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What is the value of hypothermia in acute neurologic diseases and status epilepticus?

Rossetti AO.

Epilepsia. 2011 Oct;52 Suppl 8:64-6. doi: 10.1111/j.1528-1167.2011.03241.x. Review.


The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus, and PTH.

Liu J, Lv F, Sun W, Tao C, Ding G, Karaplis A, Brown E, Goltzman D, Miao D.

PLoS Genet. 2011 Sep;7(9):e1002294. doi: 10.1371/journal.pgen.1002294. Epub 2011 Sep 22.


Early-life seizures produce lasting alterations in the structure and function of the prefrontal cortex.

Kleen JK, Sesqué A, Wu EX, Miller FA, Hernan AE, Holmes GL, Scott RC.

Epilepsy Behav. 2011 Oct;22(2):214-9. doi: 10.1016/j.yebeh.2011.07.022. Epub 2011 Aug 27.


Hypothermia is correlated with seizure absence in perinatal stroke.

Harbert MJ, Tam EW, Glass HC, Bonifacio SL, Haeusslein LA, Barkovich AJ, Jeremy RJ, Rogers EE, Glidden DV, Ferriero DM.

J Child Neurol. 2011 Sep;26(9):1126-30. doi: 10.1177/0883073811408092. Epub 2011 Jun 23.


Topiramate for the treatment of neonatal seizures.

Glass HC, Poulin C, Shevell MI.

Pediatr Neurol. 2011 Jun;44(6):439-42. doi: 10.1016/j.pediatrneurol.2011.01.006.


Electrographic seizures during therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy.

Wusthoff CJ, Dlugos DJ, Gutierrez-Colina A, Wang A, Cook N, Donnelly M, Clancy R, Abend NS.

J Child Neurol. 2011 Jun;26(6):724-8. doi: 10.1177/0883073810390036. Epub 2011 Mar 29.


Development of later life spontaneous seizures in a rodent model of hypoxia-induced neonatal seizures.

Rakhade SN, Klein PM, Huynh T, Hilario-Gomez C, Kosaras B, Rotenberg A, Jensen FE.

Epilepsia. 2011 Apr;52(4):753-65. doi: 10.1111/j.1528-1167.2011.02992.x. Epub 2011 Mar 2.


Levetiracetam for treatment of neonatal seizures.

Abend NS, Gutierrez-Colina AM, Monk HM, Dlugos DJ, Clancy RR.

J Child Neurol. 2011 Apr;26(4):465-70. doi: 10.1177/0883073810384263. Epub 2011 Jan 13.


State of the controlled clinical trial enterprise in the United States.

Krall RL.

Clin Pharmacol Ther. 2011 Feb;89(2):225-8. doi: 10.1038/clpt.2010.292. Epub 2010 Dec 29.


Using amplitude-integrated EEG in neonatal intensive care.

Tao JD, Mathur AM.

J Perinatol. 2010 Oct;30 Suppl:S73-81. doi: 10.1038/jp.2010.93. Review.


A novel preclinical rodent model of collagenase-induced germinal matrix/intraventricular hemorrhage.

Alles YC, Greggio S, Alles RM, Azevedo PN, Xavier LL, DaCosta JC.

Brain Res. 2010 Oct 14;1356:130-8. doi: 10.1016/j.brainres.2010.07.106. Epub 2010 Aug 6.


Recurrent neonatal seizures result in long-term increases in neuronal network excitability in the rat neocortex.

Isaeva E, Isaev D, Savrasova A, Khazipov R, Holmes GL.

Eur J Neurosci. 2010 Apr;31(8):1446-55. doi: 10.1111/j.1460-9568.2010.07179.x. Epub 2010 Apr 6.


Trends in risks associated with new drug development: success rates for investigational drugs.

DiMasi JA, Feldman L, Seckler A, Wilson A.

Clin Pharmacol Ther. 2010 Mar;87(3):272-7. doi: 10.1038/clpt.2009.295. Epub 2010 Feb 3. Review.


Effect of treatment of subclinical neonatal seizures detected with aEEG: randomized, controlled trial.

van Rooij LG, Toet MC, van Huffelen AC, Groenendaal F, Laan W, Zecic A, de Haan T, van Straaten IL, Vrancken S, van Wezel G, van der Sluijs J, Ter Horst H, Gavilanes D, Laroche S, Naulaers G, de Vries LS.

Pediatrics. 2010 Feb;125(2):e358-66. doi: 10.1542/peds.2009-0136. Epub 2010 Jan 25.


Seizures are associated with brain injury severity in a neonatal model of hypoxia-ischemia.

Björkman ST, Miller SM, Rose SE, Burke C, Colditz PB.

Neuroscience. 2010 Mar 10;166(1):157-67. doi: 10.1016/j.neuroscience.2009.11.067. Epub 2009 Dec 16.


A model of symptomatic infantile spasms syndrome.

Scantlebury MH, Galanopoulou AS, Chudomelova L, Raffo E, Betancourth D, Moshé SL.

Neurobiol Dis. 2010 Mar;37(3):604-12. doi: 10.1016/j.nbd.2009.11.011. Epub 2009 Nov 26.


Long-term suppression of GABAergic activity by neonatal seizures in rat somatosensory cortex.

Isaeva E, Isaev D, Khazipov R, Holmes GL.

Epilepsy Res. 2009 Dec;87(2-3):286-9. doi: 10.1016/j.eplepsyres.2009.09.011. Epub 2009 Oct 13.


Focal brain malformations: seizures, signaling, sequencing.

Crino PB.

Epilepsia. 2009 Oct;50 Suppl 9:3-8. doi: 10.1111/j.1528-1167.2009.02289.x.


A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment.

Price MG, Yoo JW, Burgess DL, Deng F, Hrachovy RA, Frost JD Jr, Noebels JL.

J Neurosci. 2009 Jul 8;29(27):8752-63. doi: 10.1523/JNEUROSCI.0915-09.2009.

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