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Results: 1 to 20 of 69

1.

Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.

Gallego X, Molas S, Amador-Arjona A, Marks MJ, Robles N, Murtra P, Armengol L, Fernández-Montes RD, Gratacòs M, Pumarola M, Cabrera R, Maldonado R, Sabrià J, Estivill X, Dierssen M.

Amino Acids. 2012 Aug;43(2):897-909. doi: 10.1007/s00726-011-1149-y. Epub 2011 Nov 19.

PMID:
22101982
[PubMed - indexed for MEDLINE]
2.

Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula.

Frahm S, Slimak MA, Ferrarese L, Santos-Torres J, Antolin-Fontes B, Auer S, Filkin S, Pons S, Fontaine JF, Tsetlin V, Maskos U, Ibañez-Tallon I.

Neuron. 2011 May 12;70(3):522-35. doi: 10.1016/j.neuron.2011.04.013.

PMID:
21555077
[PubMed - indexed for MEDLINE]
Free Article
3.

Varenicline, a partial agonist at neuronal nicotinic acetylcholine receptors, reduces nicotine-induced increases in 20% ethanol operant self-administration in Sprague-Dawley rats.

Bito-Onon JJ, Simms JA, Chatterjee S, Holgate J, Bartlett SE.

Addict Biol. 2011 Jul;16(3):440-9. doi: 10.1111/j.1369-1600.2010.00309.x. Epub 2011 Mar 11.

PMID:
21392178
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Habenular α5 nicotinic receptor subunit signalling controls nicotine intake.

Fowler CD, Lu Q, Johnson PM, Marks MJ, Kenny PJ.

Nature. 2011 Mar 31;471(7340):597-601. doi: 10.1038/nature09797. Epub 2011 Jan 30.

PMID:
21278726
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Alcohol preference drinking in a mouse line selectively bred for high drinking in the dark.

Crabbe JC, Spence SE, Brown LL, Metten P.

Alcohol. 2011 Aug;45(5):427-40. doi: 10.1016/j.alcohol.2010.12.001. Epub 2010 Dec 30.

PMID:
21194877
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats.

Chatterjee S, Steensland P, Simms JA, Holgate J, Coe JW, Hurst RS, Shaffer CL, Lowe J, Rollema H, Bartlett SE.

Neuropsychopharmacology. 2011 Feb;36(3):603-15. doi: 10.1038/npp.2010.191. Epub 2010 Nov 3.

PMID:
21048701
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Promoter polymorphisms and transcript levels of nicotinic receptor CHRNA5.

Falvella FS, Galvan A, Colombo F, Frullanti E, Pastorino U, Dragani TA.

J Natl Cancer Inst. 2010 Sep 8;102(17):1366-70. doi: 10.1093/jnci/djq264. Epub 2010 Aug 23.

PMID:
20733116
[PubMed - indexed for MEDLINE]
Free Article
8.

Nicotinic acetylcholine receptor genes on chromosome 15q25.1 are associated with nicotine and opioid dependence severity.

Erlich PM, Hoffman SN, Rukstalis M, Han JJ, Chu X, Linda Kao WH, Gerhard GS, Stewart WF, Boscarino JA.

Hum Genet. 2010 Nov;128(5):491-9. doi: 10.1007/s00439-010-0876-6. Epub 2010 Aug 20.

PMID:
20725741
[PubMed - indexed for MEDLINE]
9.

Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes.

Grucza RA, Johnson EO, Krueger RF, Breslau N, Saccone NL, Chen LS, Derringer J, Agrawal A, Lynskey M, Bierut LJ.

Addict Biol. 2010 Jul;15(3):346-57. doi: 10.1111/j.1369-1600.2010.00220.x.

PMID:
20624154
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Delineation of the role of nicotinic acetylcholine receptor genes in alcohol preference in mice.

Symons MN, Weng J, Diehl E, Heo E, Kleiber ML, Singh SM.

Behav Genet. 2010 Sep;40(5):660-71. doi: 10.1007/s10519-010-9366-9. Epub 2010 May 23.

PMID:
20496163
[PubMed - indexed for MEDLINE]
11.

Nicotine addiction and nicotinic receptors: lessons from genetically modified mice.

Changeux JP.

Nat Rev Neurosci. 2010 Jun;11(6):389-401. doi: 10.1038/nrn2849. Review.

PMID:
20485364
[PubMed - indexed for MEDLINE]
12.

Nicotinic acetylcholine receptors of the dorsal hippocampus and the basolateral amygdala are involved in ethanol-induced conditioned place preference.

Zarrindast MR, Meshkani J, Rezayof A, Beigzadeh R, Rostami P.

Neuroscience. 2010 Jun 30;168(2):505-13. doi: 10.1016/j.neuroscience.2010.03.019. Epub 2010 Apr 8.

PMID:
20381593
[PubMed - indexed for MEDLINE]
13.

Inhibitory influence of mecamylamine on ethanol withdrawal-induced symptoms in C57BL/6J mice.

Bhutada PS, Mundhada YR, Bansod KU, Umathe SN, Kahale VP, Dixit PV, Mundhada DR.

Behav Pharmacol. 2010 Mar;21(2):90-5. doi: 10.1097/FBP.0b013e328337be54.

PMID:
20168214
[PubMed - indexed for MEDLINE]
14.

Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25.

Bierut LJ.

Trends Pharmacol Sci. 2010 Jan;31(1):46-51. doi: 10.1016/j.tips.2009.10.004. Epub 2009 Nov 5. Review.

PMID:
19896728
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The genetic components of alcohol and nicotine co-addiction: from genes to behavior.

Schlaepfer IR, Hoft NR, Ehringer MA.

Curr Drug Abuse Rev. 2008 Jun;1(2):124-34. Review.

PMID:
19492010
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes.

Baker TB, Weiss RB, Bolt D, von Niederhausern A, Fiore MC, Dunn DM, Piper ME, Matsunami N, Smith SS, Coon H, McMahon WM, Scholand MB, Singh N, Hoidal JR, Kim SY, Leppert MF, Cannon DS.

Nicotine Tob Res. 2009 Jul;11(7):785-96. doi: 10.1093/ntr/ntp064. Epub 2009 May 12.

PMID:
19436041
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.

Saccone NL, Saccone SF, Hinrichs AL, Stitzel JA, Duan W, Pergadia ML, Agrawal A, Breslau N, Grucza RA, Hatsukami D, Johnson EO, Madden PA, Swan GE, Wang JC, Goate AM, Rice JP, Bierut LJ.

Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 5;150B(4):453-66. doi: 10.1002/ajmg.b.30828.

PMID:
19259974
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J mice.

Hendrickson LM, Zhao-Shea R, Tapper AR.

Psychopharmacology (Berl). 2009 Jul;204(4):563-72. doi: 10.1007/s00213-009-1488-5. Epub 2009 Feb 27.

PMID:
19247637
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence.

Chen X, Chen J, Williamson VS, An SS, Hettema JM, Aggen SH, Neale MC, Kendler KS.

Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5;150B(7):926-33. doi: 10.1002/ajmg.b.30919.

PMID:
19132693
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans.

Joslyn G, Brush G, Robertson M, Smith TL, Kalmijn J, Schuckit M, White RL.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20368-73. doi: 10.1073/pnas.0810970105. Epub 2008 Dec 8.

PMID:
19064933
[PubMed - indexed for MEDLINE]
Free PMC Article

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