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Results: 1 to 20 of 54

1.

Automated minimization of steric clashes in protein structures.

Ramachandran S, Kota P, Ding F, Dokholyan NV.

Proteins. 2011 Jan;79(1):261-70. doi: 10.1002/prot.22879.

PMID:
21058396
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel.

Gentzsch M, Dang H, Dang Y, Garcia-Caballero A, Suchindran H, Boucher RC, Stutts MJ.

J Biol Chem. 2010 Oct 15;285(42):32227-32. doi: 10.1074/jbc.M110.155259. Epub 2010 Aug 13.

PMID:
20709758
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Extracellular allosteric regulatory subdomain within the gamma subunit of the epithelial Na+ channel.

Winarski KL, Sheng N, Chen J, Kleyman TR, Sheng S.

J Biol Chem. 2010 Aug 20;285(34):26088-96. doi: 10.1074/jbc.M110.149963. Epub 2010 Jun 29.

PMID:
20587418
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases.

Gaillard EA, Kota P, Gentzsch M, Dokholyan NV, Stutts MJ, Tarran R.

Pflugers Arch. 2010 Jun;460(1):1-17. doi: 10.1007/s00424-010-0827-z. Epub 2010 Apr 18. Review.

PMID:
20401730
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Prostasin-dependent activation of epithelial Na+ channels by low plasmin concentrations.

Svenningsen P, Uhrenholt TR, Palarasah Y, Skjødt K, Jensen BL, Skøtt O.

Am J Physiol Regul Integr Comp Physiol. 2009 Dec;297(6):R1733-41. doi: 10.1152/ajpregu.00321.2009. Epub 2009 Sep 30.

PMID:
19793956
[PubMed - indexed for MEDLINE]
Free Article
6.

Type II transmembrane serine proteases.

Bugge TH, Antalis TM, Wu Q.

J Biol Chem. 2009 Aug 28;284(35):23177-81. doi: 10.1074/jbc.R109.021006. Epub 2009 Jun 1. Review.

PMID:
19487698
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

ENaC at the cutting edge: regulation of epithelial sodium channels by proteases.

Kleyman TR, Carattino MD, Hughey RP.

J Biol Chem. 2009 Jul 31;284(31):20447-51. doi: 10.1074/jbc.R800083200. Epub 2009 Apr 28. Review.

PMID:
19401469
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Activation of a membrane-bound serine protease matriptase on the cell surface.

Miyake Y, Yasumoto M, Tsuzuki S, Fushiki T, Inouye K.

J Biochem. 2009 Aug;146(2):273-82. doi: 10.1093/jb/mvp066. Epub 2009 Apr 26.

PMID:
19398443
[PubMed - indexed for MEDLINE]
9.

Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epithelium.

Kim SH, Kim KX, Raveendran NN, Wu T, Pondugula SR, Marcus DC.

Am J Physiol Cell Physiol. 2009 Mar;296(3):C544-57. doi: 10.1152/ajpcell.00338.2008. Epub 2009 Jan 14.

PMID:
19144862
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Plasmin activates epithelial Na+ channels by cleaving the gamma subunit.

Passero CJ, Mueller GM, Rondon-Berrios H, Tofovic SP, Hughey RP, Kleyman TR.

J Biol Chem. 2008 Dec 26;283(52):36586-91. doi: 10.1074/jbc.M805676200. Epub 2008 Nov 3.

PMID:
18981180
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Effect of cytosolic pH on epithelial Na+ channel in normal and cystic fibrosis sweat ducts.

Reddy MM, Wang XF, Quinton PM.

J Membr Biol. 2008 Sep-Oct;225(1-3):1-11. doi: 10.1007/s00232-008-9126-4. Epub 2008 Oct 21.

PMID:
18937003
[PubMed - indexed for MEDLINE]
12.

Activation of the epithelial sodium channel (ENaC) by serine proteases.

Rossier BC, Stutts MJ.

Annu Rev Physiol. 2009;71:361-79. doi: 10.1146/annurev.physiol.010908.163108. Review.

PMID:
18928407
[PubMed - indexed for MEDLINE]
13.

ENaC proteolytic regulation by channel-activating protease 2.

García-Caballero A, Dang Y, He H, Stutts MJ.

J Gen Physiol. 2008 Nov;132(5):521-35. doi: 10.1085/jgp.200810030. Epub 2008 Oct 13.

PMID:
18852303
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Potent inhibition and global co-localization implicate the transmembrane Kunitz-type serine protease inhibitor hepatocyte growth factor activator inhibitor-2 in the regulation of epithelial matriptase activity.

Szabo R, Hobson JP, List K, Molinolo A, Lin CY, Bugge TH.

J Biol Chem. 2008 Oct 24;283(43):29495-504. doi: 10.1074/jbc.M801970200. Epub 2008 Aug 19.

PMID:
18713750
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels.

Diakov A, Bera K, Mokrushina M, Krueger B, Korbmacher C.

J Physiol. 2008 Oct 1;586(Pt 19):4587-608. doi: 10.1113/jphysiol.2008.154435. Epub 2008 Jul 31.

PMID:
18669538
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Ab initio folding of proteins with all-atom discrete molecular dynamics.

Ding F, Tsao D, Nie H, Dokholyan NV.

Structure. 2008 Jul;16(7):1010-8. doi: 10.1016/j.str.2008.03.013.

PMID:
18611374
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Insight toward epithelial Na+ channel mechanism revealed by the acid-sensing ion channel 1 structure.

Stockand JD, Staruschenko A, Pochynyuk O, Booth RE, Silverthorn DU.

IUBMB Life. 2008 Sep;60(9):620-8. doi: 10.1002/iub.89. Review.

PMID:
18459164
[PubMed - indexed for MEDLINE]
18.

Type II transmembrane serine proteases in development and disease.

Szabo R, Bugge TH.

Int J Biochem Cell Biol. 2008;40(6-7):1297-316. doi: 10.1016/j.biocel.2007.11.013. Epub 2007 Dec 4. Review.

PMID:
18191610
[PubMed - indexed for MEDLINE]
19.

A segment of gamma ENaC mediates elastase activation of Na+ transport.

Adebamiro A, Cheng Y, Rao US, Danahay H, Bridges RJ.

J Gen Physiol. 2007 Dec;130(6):611-29. Epub 2007 Nov 12.

PMID:
17998393
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH.

Jasti J, Furukawa H, Gonzales EB, Gouaux E.

Nature. 2007 Sep 20;449(7160):316-23.

PMID:
17882215
[PubMed - indexed for MEDLINE]

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