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Antigen-independent IFN-γ production by human naïve CD4 T cells activated by IL-12 plus IL-18.

Munk RB, Sugiyama K, Ghosh P, Sasaki CY, Rezanka L, Banerjee K, Takahashi H, Sen R, Longo DL.

PLoS One. 2011 May 10;6(5):e18553. doi: 10.1371/journal.pone.0018553.


Decreasing prevalence of herpes simplex virus-2 antibodies in selected groups of women in Sweden.

Berntsson M, Tunbäck P, Ellström A, Krantz I, Löwhagen GB.

Acta Derm Venereol. 2009 Nov;89(6):623-6. doi: 10.2340/00015555-0699.


Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells.

Placek K, Gasparian S, Coffre M, Maiella S, Sechet E, Bianchi E, Rogge L.

J Immunol. 2009 Dec 15;183(12):7743-51. doi: 10.4049/jimmunol.0803812. Epub .


Mannose-binding lectin 2 gene polymorphism in recurrent herpes simplex virus 2 infection.

Seppänen M, Lokki ML, Lappalainen M, Hiltunen-Back E, Rovio AT, Kares S, Hurme M, Aittoniemi J.

Hum Immunol. 2009 Apr;70(4):218-21. doi: 10.1016/j.humimm.2009.01.022. Epub 2009 Feb 4.


Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.

Schulz EG, Mariani L, Radbruch A, Höfer T.

Immunity. 2009 May;30(5):673-83. doi: 10.1016/j.immuni.2009.03.013. Epub 2009 Apr 30.


A 3'-untranslated region polymorphism in the TBX21 gene encoding T-bet is a risk factor for genital herpes simplex virus type 2 infection in humans.

Svensson A, Bergin AM, Löwhagen GB, Tunbäck P, Bellner L, Padyukov L, Eriksson K.

J Gen Virol. 2008 Sep;89(Pt 9):2262-8. doi: 10.1099/vir.0.2008/001305-0.


STAT4: genetics, mechanisms, and implications for autoimmunity.

Korman BD, Kastner DL, Gregersen PK, Remmers EF.

Curr Allergy Asthma Rep. 2008 Sep;8(5):398-403. Review.


A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.

Sigurdsson S, Nordmark G, Garnier S, Grundberg E, Kwan T, Nilsson O, Eloranta ML, Gunnarsson I, Svenungsson E, Sturfelt G, Bengtsson AA, Jönsen A, Truedsson L, Rantapää-Dahlqvist S, Eriksson C, Alm G, Göring HH, Pastinen T, Syvänen AC, Rönnblom L.

Hum Mol Genet. 2008 Sep 15;17(18):2868-76. doi: 10.1093/hmg/ddn184. Epub 2008 Jun 25.


Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.

Taylor KE, Remmers EF, Lee AT, Ortmann WA, Plenge RM, Tian C, Chung SA, Nititham J, Hom G, Kao AH, Demirci FY, Kamboh MI, Petri M, Manzi S, Kastner DL, Seldin MF, Gregersen PK, Behrens TW, Criswell LA.

PLoS Genet. 2008 May 30;4(5):e1000084. doi: 10.1371/journal.pgen.1000084.


Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and allergic airway inflammation.

Furuta S, Kagami S, Tamachi T, Ikeda K, Fujiwara M, Suto A, Hirose K, Watanabe N, Saito Y, Iwamoto I, Nakajima H.

J Immunol. 2008 May 15;180(10):6656-62.


Polymorphisms in TLR2 are associated with increased viral shedding and lesional rate in patients with genital herpes simplex virus Type 2 infection.

Bochud PY, Magaret AS, Koelle DM, Aderem A, Wald A.

J Infect Dis. 2007 Aug 15;196(4):505-9. Epub 2007 Jun 29.


STAT4: a critical regulator of inflammation in vivo.

Kaplan MH.

Immunol Res. 2005;31(3):231-42. Review.


Protective immunity to genital herpes simplex [correction of simpex] virus type 2 infection is mediated by T-bet.

Svensson A, Nordström I, Sun JB, Eriksson K.

J Immunol. 2005 May 15;174(10):6266-73.


Mannan-binding lectin modulates the response to HSV-2 infection.

Gadjeva M, Paludan SR, Thiel S, Slavov V, Ruseva M, Eriksson K, Löwhagen GB, Shi L, Takahashi K, Ezekowitz A, Jensenius JC.

Clin Exp Immunol. 2004 Nov;138(2):304-11.


CD4(+) T-cell responses to herpes simplex virus type 2 (HSV-2) glycoprotein G are type specific and differ in symptomatic and asymptomatic HSV-2-infected individuals.

Eriksson K, Bellner L, Görander S, Löwhagen GB, Tunbäck P, Rydberg K, Liljeqvist JA.

J Gen Virol. 2004 Aug;85(Pt 8):2139-47.


Epidemiology of herpes simplex virus type 2 infection in the developing world.

Weiss H.

Herpes. 2004 Apr;11 Suppl 1:24A-35A. Review.


Prevalence of herpes simplex virus antibodies in childhood and adolescence: a cross-sectional study.

Tunbäck P, Bergström T, Andersson AS, Nordin P, Krantz I, Löwhagen GB.

Scand J Infect Dis. 2003;35(8):498-502.

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