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Results: 1 to 20 of 38

1.

Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways.

Eleftherohorinou H, Hoggart CJ, Wright VJ, Levin M, Coin LJ.

Hum Mol Genet. 2011 Sep 1;20(17):3494-506. doi: 10.1093/hmg/ddr248. Epub 2011 Jun 8.

PMID:
21653640
[PubMed - indexed for MEDLINE]
Free Article
2.

Gene set analysis of SNP data: benefits, challenges, and future directions.

Fridley BL, Biernacka JM.

Eur J Hum Genet. 2011 Aug;19(8):837-43. doi: 10.1038/ejhg.2011.57. Epub 2011 Apr 13. Review.

PMID:
21487444
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Biological pathway selection through nonlinear dimension reduction.

Zhu H, Li L.

Biostatistics. 2011 Jul;12(3):429-44. doi: 10.1093/biostatistics/kxq081. Epub 2011 Jan 20.

PMID:
21252081
[PubMed - indexed for MEDLINE]
Free Article
4.

Pathway-based analysis using reduced gene subsets in genome-wide association studies.

Zhao J, Gupta S, Seielstad M, Liu J, Thalamuthu A.

BMC Bioinformatics. 2011 Jan 12;12:17. doi: 10.1186/1471-2105-12-17.

PMID:
21226955
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Analysing biological pathways in genome-wide association studies.

Wang K, Li M, Hakonarson H.

Nat Rev Genet. 2010 Dec;11(12):843-54. doi: 10.1038/nrg2884. Review.

PMID:
21085203
[PubMed - indexed for MEDLINE]
6.

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, König IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Müller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpeläinen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Paré G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietiläinen KH, Pouta A, Ridderstråle M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kähönen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimäki T, Melander O, Mosley TH Jr, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tönjes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Grönberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Völzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN.

Nature. 2010 Oct 14;467(7317):832-8. doi: 10.1038/nature09410. Epub 2010 Sep 29.

PMID:
20881960
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Association screening of common and rare genetic variants by penalized regression.

Zhou H, Sehl ME, Sinsheimer JS, Lange K.

Bioinformatics. 2010 Oct 1;26(19):2375-82. doi: 10.1093/bioinformatics/btq448. Epub 2010 Aug 6.

PMID:
20693321
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Penalized methods for bi-level variable selection.

Breheny P, Huang J.

Stat Interface. 2009 Jul 1;2(3):369-380.

PMID:
20640242
[PubMed]
Free PMC Article
9.

Discovering genetic associations with high-dimensional neuroimaging phenotypes: A sparse reduced-rank regression approach.

Vounou M, Nichols TE, Montana G; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage. 2010 Nov 15;53(3):1147-59. doi: 10.1016/j.neuroimage.2010.07.002. Epub 2010 Jul 17.

PMID:
20624472
[PubMed - indexed for MEDLINE]
10.

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries.

Park JH, Wacholder S, Gail MH, Peters U, Jacobs KB, Chanock SJ, Chatterjee N.

Nat Genet. 2010 Jul;42(7):570-5. doi: 10.1038/ng.610. Epub 2010 Jun 20.

PMID:
20562874
[PubMed - indexed for MEDLINE]
11.

Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data.

Chen LS, Hutter CM, Potter JD, Liu Y, Prentice RL, Peters U, Hsu L.

Am J Hum Genet. 2010 Jun 11;86(6):860-71. doi: 10.1016/j.ajhg.2010.04.014.

PMID:
20560206
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ontologies in quantitative biology: a basis for comparison, integration, and discovery.

Jensen LJ, Bork P.

PLoS Biol. 2010 May 25;8(5):e1000374. doi: 10.1371/journal.pbio.1000374. No abstract available.

PMID:
20520843
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A human functional protein interaction network and its application to cancer data analysis.

Wu G, Feng X, Stein L.

Genome Biol. 2010;11(5):R53. doi: 10.1186/gb-2010-11-5-r53. Epub 2010 May 19.

PMID:
20482850
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Pathway analysis of breast cancer genome-wide association study highlights three pathways and one canonical signaling cascade.

Menashe I, Maeder D, Garcia-Closas M, Figueroa JD, Bhattacharjee S, Rotunno M, Kraft P, Hunter DJ, Chanock SJ, Rosenberg PS, Chatterjee N.

Cancer Res. 2010 Jun 1;70(11):4453-9. doi: 10.1158/0008-5472.CAN-09-4502. Epub 2010 May 11.

PMID:
20460509
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Genome-wide gene and pathway analysis.

Luo L, Peng G, Zhu Y, Dong H, Amos CI, Xiong M.

Eur J Hum Genet. 2010 Sep;18(9):1045-53. doi: 10.1038/ejhg.2010.62. Epub 2010 May 5.

PMID:
20442747
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Implication of the immune system in Alzheimer's disease: evidence from genome-wide pathway analysis.

Lambert JC, Grenier-Boley B, Chouraki V, Heath S, Zelenika D, Fievet N, Hannequin D, Pasquier F, Hanon O, Brice A, Epelbaum J, Berr C, Dartigues JF, Tzourio C, Campion D, Lathrop M, Amouyel P.

J Alzheimers Dis. 2010;20(4):1107-18. doi: 10.3233/JAD-2010-100018.

PMID:
20413860
[PubMed - indexed for MEDLINE]
17.

Imaging genetics--days of future past.

Bigos KL, Weinberger DR.

Neuroimage. 2010 Nov 15;53(3):804-9. doi: 10.1016/j.neuroimage.2010.01.035. Epub 2010 Jan 18. Review.

PMID:
20080192
[PubMed - indexed for MEDLINE]
18.

Prioritizing GWAS results: A review of statistical methods and recommendations for their application.

Cantor RM, Lange K, Sinsheimer JS.

Am J Hum Genet. 2010 Jan;86(1):6-22. doi: 10.1016/j.ajhg.2009.11.017. Review.

PMID:
20074509
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Detection of gene pathways with predictive power for breast cancer prognosis.

Ma S, Kosorok MR.

BMC Bioinformatics. 2010 Jan 1;11:1. doi: 10.1186/1471-2105-11-1.

PMID:
20043860
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.

Eleftherohorinou H, Wright V, Hoggart C, Hartikainen AL, Jarvelin MR, Balding D, Coin L, Levin M.

PLoS One. 2009 Nov 30;4(11):e8068. doi: 10.1371/journal.pone.0008068.

PMID:
19956648
[PubMed - indexed for MEDLINE]
Free PMC Article

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