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Items: 1 to 20 of 57

1.

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.

Meerang M, Ritz D, Paliwal S, Garajova Z, Bosshard M, Mailand N, Janscak P, Hübscher U, Meyer H, Ramadan K.

Nat Cell Biol. 2011 Oct 23;13(11):1376-82. doi: 10.1038/ncb2367.

PMID:
22020440
2.

SUMO playing tag with ubiquitin.

Praefcke GJ, Hofmann K, Dohmen RJ.

Trends Biochem Sci. 2012 Jan;37(1):23-31. doi: 10.1016/j.tibs.2011.09.002. Epub 2011 Oct 20. Review.

PMID:
22018829
3.

KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.

Goodarzi AA, Kurka T, Jeggo PA.

Nat Struct Mol Biol. 2011 Jun 5;18(7):831-9. doi: 10.1038/nsmb.2077.

PMID:
21642969
4.

SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability.

Heideker J, Prudden J, Perry JJ, Tainer JA, Boddy MN.

PLoS Genet. 2011 Mar;7(3):e1001320. doi: 10.1371/journal.pgen.1001320. Epub 2011 Mar 3.

5.

Purification and identification of endogenous polySUMO conjugates.

Bruderer R, Tatham MH, Plechanovova A, Matic I, Garg AK, Hay RT.

EMBO Rep. 2011 Feb;12(2):142-8. doi: 10.1038/embor.2010.206. Epub 2011 Jan 21.

6.

Cdc48/p97 mediates UV-dependent turnover of RNA Pol II.

Verma R, Oania R, Fang R, Smith GT, Deshaies RJ.

Mol Cell. 2011 Jan 7;41(1):82-92. doi: 10.1016/j.molcel.2010.12.017.

7.

Connecting the Dots: Interplay between Ubiquitylation and SUMOylation at DNA Double-Strand Breaks.

Tang JB, Greenberg RA.

Genes Cancer. 2010 Jul;1(7):787-96. doi: 10.1177/1947601910382774.

8.

Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen.

Hu XV, Rodrigues TM, Tao H, Baker RK, Miraglia L, Orth AP, Lyons GE, Schultz PG, Wu X.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15087-92. doi: 10.1073/pnas.1009025107. Epub 2010 Aug 9.

9.

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks.

Shanbhag NM, Rafalska-Metcalf IU, Balane-Bolivar C, Janicki SM, Greenberg RA.

Cell. 2010 Jun 11;141(6):970-81. doi: 10.1016/j.cell.2010.04.038.

10.

SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1.

Li X, Lin HH, Chen H, Xu X, Shih HM, Ann DK.

Sci Signal. 2010 Apr 27;3(119):ra32. doi: 10.1126/scisignal.2000781.

11.

SUMO and ubiquitin paths converge.

Denuc A, Marfany G.

Biochem Soc Trans. 2010 Feb;38(Pt 1):34-9. doi: 10.1042/BST0380034. Review.

PMID:
20074031
12.

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes.

Bekker-Jensen S, Rendtlew Danielsen J, Fugger K, Gromova I, Nerstedt A, Lukas C, Bartek J, Lukas J, Mailand N.

Nat Cell Biol. 2010 Jan;12(1):80-6; sup pp 1-12. doi: 10.1038/ncb2008. Epub 2009 Dec 20. Erratum in: Nat Cell Biol. 2010 Apr;12(4):412. Lukas, Claudia [added].

PMID:
20023648
13.

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.

Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, Jackson SP.

Nature. 2009 Dec 17;462(7275):935-9. doi: 10.1038/nature08657.

14.

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

Morris JR, Boutell C, Keppler M, Densham R, Weekes D, Alamshah A, Butler L, Galanty Y, Pangon L, Kiuchi T, Ng T, Solomon E.

Nature. 2009 Dec 17;462(7275):886-90. doi: 10.1038/nature08593.

PMID:
20016594
15.

The DNA-damage response in human biology and disease.

Jackson SP, Bartek J.

Nature. 2009 Oct 22;461(7267):1071-8. doi: 10.1038/nature08467. Review.

16.

The SUMO-targeted ubiquitin ligase subunit Slx5 resides in nuclear foci and at sites of DNA breaks.

Cook CE, Hochstrasser M, Kerscher O.

Cell Cycle. 2009 Apr 1;8(7):1080-9. Epub 2009 Apr 9.

17.

Genome stability roles of SUMO-targeted ubiquitin ligases.

Heideker J, Perry JJ, Boddy MN.

DNA Repair (Amst). 2009 Apr 5;8(4):517-24. doi: 10.1016/j.dnarep.2009.01.010. Epub 2009 Feb 23. Review.

18.

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.

Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R, Ellenberg J, Panier S, Durocher D, Bartek J, Lukas J, Lukas C.

Cell. 2009 Feb 6;136(3):435-46. doi: 10.1016/j.cell.2008.12.041.

19.

Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase.

Nagai S, Dubrana K, Tsai-Pflugfelder M, Davidson MB, Roberts TM, Brown GW, Varela E, Hediger F, Gasser SM, Krogan NJ.

Science. 2008 Oct 24;322(5901):597-602. doi: 10.1126/science.1162790.

20.

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer.

Lavin MF.

Nat Rev Mol Cell Biol. 2008 Oct;9(10):759-69. doi: 10.1038/nrm2514. Review. Erratum in: Nat Rev Mol Cell Biol. 2008 Dec;9(12). doi: 10.1038/nrm2514.

PMID:
18813293
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