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Results: 1 to 20 of 41

References for PMC Articles for PubMed (Select 22684507)


Tapping natural reservoirs of homing endonucleases for targeted gene modification.

Takeuchi R, Lambert AR, Mak AN, Jacoby K, Dickson RJ, Gloor GB, Scharenberg AM, Edgell DR, Stoddard BL.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13077-82. doi: 10.1073/pnas.1107719108. Epub 2011 Jul 22.


Tracking genome engineering outcome at individual DNA breakpoints.

Certo MT, Ryu BY, Annis JE, Garibov M, Jarjour J, Rawlings DJ, Scharenberg AM.

Nat Methods. 2011 Jul 10;8(8):671-6. doi: 10.1038/nmeth.1648.


Gene therapy for primary immunodeficiencies: looking ahead, toward gene correction.

Pessach IM, Notarangelo LD.

J Allergy Clin Immunol. 2011 Jun;127(6):1344-50. doi: 10.1016/j.jaci.2011.02.027. Epub 2011 Mar 25. Review.


De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks.

Mahfouz MM, Li L, Shamimuzzaman M, Wibowo A, Fang X, Zhu JK.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2623-8. doi: 10.1073/pnas.1019533108. Epub 2011 Jan 24.


ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules.

Leaver-Fay A, Tyka M, Lewis SM, Lange OF, Thompson J, Jacak R, Kaufman K, Renfrew PD, Smith CA, Sheffler W, Davis IW, Cooper S, Treuille A, Mandell DJ, Richter F, Ban YE, Fleishman SJ, Corn JE, Kim DE, Lyskov S, Berrondo M, Mentzer S, Popović Z, Havranek JJ, Karanicolas J, Das R, Meiler J, Kortemme T, Gray JJ, Kuhlman B, Baker D, Bradley P.

Methods Enzymol. 2011;487:545-74. doi: 10.1016/B978-0-12-381270-4.00019-6.


Targeted genome editing in pluripotent stem cells using zinc-finger nucleases.

Bobis-Wozowicz S, Osiak A, Rahman SH, Cathomen T.

Methods. 2011 Apr;53(4):339-46. doi: 10.1016/j.ymeth.2010.12.019. Epub 2010 Dec 23.


A TALE nuclease architecture for efficient genome editing.

Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ.

Nat Biotechnol. 2011 Feb;29(2):143-8. doi: 10.1038/nbt.1755. Epub 2010 Dec 22.


Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders.

Sather BD, Ryu BY, Stirling BV, Garibov M, Kerns HM, Humblet-Baron S, Astrakhan A, Rawlings DJ.

Mol Ther. 2011 Mar;19(3):515-25. doi: 10.1038/mt.2010.259. Epub 2010 Dec 7.


The DNA damage response: making it safe to play with knives.

Ciccia A, Elledge SJ.

Mol Cell. 2010 Oct 22;40(2):179-204. doi: 10.1016/j.molcel.2010.09.019. Review.


Genome editing with engineered zinc finger nucleases.

Urnov FD, Rebar EJ, Holmes MC, Zhang HS, Gregory PD.

Nat Rev Genet. 2010 Sep;11(9):636-46. doi: 10.1038/nrg2842. Review.


Regulation of homologous recombination in eukaryotes.

Heyer WD, Ehmsen KT, Liu J.

Annu Rev Genet. 2010;44:113-39. doi: 10.1146/annurev-genet-051710-150955. Review.


Using zinc finger nucleases for efficient and heritable gene disruption in zebrafish.

McCammon JM, Amacher SL.

Methods Mol Biol. 2010;649:281-98. doi: 10.1007/978-1-60761-753-2_18.


Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs.

Ashworth J, Taylor GK, Havranek JJ, Quadri SA, Stoddard BL, Baker D.

Nucleic Acids Res. 2010 Sep;38(16):5601-8. doi: 10.1093/nar/gkq283. Epub 2010 Apr 30.


Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffolds.

Grizot S, Epinat JC, Thomas S, Duclert A, Rolland S, Pâques F, Duchateau P.

Nucleic Acids Res. 2010 Apr;38(6):2006-18. doi: 10.1093/nar/gkp1171. Epub 2009 Dec 21.


High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.

Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM.

Nucleic Acids Res. 2009 Nov;37(20):6871-80. doi: 10.1093/nar/gkp726. Epub 2009 Sep 8.


Targeted manipulation of mammalian genomes using designed zinc finger nucleases.

Kandavelou K, Ramalingam S, London V, Mani M, Wu J, Alexeev V, Civin CI, Chandrasegaran S.

Biochem Biophys Res Commun. 2009 Oct 9;388(1):56-61. doi: 10.1016/j.bbrc.2009.07.112. Epub 2009 Jul 25.


Genes within genes: multiple LAGLIDADG homing endonucleases target the ribosomal protein S3 gene encoded within an rnl group I intron of Ophiostoma and related taxa.

Sethuraman J, Majer A, Friedrich NC, Edgell DR, Hausner G.

Mol Biol Evol. 2009 Oct;26(10):2299-315. doi: 10.1093/molbev/msp145. Epub 2009 Jul 13.


The ubiquitylation machinery of the endoplasmic reticulum.

Hirsch C, Gauss R, Horn SC, Neuber O, Sommer T.

Nature. 2009 Mar 26;458(7237):453-60. doi: 10.1038/nature07962. Review.


Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins.

Li H, Pellenz S, Ulge U, Stoddard BL, Monnat RJ Jr.

Nucleic Acids Res. 2009 Apr;37(5):1650-62. doi: 10.1093/nar/gkp004. Epub 2009 Jan 19.


One step at a time: endoplasmic reticulum-associated degradation.

Vembar SS, Brodsky JL.

Nat Rev Mol Cell Biol. 2008 Dec;9(12):944-57. doi: 10.1038/nrm2546. Epub 2008 Nov 12. Review.

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