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Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy.

Sigal A, Kim JT, Balazs AB, Dekel E, Mayo A, Milo R, Baltimore D.

Nature. 2011 Aug 17;477(7362):95-8. doi: 10.1038/nature10347.


A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response.

Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, Lampiris H, Hunt PW, Palmer S, McCune JM, Martin JN, Busch MP, Shacklett BL, Deeks SG.

J Infect Dis. 2011 Apr 1;203(7):960-8. doi: 10.1093/infdis/jiq138.


Cardiovascular implications from untreated human immunodeficiency virus infection.

Baker JV, Lundgren JD.

Eur Heart J. 2011 Apr;32(8):945-51. doi: 10.1093/eurheartj/ehq483. Epub 2011 Jan 12. Review.


HIV infection, inflammation, immunosenescence, and aging.

Deeks SG.

Annu Rev Med. 2011;62:141-55. doi: 10.1146/annurev-med-042909-093756. Review.


Association of immunologic and virologic factors with myocardial infarction rates in a US healthcare system.

Triant VA, Regan S, Lee H, Sax PE, Meigs JB, Grinspoon SK.

J Acquir Immune Defic Syndr. 2010 Dec 15;55(5):615-9. doi: 10.1097/QAI.0b013e3181f4b752.


Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy.

Yukl SA, Shergill AK, McQuaid K, Gianella S, Lampiris H, Hare CB, Pandori M, Sinclair E, Günthard HF, Fischer M, Wong JK, Havlir DV.

AIDS. 2010 Oct 23;24(16):2451-60. doi: 10.1097/QAD.0b013e32833ef7bb.


The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial.

Gandhi RT, Zheng L, Bosch RJ, Chan ES, Margolis DM, Read S, Kallungal B, Palmer S, Medvik K, Lederman MM, Alatrakchi N, Jacobson JM, Wiegand A, Kearney M, Coffin JM, Mellors JW, Eron JJ; AIDS Clinical Trials Group A5244 team.

PLoS Med. 2010 Aug 10;7(8). pii: e1000321. doi: 10.1371/journal.pmed.1000321.


Low CD4+ T cell count is a risk factor for cardiovascular disease events in the HIV outpatient study.

Lichtenstein KA, Armon C, Buchacz K, Chmiel JS, Buckner K, Tedaldi EM, Wood K, Holmberg SD, Brooks JT; HIV Outpatient Study (HOPS) Investigators.

Clin Infect Dis. 2010 Aug 15;51(4):435-47. doi: 10.1086/655144.


Inflammation and mortality in HIV-infected adults: analysis of the FRAM study cohort.

Tien PC, Choi AI, Zolopa AR, Benson C, Tracy R, Scherzer R, Bacchetti P, Shlipak M, Grunfeld C.

J Acquir Immune Defic Syndr. 2010 Nov;55(3):316-22. doi: 10.1097/QAI.0b013e3181e66216.


Initiation of antiretroviral therapy at higher nadir CD4+ T-cell counts is associated with reduced arterial stiffness in HIV-infected individuals.

Ho JE, Deeks SG, Hecht FM, Xie Y, Schnell A, Martin JN, Ganz P, Hsue PY.

AIDS. 2010 Jul 31;24(12):1897-905. doi: 10.1097/QAD.0b013e32833bee44.


Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection.

Ford ES, Greenwald JH, Richterman AG, Rupert A, Dutcher L, Badralmaa Y, Natarajan V, Rehm C, Hadigan C, Sereti I.

AIDS. 2010 Jun 19;24(10):1509-17. doi: 10.1097/QAD.0b013e32833ad914.


Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection.

Neuhaus J, Jacobs DR Jr, Baker JV, Calmy A, Duprez D, La Rosa A, Kuller LH, Pett SL, Ristola M, Ross MJ, Shlipak MG, Tracy R, Neaton JD.

J Infect Dis. 2010 Jun 15;201(12):1788-95. doi: 10.1086/652749.


Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy.

McMahon D, Jones J, Wiegand A, Gange SJ, Kearney M, Palmer S, McNulty S, Metcalf JA, Acosta E, Rehm C, Coffin JM, Mellors JW, Maldarelli F.

Clin Infect Dis. 2010 Mar 15;50(6):912-9. doi: 10.1086/650749.


Coronary aging in HIV-infected patients.

Guaraldi G, Zona S, Alexopoulos N, Orlando G, Carli F, Ligabue G, Fiocchi F, Lattanzi A, Rossi R, Modena MG, Esposito R, Palella F, Raggi P.

Clin Infect Dis. 2009 Dec 1;49(11):1756-62. doi: 10.1086/648080.


Interleukin-2 therapy in patients with HIV infection.

INSIGHT-ESPRIT Study Group; SILCAAT Scientific Committee, Abrams D, Lévy Y, Losso MH, Babiker A, Collins G, Cooper DA, Darbyshire J, Emery S, Fox L, Gordin F, Lane HC, Lundgren JD, Mitsuyasu R, Neaton JD, Phillips A, Routy JP, Tambussi G, Wentworth D.

N Engl J Med. 2009 Oct 15;361(16):1548-59. doi: 10.1056/NEJMoa0903175.


Untreated HIV infection and large and small artery elasticity.

Baker JV, Duprez D, Rapkin J, Hullsiek KH, Quick H, Grimm R, Neaton JD, Henry K.

J Acquir Immune Defic Syndr. 2009 Sep 1;52(1):25-31.


Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy.

Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, O'Shea A, Callender M, Spivak A, Brennan T, Kearney MF, Proschan MA, Mican JM, Rehm CA, Coffin JM, Mellors JW, Siliciano RF, Maldarelli F.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9403-8. doi: 10.1073/pnas.0903107106. Epub 2009 May 22.


Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis.

Hsue PY, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG.

AIDS. 2009 Jun 1;23(9):1059-67. doi: 10.1097/QAD.0b013e32832b514b.


Association of C-reactive protein and HIV infection with acute myocardial infarction.

Triant VA, Meigs JB, Grinspoon SK.

J Acquir Immune Defic Syndr. 2009 Jul 1;51(3):268-73. doi: 10.1097/QAI.0b013e3181a9992c.


Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial.

Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, Macfadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Trial Study Group.

Lancet. 2009 Apr 4;373(9670):1175-82. doi: 10.1016/S0140-6736(09)60447-5. Epub 2009 Mar 28.

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