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Items: 1 to 20 of 46


Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG.

Li X, He L, Che KH, Funderburk SF, Pan L, Pan N, Zhang M, Yue Z, Zhao Y.

Nat Commun. 2012 Feb 7;3:662. doi: 10.1038/ncomms1648.


Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein.

Huang W, Choi W, Hu W, Mi N, Guo Q, Ma M, Liu M, Tian Y, Lu P, Wang FL, Deng H, Liu L, Gao N, Yu L, Shi Y.

Cell Res. 2012 Mar;22(3):473-89. doi: 10.1038/cr.2012.24. Epub 2012 Feb 7.


The role of Atg proteins in autophagosome formation.

Mizushima N, Yoshimori T, Ohsumi Y.

Annu Rev Cell Dev Biol. 2011;27:107-32. doi: 10.1146/annurev-cellbio-092910-154005. Epub 2011 Jul 18. Review.


Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

Matsunaga K, Morita E, Saitoh T, Akira S, Ktistakis NT, Izumi T, Noda T, Yoshimori T.

J Cell Biol. 2010 Aug 23;190(4):511-21. doi: 10.1083/jcb.200911141. Epub 2010 Aug 16.


Features and development of Coot.

Emsley P, Lohkamp B, Scott WG, Cowtan K.

Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501. doi: 10.1107/S0907444910007493. Epub 2010 Mar 24.


The emerging mechanisms of isoform-specific PI3K signalling.

Vanhaesebroeck B, Guillermet-Guibert J, Graupera M, Bilanges B.

Nat Rev Mol Cell Biol. 2010 May;11(5):329-41. doi: 10.1038/nrm2882. Epub 2010 Apr 9. Review.


Current knowledge of the pre-autophagosomal structure (PAS).

Suzuki K, Ohsumi Y.

FEBS Lett. 2010 Apr 2;584(7):1280-6. doi: 10.1016/j.febslet.2010.02.001. Epub 2010 Feb 5. Review.


Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes.

Simonsen A, Tooze SA.

J Cell Biol. 2009 Sep 21;186(6):773-82. doi: 10.1083/jcb.200907014. Review.


Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, Kurotori N, Maejima I, Shirahama-Noda K, Ichimura T, Isobe T, Akira S, Noda T, Yoshimori T.

Nat Cell Biol. 2009 Apr;11(4):385-96. doi: 10.1038/ncb1846. Epub 2009 Mar 8.


Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.

Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z.

Nat Cell Biol. 2009 Apr;11(4):468-76. doi: 10.1038/ncb1854. Epub 2009 Mar 8.


The quantitative Pho8Delta60 assay of nonspecific autophagy.

Noda T, Klionsky DJ.

Methods Enzymol. 2008;451:33-42. doi: 10.1016/S0076-6879(08)03203-5.


Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase.

Sun Q, Fan W, Chen K, Ding X, Chen S, Zhong Q.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19211-6. doi: 10.1073/pnas.0810452105. Epub 2008 Dec 2.


Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.

Itakura E, Kishi C, Inoue K, Mizushima N.

Mol Biol Cell. 2008 Dec;19(12):5360-72. doi: 10.1091/mbc.E08-01-0080. Epub 2008 Oct 8.


Searching protein structure databases with DaliLite v.3.

Holm L, Kääriäinen S, Rosenström P, Schenkel A.

Bioinformatics. 2008 Dec 1;24(23):2780-1. doi: 10.1093/bioinformatics/btn507. Epub 2008 Sep 25.


Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11.

Sinha S, Colbert CL, Becker N, Wei Y, Levine B.

Autophagy. 2008 Nov;4(8):989-97. Epub 2008 Nov 18. Erratum in: Autophagy.2009 Feb;5(2):284.


Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum.

Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT.

J Cell Biol. 2008 Aug 25;182(4):685-701. doi: 10.1083/jcb.200803137.


The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function.

Obara K, Sekito T, Niimi K, Ohsumi Y.

J Biol Chem. 2008 Aug 29;283(35):23972-80. doi: 10.1074/jbc.M803180200. Epub 2008 Jun 27.


Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae.

Obara K, Noda T, Niimi K, Ohsumi Y.

Genes Cells. 2008 Jun;13(6):537-47. doi: 10.1111/j.1365-2443.2008.01188.x.


Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL-2 of murine gamma-herpesvirus 68.

Ku B, Woo JS, Liang C, Lee KH, Hong HS, E X, Kim KS, Jung JU, Oh BH.

PLoS Pathog. 2008 Feb 8;4(2):e25. doi: 10.1371/journal.ppat.0040025.


Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein.

Cao Y, Klionsky DJ.

Cell Res. 2007 Oct;17(10):839-49. Review.

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