigm change in biological data management.

Kasprzyk A.

Database (Oxford). 2011 Nov 13;2011:bar049. doi: 10.1093/database/bar049. Print 2011. No abstract available.

PMID:
22083790
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Downregulation of Filamin A interacting protein 1-like is associated with promoter methylation and induces an invasive phenotype in ovarian cancer.

Burton ER, Gaffar A, Lee SJ, Adeshuko F, Whitney KD, Chung JY, Hewitt SM, Huang GS, Goldberg GL, Libutti SK, Kwon M.

Mol Cancer Res. 2011 Aug;9(8):1126-38. doi: 10.1158/1541-7786.MCR-11-0162. Epub 2011 Jun 21.

PMID:
21693594
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The selective class I PI3K inhibitor CH5132799 targets human cancers harboring oncogenic PIK3CA mutations.

Tanaka H, Yoshida M, Tanimura H, Fujii T, Sakata K, Tachibana Y, Ohwada J, Ebiike H, Kuramoto S, Morita K, Yoshimura Y, Yamazaki T, Ishii N, Kondoh O, Aoki Y.

Clin Cancer Res. 2011 May 15;17(10):3272-81. doi: 10.1158/1078-0432.CCR-10-2882. Epub 2011 May 10.

PMID:
21558396
[PubMed - indexed for MEDLINE]
Free Article
4.

The genomic complexity of primary human prostate cancer.

Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, Sivachenko AY, Sboner A, Esgueva R, Pflueger D, Sougnez C, Onofrio R, Carter SL, Park K, Habegger L, Ambrogio L, Fennell T, Parkin M, Saksena G, Voet D, Ramos AH, Pugh TJ, Wilkinson J, Fisher S, Winckler W, Mahan S, Ardlie K, Baldwin J, Simons JW, Kitabayashi N, MacDonald TY, Kantoff PW, Chin L, Gabriel SB, Gerstein MB, Golub TR, Meyerson M, Tewari A, Lander ES, Getz G, Rubin MA, Garraway LA.

Nature. 2011 Feb 10;470(7333):214-20. doi: 10.1038/nature09744.

PMID:
21307934
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The genetic landscape of the childhood cancer medulloblastoma.

Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.

Science. 2011 Jan 28;331(6016):435-9. doi: 10.1126/science.1198056. Epub 2010 Dec 16.

PMID:
21163964
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

DMDM: domain mapping of disease mutations.

Peterson TA, Adadey A, Santana-Cruz I, Sun Y, Winder A, Kann MG.

Bioinformatics. 2010 Oct 1;26(19):2458-9. doi: 10.1093/bioinformatics/btq447. Epub 2010 Aug 4.

PMID:
20685956
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data.

Wang K, Li M, Hakonarson H.

Nucleic Acids Res. 2010 Sep;38(16):e164. doi: 10.1093/nar/gkq603. Epub 2010 Jul 3.

PMID:
20601685
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inferring the functional effects of mutation through clusters of mutations in homologous proteins.

Yue P, Forrest WF, Kaminker JS, Lohr S, Zhang Z, Cavet G.

Hum Mutat. 2010 Mar;31(3):264-71. doi: 10.1002/humu.21194.

PMID:
20052764
[PubMed - indexed for MEDLINE]
9.

Folding of tetrameric p53: oligomerization and tumorigenic mutations induce misfolding and loss of function.

Lubin DJ, Butler JS, Loh SN.

J Mol Biol. 2010 Jan 29;395(4):705-16. doi: 10.1016/j.jmb.2009.11.013. Epub 2009 Nov 11.

PMID:
19913028
[PubMed - indexed for MEDLINE]
10.

Edgetic perturbation models of human inherited disorders.

Zhong Q, Simonis N, Li QR, Charloteaux B, Heuze F, Klitgord N, Tam S, Yu H, Venkatesan K, Mou D, Swearingen V, Yildirim MA, Yan H, Dricot A, Szeto D, Lin C, Hao T, Fan C, Milstein S, Dupuy D, Brasseur R, Hill DE, Cusick ME, Vidal M.

Mol Syst Biol. 2009;5:321. doi: 10.1038/msb.2009.80. Epub 2009 Nov 3.

PMID:
19888216
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Sequence and structure signatures of cancer mutation hotspots in protein kinases.

Dixit A, Yi L, Gowthaman R, Torkamani A, Schork NJ, Verkhivker GM.

PLoS One. 2009 Oct 16;4(10):e7485. doi: 10.1371/journal.pone.0007485.

PMID:
19834613
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Somatic mutations affect key pathways in lung adenocarcinoma.

Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, Larson DE, Chen K, Dooling DJ, Sabo A, Hawes AC, Shen H, Jhangiani SN, Lewis LR, Hall O, Zhu Y, Mathew T, Ren Y, Yao J, Scherer SE, Clerc K, Metcalf GA, Ng B, Milosavljevic A, Gonzalez-Garay ML, Osborne JR, Meyer R, Shi X, Tang Y, Koboldt DC, Lin L, Abbott R, Miner TL, Pohl C, Fewell G, Haipek C, Schmidt H, Dunford-Shore BH, Kraja A, Crosby SD, Sawyer CS, Vickery T, Sander S, Robinson J, Winckler W, Baldwin J, Chirieac LR, Dutt A, Fennell T, Hanna M, Johnson BE, Onofrio RC, Thomas RK, Tonon G, Weir BA, Zhao X, Ziaugra L, Zody MC, Giordano T, Orringer MB, Roth JA, Spitz MR, Wistuba II, Ozenberger B, Good PJ, Chang AC, Beer DG, Watson MA, Ladanyi M, Broderick S, Yoshizawa A, Travis WD, Pao W, Province MA, Weinstock GM, Varmus HE, Gabriel SB, Lander ES, Gibbs RA, Meyerson M, Wilson RK.

Nature. 2008 Oct 23;455(7216):1069-75. doi: 10.1038/nature07423.

PMID:
18948947
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

InterPro: the integrative protein signature database.

Hunter S, Apweiler R, Attwood TK, Bairoch A, Bateman A, Binns D, Bork P, Das U, Daugherty L, Duquenne L, Finn RD, Gough J, Haft D, Hulo N, Kahn D, Kelly E, Laugraud A, Letunic I, Lonsdale D, Lopez R, Madera M, Maslen J, McAnulla C, McDowall J, Mistry J, Mitchell A, Mulder N, Natale D, Orengo C, Quinn AF, Selengut JD, Sigrist CJ, Thimma M, Thomas PD, Valentin F, Wilson D, Wu CH, Yeats C.

Nucleic Acids Res. 2009 Jan;37(Database issue):D211-5. doi: 10.1093/nar/gkn785. Epub 2008 Oct 21.

PMID:
18940856
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Functional characterization of filamin a interacting protein 1-like, a novel candidate for antivascular cancer therapy.

Kwon M, Hanna E, Lorang D, He M, Quick JS, Adem A, Stevenson C, Chung JY, Hewitt SM, Zudaire E, Esposito D, Cuttitta F, Libutti SK.

Cancer Res. 2008 Sep 15;68(18):7332-41. doi: 10.1158/0008-5472.CAN-08-1087.

PMID:
18794120
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.

Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Jimeno A, Hong SM, Fu B, Lin MT, Calhoun ES, Kamiyama M, Walter K, Nikolskaya T, Nikolsky Y, Hartigan J, Smith DR, Hidalgo M, Leach SD, Klein AP, Jaffee EM, Goggins M, Maitra A, Iacobuzio-Donahue C, Eshleman JR, Kern SE, Hruban RH, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW.

Science. 2008 Sep 26;321(5897):1801-6. doi: 10.1126/science.1164368. Epub 2008 Sep 4.

PMID:
18772397
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile.

Ducray F, Idbaih A, de Reyniès A, Bièche I, Thillet J, Mokhtari K, Lair S, Marie Y, Paris S, Vidaud M, Hoang-Xuan K, Delattre O, Delattre JY, Sanson M.

Mol Cancer. 2008 May 20;7:41. doi: 10.1186/1476-4598-7-41.

PMID:
18492260
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Functional classification analysis of somatically mutated genes in human breast and colorectal cancers.

Chittenden TW, Howe EA, Culhane AC, Sultana R, Taylor JM, Holmes C, Quackenbush J.

Genomics. 2008 Jun;91(6):508-11. doi: 10.1016/j.ygeno.2008.03.002. Epub 2008 Apr 22.

PMID:
18434084
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The Pfam protein families database.

Finn RD, Tate J, Mistry J, Coggill PC, Sammut SJ, Hotz HR, Ceric G, Forslund K, Eddy SR, Sonnhammer EL, Bateman A.

Nucleic Acids Res. 2008 Jan;36(Database issue):D281-8. Epub 2007 Nov 26.

PMID:
18039703
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The genomic landscapes of human breast and colorectal cancers.

Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, Nikolsky Y, Karchin R, Wilson PA, Kaminker JS, Zhang Z, Croshaw R, Willis J, Dawson D, Shipitsin M, Willson JK, Sukumar S, Polyak K, Park BH, Pethiyagoda CL, Pant PV, Ballinger DG, Sparks AB, Hartigan J, Smith DR, Suh E, Papadopoulos N, Buckhaults P, Markowitz SD, Parmigiani G, Kinzler KW, Velculescu VE, Vogelstein B.

Science. 2007 Nov 16;318(5853):1108-13. Epub 2007 Oct 11.

PMID:
17932254
[PubMed - indexed for MEDLINE]
Free Article
20.

Comment on "The consensus coding sequences of human breast and colorectal cancers".

Rubin AF, Green P.

Science. 2007 Sep 14;317(5844):1500.

PMID:
17872429
[PubMed - indexed for MEDLINE]
Free Article
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