Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 38

1.

Targeting the MET oncogene in cancer and metastases.

Stella GM, Benvenuti S, Comoglio PM.

Expert Opin Investig Drugs. 2010 Nov;19(11):1381-94. doi: 10.1517/13543784.2010.522988. Epub 2010 Sep 26. Review.

PMID:
20868306
[PubMed - indexed for MEDLINE]
2.

Monovalency unleashes the full therapeutic potential of the DN-30 anti-Met antibody.

Pacchiana G, Chiriaco C, Stella MC, Petronzelli F, De Santis R, Galluzzo M, Carminati P, Comoglio PM, Michieli P, Vigna E.

J Biol Chem. 2010 Nov 12;285(46):36149-57. doi: 10.1074/jbc.M110.134031. Epub 2010 Sep 10.

PMID:
20833723
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

c-Met expression is associated with time to recurrence in patients with glioblastoma multiforme.

Liu W, Fu Y, Xu S, Ding F, Zhao G, Zhang K, Du C, Pang B, Pang Q.

J Clin Neurosci. 2011 Jan;18(1):119-21. doi: 10.1016/j.jocn.2010.05.010. Epub 2010 Sep 15.

PMID:
20832323
[PubMed - indexed for MEDLINE]
4.

TAK-701, a humanized monoclonal antibody to hepatocyte growth factor, reverses gefitinib resistance induced by tumor-derived HGF in non-small cell lung cancer with an EGFR mutation.

Okamoto W, Okamoto I, Tanaka K, Hatashita E, Yamada Y, Kuwata K, Yamaguchi H, Arao T, Nishio K, Fukuoka M, Jänne PA, Nakagawa K.

Mol Cancer Ther. 2010 Oct;9(10):2785-92. doi: 10.1158/1535-7163.MCT-10-0481. Epub 2010 Aug 17.

PMID:
20716641
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma.

Bu R, Uddin S, Bavi P, Hussain AR, Al-Dayel F, Ghourab S, Ahmed M, Al-Kuraya KS.

Lab Invest. 2011 Jan;91(1):124-37. doi: 10.1038/labinvest.2010.136. Epub 2010 Jul 26.

PMID:
20661229
[PubMed - indexed for MEDLINE]
Free Article
6.

A disintegrin and metalloproteinase-10 (ADAM-10) mediates DN30 antibody-induced shedding of the met surface receptor.

Schelter F, Kobuch J, Moss ML, Becherer JD, Comoglio PM, Boccaccio C, Krüger A.

J Biol Chem. 2010 Aug 20;285(34):26335-40. doi: 10.1074/jbc.M110.106435. Epub 2010 Jun 16.

PMID:
20554517
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Rilotumumab, a mAb against human hepatocyte growth factor for the treatment of cancer.

Giordano S.

Curr Opin Mol Ther. 2009 Aug;11(4):448-55.

PMID:
19649990
[PubMed - indexed for MEDLINE]
8.

The plasticity of oncogene addiction: implications for targeted therapies directed to receptor tyrosine kinases.

Pillay V, Allaf L, Wilding AL, Donoghue JF, Court NW, Greenall SA, Scott AM, Johns TG.

Neoplasia. 2009 May;11(5):448-58, 2 p following 458.

PMID:
19412429
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A truncated soluble epidermal growth factor receptor-Fc fusion ligand trap displays anti-tumour activity in vivo.

Adams TE, Koziolek EJ, Hoyne PH, Bentley JD, Lu L, Lovrecz G, Ward CW, Lee FT, Scott AM, Nash AD, Rothacker J, Nice EC, Burgess AW, Johns TG.

Growth Factors. 2009 Jun;27(3):141-54. doi: 10.1080/08977190902843565.

PMID:
19333814
[PubMed - indexed for MEDLINE]
10.

Novel therapeutic inhibitors of the c-Met signaling pathway in cancer.

Eder JP, Vande Woude GF, Boerner SA, LoRusso PM.

Clin Cancer Res. 2009 Apr 1;15(7):2207-14. doi: 10.1158/1078-0432.CCR-08-1306. Epub 2009 Mar 24. Review.

PMID:
19318488
[PubMed - indexed for MEDLINE]
Free Article
11.

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR.

Garrett TP, Burgess AW, Gan HK, Luwor RB, Cartwright G, Walker F, Orchard SG, Clayton AH, Nice EC, Rothacker J, Catimel B, Cavenee WK, Old LJ, Stockert E, Ritter G, Adams TE, Hoyne PA, Wittrup D, Chao G, Cochran JR, Luo C, Lou M, Huyton T, Xu Y, Fairlie WD, Yao S, Scott AM, Johns TG.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5082-7. doi: 10.1073/pnas.0811559106. Epub 2009 Mar 16.

PMID:
19289842
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Prognostic significance of c-Met expression in glioblastomas.

Kong DS, Song SY, Kim DH, Joo KM, Yoo JS, Koh JS, Dong SM, Suh YL, Lee JI, Park K, Kim JH, Nam DH.

Cancer. 2009 Jan 1;115(1):140-8. doi: 10.1002/cncr.23972.

PMID:
18973197
[PubMed - indexed for MEDLINE]
Free Article
13.

Derailed endocytosis: an emerging feature of cancer.

Mosesson Y, Mills GB, Yarden Y.

Nat Rev Cancer. 2008 Nov;8(11):835-50. doi: 10.1038/nrc2521. Review.

PMID:
18948996
[PubMed - indexed for MEDLINE]
14.

MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival.

Jin H, Yang R, Zheng Z, Romero M, Ross J, Bou-Reslan H, Carano RA, Kasman I, Mai E, Young J, Zha J, Zhang Z, Ross S, Schwall R, Colbern G, Merchant M.

Cancer Res. 2008 Jun 1;68(11):4360-8. doi: 10.1158/0008-5472.CAN-07-5960.

PMID:
18519697
[PubMed - indexed for MEDLINE]
Free Article
15.

Drug development of MET inhibitors: targeting oncogene addiction and expedience.

Comoglio PM, Giordano S, Trusolino L.

Nat Rev Drug Discov. 2008 Jun;7(6):504-16. doi: 10.1038/nrd2530. Review.

PMID:
18511928
[PubMed - indexed for MEDLINE]
16.

c-Met must translocate to the nucleus to initiate calcium signals.

Gomes DA, Rodrigues MA, Leite MF, Gomez MV, Varnai P, Balla T, Bennett AM, Nathanson MH.

J Biol Chem. 2008 Feb 15;283(7):4344-51. Epub 2007 Dec 11.

PMID:
18073207
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Inference of macromolecular assemblies from crystalline state.

Krissinel E, Henrick K.

J Mol Biol. 2007 Sep 21;372(3):774-97. Epub 2007 May 13.

PMID:
17681537
[PubMed - indexed for MEDLINE]
18.

FireDock: fast interaction refinement in molecular docking.

Andrusier N, Nussinov R, Wolfson HJ.

Proteins. 2007 Oct 1;69(1):139-59.

PMID:
17598144
[PubMed - indexed for MEDLINE]
19.

A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo.

Martens T, Schmidt NO, Eckerich C, Fillbrandt R, Merchant M, Schwall R, Westphal M, Lamszus K.

Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6144-52.

PMID:
17062691
[PubMed - indexed for MEDLINE]
Free Article
20.

Ab-induced ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activity.

Petrelli A, Circosta P, Granziero L, Mazzone M, Pisacane A, Fenoglio S, Comoglio PM, Giordano S.

Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5090-5. Epub 2006 Mar 17.

PMID:
16547140
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk