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Results: 1 to 20 of 36

1.

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.

Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, Transy C, Landau NR, Kim B, Margottin-Goguet F.

Nat Immunol. 2012 Feb 12;13(3):223-8. doi: 10.1038/ni.2236. Erratum in: Nat Immunol. 2013 Aug;14(8):877.

PMID:
22327569
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The impact of molecular manipulation in residue 114 of human immunodeficiency virus type-1 reverse transcriptase on dNTP substrate binding and viral replication.

Van Cor-Hosmer SK, Daddacha W, Kelly Z, Tsurumi A, Kennedy EM, Kim B.

Virology. 2012 Jan 20;422(2):393-401. doi: 10.1016/j.virol.2011.11.004. Epub 2011 Dec 5.

PMID:
22153297
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Altered strand transfer activity of a multiple-drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutant with a dipeptide fingers domain insertion.

Nguyen LA, Daddacha W, Rigby S, Bambara RA, Kim B.

J Mol Biol. 2012 Jan 13;415(2):248-62. doi: 10.1016/j.jmb.2011.11.014. Epub 2011 Nov 12.

PMID:
22100453
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase.

Powell RD, Holland PJ, Hollis T, Perrino FW.

J Biol Chem. 2011 Dec 23;286(51):43596-600. doi: 10.1074/jbc.C111.317628. Epub 2011 Nov 7.

PMID:
22069334
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.

Goldstone DC, Ennis-Adeniran V, Hedden JJ, Groom HC, Rice GI, Christodoulou E, Walker PA, Kelly G, Haire LF, Yap MW, de Carvalho LP, Stoye JP, Crow YJ, Taylor IA, Webb M.

Nature. 2011 Nov 6;480(7377):379-82. doi: 10.1038/nature10623.

PMID:
22056990
[PubMed - indexed for MEDLINE]
6.

DNA building blocks: keeping control of manufacture.

Hofer A, Crona M, Logan DT, Sjöberg BM.

Crit Rev Biochem Mol Biol. 2012 Jan-Feb;47(1):50-63. doi: 10.3109/10409238.2011.630372. Epub 2011 Nov 3. Review.

PMID:
22050358
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein.

Hrecka K, Hao C, Gierszewska M, Swanson SK, Kesik-Brodacka M, Srivastava S, Florens L, Washburn MP, Skowronski J.

Nature. 2011 Jun 29;474(7353):658-61. doi: 10.1038/nature10195.

PMID:
21720370
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon.

Pertel T, Reinhard C, Luban J.

Retrovirology. 2011 Jun 22;8:49. doi: 10.1186/1742-4690-8-49.

PMID:
21696578
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A simple, versatile and efficient method to genetically modify human monocyte-derived dendritic cells with HIV-1-derived lentiviral vectors.

Berger G, Durand S, Goujon C, Nguyen XN, Cordeil S, Darlix JL, Cimarelli A.

Nat Protoc. 2011 Jun;6(6):806-16. doi: 10.1038/nprot.2011.327. Epub 2011 May 19.

PMID:
21637200
[PubMed - indexed for MEDLINE]
10.

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx.

Laguette N, Sobhian B, Casartelli N, Ringeard M, Chable-Bessia C, Ségéral E, Yatim A, Emiliani S, Schwartz O, Benkirane M.

Nature. 2011 May 25;474(7353):654-7. doi: 10.1038/nature10117.

PMID:
21613998
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells.

Sunseri N, O'Brien M, Bhardwaj N, Landau NR.

J Virol. 2011 Jul;85(13):6263-74. doi: 10.1128/JVI.00346-11. Epub 2011 Apr 20.

PMID:
21507971
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Abundant non-canonical dUTP found in primary human macrophages drives its frequent incorporation by HIV-1 reverse transcriptase.

Kennedy EM, Daddacha W, Slater R, Gavegnano C, Fromentin E, Schinazi RF, Kim B.

J Biol Chem. 2011 Jul 15;286(28):25047-55. doi: 10.1074/jbc.M111.234047. Epub 2011 Mar 31.

PMID:
21454906
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Ribonucleoside triphosphates as substrate of human immunodeficiency virus type 1 reverse transcriptase in human macrophages.

Kennedy EM, Gavegnano C, Nguyen L, Slater R, Lucas A, Fromentin E, Schinazi RF, Kim B.

J Biol Chem. 2010 Dec 10;285(50):39380-91. doi: 10.1074/jbc.M110.178582. Epub 2010 Oct 5.

PMID:
20924117
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mechanistic interplay among the M184I HIV-1 reverse transcriptase mutant, the central polypurine tract, cellular dNTP concentrations and drug sensitivity.

Van Cor-Hosmer SK, Daddacha W, Kim B.

Virology. 2010 Oct 25;406(2):253-60. doi: 10.1016/j.virol.2010.07.028. Epub 2010 Aug 10.

PMID:
20701944
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.

Casey L, Wen X, de Noronha CM.

Cytokine. 2010 Jul;51(1):1-9. doi: 10.1016/j.cyto.2010.02.018. Epub 2010 Mar 27. Review.

PMID:
20347598
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response.

Rice GI, Bond J, Asipu A, Brunette RL, Manfield IW, Carr IM, Fuller JC, Jackson RM, Lamb T, Briggs TA, Ali M, Gornall H, Couthard LR, Aeby A, Attard-Montalto SP, Bertini E, Bodemer C, Brockmann K, Brueton LA, Corry PC, Desguerre I, Fazzi E, Cazorla AG, Gener B, Hamel BC, Heiberg A, Hunter M, van der Knaap MS, Kumar R, Lagae L, Landrieu PG, Lourenco CM, Marom D, McDermott MF, van der Merwe W, Orcesi S, Prendiville JS, Rasmussen M, Shalev SA, Soler DM, Shinawi M, Spiegel R, Tan TY, Vanderver A, Wakeling EL, Wassmer E, Whittaker E, Lebon P, Stetson DB, Bonthron DT, Crow YJ.

Nat Genet. 2009 Jul;41(7):829-32. doi: 10.1038/ng.373. Epub 2009 Jun 14.

PMID:
19525956
[PubMed - indexed for MEDLINE]
17.

Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells.

Goujon C, Arfi V, Pertel T, Luban J, Lienard J, Rigal D, Darlix JL, Cimarelli A.

J Virol. 2008 Dec;82(24):12335-45. doi: 10.1128/JVI.01181-08. Epub 2008 Oct 1.

PMID:
18829761
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy.

Chugh P, Bradel-Tretheway B, Monteiro-Filho CM, Planelles V, Maggirwar SB, Dewhurst S, Kim B.

Retrovirology. 2008 Jan 31;5:11. doi: 10.1186/1742-4690-5-11.

PMID:
18237430
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Ribonucleotide reductase and the regulation of DNA replication: an old story and an ancient heritage.

Herrick J, Sclavi B.

Mol Microbiol. 2007 Jan;63(1):22-34. Review.

PMID:
17229208
[PubMed - indexed for MEDLINE]
20.

SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells.

Goujon C, Rivière L, Jarrosson-Wuilleme L, Bernaud J, Rigal D, Darlix JL, Cimarelli A.

Retrovirology. 2007 Jan 9;4:2.

PMID:
17212817
[PubMed - indexed for MEDLINE]
Free PMC Article

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