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Results: 1 to 20 of 46

1.
2.

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data.

C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC), Wensley F, Gao P, Burgess S, Kaptoge S, Di Angelantonio E, Shah T, Engert JC, Clarke R, Davey-Smith G, Nordestgaard BG, Saleheen D, Samani NJ, Sandhu M, Anand S, Pepys MB, Smeeth L, Whittaker J, Casas JP, Thompson SG, Hingorani AD, Danesh J.

BMJ. 2011 Feb 15;342:d548. doi: 10.1136/bmj.d548.

PMID:
21325005
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Association of IL-6 and IL-6R gene polymorphisms with susceptibility to respiratory tract infections in young Finnish men.

Rantala A, Lajunen T, Juvonen R, Silvennoinen-Kassinen S, Peitso A, Vainio O, Saikku P, Leinonen M.

Hum Immunol. 2011 Jan;72(1):63-8. doi: 10.1016/j.humimm.2010.10.010. Epub 2010 Oct 15.

PMID:
20951753
[PubMed - indexed for MEDLINE]
4.

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.

Thye T, Vannberg FO, Wong SH, Owusu-Dabo E, Osei I, Gyapong J, Sirugo G, Sisay-Joof F, Enimil A, Chinbuah MA, Floyd S, Warndorff DK, Sichali L, Malema S, Crampin AC, Ngwira B, Teo YY, Small K, Rockett K, Kwiatkowski D, Fine PE, Hill PC, Newport M, Lienhardt C, Adegbola RA, Corrah T, Ziegler A; African TB Genetics Consortium; Wellcome Trust Case Control Consortium, Morris AP, Meyer CG, Horstmann RD, Hill AV.

Nat Genet. 2010 Sep;42(9):739-41. doi: 10.1038/ng.639. Epub 2010 Aug 8. Erratum in: Nat Genet. 2011 Oct;43(10):1040.

PMID:
20694014
[PubMed - indexed for MEDLINE]
5.

Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease.

Davila S, Wright VJ, Khor CC, Sim KS, Binder A, Breunis WB, Inwald D, Nadel S, Betts H, Carrol ED, de Groot R, Hermans PW, Hazelzet J, Emonts M, Lim CC, Kuijpers TW, Martinon-Torres F, Salas A, Zenz W, Levin M, Hibberd ML; International Meningococcal Genetics Consortium.

Nat Genet. 2010 Sep;42(9):772-6. doi: 10.1038/ng.640. Epub 2010 Aug 8.

PMID:
20694013
[PubMed - indexed for MEDLINE]
6.

Tocilizumab for rheumatoid arthritis.

Singh JA, Beg S, Lopez-Olivo MA.

Cochrane Database Syst Rev. 2010 Jul 7;(7):CD008331. doi: 10.1002/14651858.CD008331.pub2. Review.

PMID:
20614469
[PubMed - indexed for MEDLINE]
7.

Safety and efficacy profiles of tocilizumab monotherapy in Japanese patients with rheumatoid arthritis: meta-analysis of six initial trials and five long-term extensions.

Nishimoto N, Ito K, Takagi N.

Mod Rheumatol. 2010 Jun;20(3):222-32. doi: 10.1007/s10165-010-0279-5. Epub 2010 Mar 11.

PMID:
20221663
[PubMed - indexed for MEDLINE]
8.

Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms.

Sofat R, Hingorani AD, Smeeth L, Humphries SE, Talmud PJ, Cooper J, Shah T, Sandhu MS, Ricketts SL, Boekholdt SM, Wareham N, Khaw KT, Kumari M, Kivimaki M, Marmot M, Asselbergs FW, van der Harst P, Dullaart RP, Navis G, van Veldhuisen DJ, Van Gilst WH, Thompson JF, McCaskie P, Palmer LJ, Arca M, Quagliarini F, Gaudio C, Cambien F, Nicaud V, Poirer O, Gudnason V, Isaacs A, Witteman JC, van Duijn CM, Pencina M, Vasan RS, D'Agostino RB Sr, Ordovas J, Li TY, Kakko S, Kauma H, Savolainen MJ, Kesäniemi YA, Sandhofer A, Paulweber B, Sorli JV, Goto A, Yokoyama S, Okumura K, Horne BD, Packard C, Freeman D, Ford I, Sattar N, McCormack V, Lawlor DA, Ebrahim S, Smith GD, Kastelein JJ, Deanfield J, Casas JP.

Circulation. 2010 Jan 5;121(1):52-62. doi: 10.1161/CIRCULATIONAHA.109.865444. Epub 2009 Dec 21. Erratum in: Circulation. 2010 Feb 23;121(7):e216.

PMID:
20026784
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

ADAM17-mediated shedding of the IL6R induces cleavage of the membrane stub by gamma-secretase.

Chalaris A, Gewiese J, Paliga K, Fleig L, Schneede A, Krieger K, Rose-John S, Scheller J.

Biochim Biophys Acta. 2010 Feb;1803(2):234-45. doi: 10.1016/j.bbamcr.2009.12.001. Epub 2009 Dec 21.

PMID:
20026129
[PubMed - indexed for MEDLINE]
Free Article
10.

Effects of the anti-interleukin-6 receptor antibody, tocilizumab, on serum lipid levels in patients with rheumatoid arthritis.

Kawashiri SY, Kawakami A, Yamasaki S, Imazato T, Iwamoto N, Fujikawa K, Aramaki T, Tamai M, Nakamura H, Ida H, Origuchi T, Ueki Y, Eguchi K.

Rheumatol Int. 2011 Apr;31(4):451-6. doi: 10.1007/s00296-009-1303-y. Epub 2009 Dec 19.

PMID:
20024554
[PubMed - indexed for MEDLINE]
11.

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.

Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group.

PLoS Med. 2009 Jul 21;6(7):e1000097. doi: 10.1371/journal.pmed.1000097. Epub 2009 Jul 21. No abstract available.

PMID:
19621072
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.

Elliott P, Chambers JC, Zhang W, Clarke R, Hopewell JC, Peden JF, Erdmann J, Braund P, Engert JC, Bennett D, Coin L, Ashby D, Tzoulaki I, Brown IJ, Mt-Isa S, McCarthy MI, Peltonen L, Freimer NB, Farrall M, Ruokonen A, Hamsten A, Lim N, Froguel P, Waterworth DM, Vollenweider P, Waeber G, Jarvelin MR, Mooser V, Scott J, Hall AS, Schunkert H, Anand SS, Collins R, Samani NJ, Watkins H, Kooner JS.

JAMA. 2009 Jul 1;302(1):37-48. doi: 10.1001/jama.2009.954.

PMID:
19567438
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events?

Sattar N, Murray HM, Welsh P, Blauw GJ, Buckley BM, Cobbe S, de Craen AJ, Lowe GD, Jukema JW, Macfarlane PW, Murphy MB, Stott DJ, Westendorp RG, Shepherd J, Ford I, Packard CJ; Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Study Group.

PLoS Med. 2009 Jun 23;6(6):e1000099. doi: 10.1371/journal.pmed.1000099. Epub 2009 Jun 23.

PMID:
19554082
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.

Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9362-7. doi: 10.1073/pnas.0903103106. Epub 2009 May 27.

PMID:
19474294
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Tocilizumab: a review of its use in the management of rheumatoid arthritis.

Oldfield V, Dhillon S, Plosker GL.

Drugs. 2009;69(5):609-32. doi: 10.2165/00003495-200969050-00007. Review.

PMID:
19368420
[PubMed - indexed for MEDLINE]
16.

Interpreting lipid levels in the context of high-grade inflammatory states with a focus on rheumatoid arthritis: a challenge to conventional cardiovascular risk actions.

Choy E, Sattar N.

Ann Rheum Dis. 2009 Apr;68(4):460-9. doi: 10.1136/ard.2008.101964. Review.

PMID:
19286905
[PubMed - indexed for MEDLINE]
17.

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.

Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, Li M, Derohannessian S, de Bakker PI, Bailey SD, Montpetit A, Edmondson AC, Taylor K, Gai X, Wang SS, Fornage M, Shaikh T, Groop L, Boehnke M, Hall AS, Hattersley AT, Frackelton E, Patterson N, Chiang CW, Kim CE, Fabsitz RR, Ouwehand W, Price AL, Munroe P, Caulfield M, Drake T, Boerwinkle E, Reich D, Whitehead AS, Cappola TP, Samani NJ, Lusis AJ, Schadt E, Wilson JG, Koenig W, McCarthy MI, Kathiresan S, Gabriel SB, Hakonarson H, Anand SS, Reilly M, Engert JC, Nickerson DA, Rader DJ, Hirschhorn JN, Fitzgerald GA.

PLoS One. 2008;3(10):e3583. doi: 10.1371/journal.pone.0003583. Epub 2008 Oct 31.

PMID:
18974833
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease-modifying antirheumatic drugs: the tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study.

Genovese MC, McKay JD, Nasonov EL, Mysler EF, da Silva NA, Alecock E, Woodworth T, Gomez-Reino JJ.

Arthritis Rheum. 2008 Oct;58(10):2968-80. doi: 10.1002/art.23940.

PMID:
18821691
[PubMed - indexed for MEDLINE]
Free Article
19.

Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease.

Nishimoto N, Terao K, Mima T, Nakahara H, Takagi N, Kakehi T.

Blood. 2008 Nov 15;112(10):3959-64. doi: 10.1182/blood-2008-05-155846. Epub 2008 Sep 10.

PMID:
18784373
[PubMed - indexed for MEDLINE]
Free Article
20.

Actemra poised to launch IL-6 inhibitors.

Melton L, Coombs A.

Nat Biotechnol. 2008 Sep;26(9):957-9. doi: 10.1038/nbt0908-957. No abstract available. Erratum in: Nat Biotechnol. 2008 Dec;26(12):1383.

PMID:
18779787
[PubMed - indexed for MEDLINE]
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