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Results: 1 to 20 of 37

1.

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator.

Shuda M, Kwun HJ, Feng H, Chang Y, Moore PS.

J Clin Invest. 2011 Sep;121(9):3623-34. doi: 10.1172/JCI46323. Epub 2011 Aug 15.

PMID:
21841310
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens.

Houben R, Shuda M, Weinkam R, Schrama D, Feng H, Chang Y, Moore PS, Becker JC.

J Virol. 2010 Jul;84(14):7064-72. doi: 10.1128/JVI.02400-09. Epub 2010 May 5.

PMID:
20444890
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Quantitation of human seroresponsiveness to Merkel cell polyomavirus.

Pastrana DV, Tolstov YL, Becker JC, Moore PS, Chang Y, Buck CB.

PLoS Pathog. 2009 Sep;5(9):e1000578. doi: 10.1371/journal.ppat.1000578. Epub 2009 Sep 11.

PMID:
19750217
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Targeting the phosphoinositide 3-kinase pathway in cancer.

Liu P, Cheng H, Roberts TM, Zhao JJ.

Nat Rev Drug Discov. 2009 Aug;8(8):627-44. doi: 10.1038/nrd2926. Review.

PMID:
19644473
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the PIK3CA gene.

Hurst CD, Zuiverloon TC, Hafner C, Zwarthoff EC, Knowles MA.

BMC Res Notes. 2009 Apr 29;2:66. doi: 10.1186/1756-0500-2-66.

PMID:
19402901
[PubMed]
Free PMC Article
6.

Phosphatidylinositol-3-kinase as a therapeutic target in melanoma.

Aziz SA, Davies M, Pick E, Zito C, Jilaveanu L, Camp RL, Rimm DL, Kluger Y, Kluger HM.

Clin Cancer Res. 2009 May 1;15(9):3029-36. doi: 10.1158/1078-0432.CCR-08-2768. Epub 2009 Apr 21.

PMID:
19383818
[PubMed - indexed for MEDLINE]
Free Article
7.

BI-69A11-mediated inhibition of AKT leads to effective regression of xenograft melanoma.

Gaitonde S, De SK, Tcherpakov M, Dewing A, Yuan H, Riel-Mehan M, Krajewski S, Robertson G, Pellecchia M, Ronai Z.

Pigment Cell Melanoma Res. 2009 Apr;22(2):187-95. doi: 10.1111/j.1755-148X.2009.00544.x. Epub 2009 Jan 17.

PMID:
19175524
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Merkel cell carcinoma.

Becker JC, Schrama D, Houben R.

Cell Mol Life Sci. 2009 Jan;66(1):1-8. doi: 10.1007/s00018-008-8483-6. Review.

PMID:
19023519
[PubMed - indexed for MEDLINE]
9.

Array-CGH reveals recurrent genomic changes in Merkel cell carcinoma including amplification of L-Myc.

Paulson KG, Lemos BD, Feng B, Jaimes N, Peñas PF, Bi X, Maher E, Cohen L, Leonard JH, Granter SR, Chin L, Nghiem P.

J Invest Dermatol. 2009 Jun;129(6):1547-55. doi: 10.1038/jid.2008.365. Epub 2008 Nov 20.

PMID:
19020549
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus.

Shuda M, Feng H, Kwun HJ, Rosen ST, Gjoerup O, Moore PS, Chang Y.

Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16272-7. doi: 10.1073/pnas.0806526105. Epub 2008 Sep 23.

PMID:
18812503
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

MC polyomavirus is frequently present in Merkel cell carcinoma of European patients.

Becker JC, Houben R, Ugurel S, Trefzer U, Pföhler C, Schrama D.

J Invest Dermatol. 2009 Jan;129(1):248-50. doi: 10.1038/jid.2008.198. Epub 2008 Jul 17. No abstract available.

PMID:
18633441
[PubMed - indexed for MEDLINE]
Free Article
12.

AKT1(E17K) in human solid tumours.

Bleeker FE, Felicioni L, Buttitta F, Lamba S, Cardone L, Rodolfo M, Scarpa A, Leenstra S, Frattini M, Barbareschi M, Grammastro MD, Sciarrotta MG, Zanon C, Marchetti A, Bardelli A.

Oncogene. 2008 Sep 18;27(42):5648-50. doi: 10.1038/onc.2008.170. Epub 2008 May 26.

PMID:
18504432
[PubMed - indexed for MEDLINE]
13.
14.

p14ARF hypermethylation is common but INK4a-ARF locus or p53 mutations are rare in Merkel cell carcinoma.

Lassacher A, Heitzer E, Kerl H, Wolf P.

J Invest Dermatol. 2008 Jul;128(7):1788-96. doi: 10.1038/sj.jid.5701256. Epub 2008 Jan 24.

PMID:
18219279
[PubMed - indexed for MEDLINE]
Free Article
15.

Clonal integration of a polyomavirus in human Merkel cell carcinoma.

Feng H, Shuda M, Chang Y, Moore PS.

Science. 2008 Feb 22;319(5866):1096-100. doi: 10.1126/science.1152586. Epub 2008 Jan 17.

PMID:
18202256
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Merkel cell carcinoma: more deaths but still no pathway to blame.

Lemos B, Nghiem P.

J Invest Dermatol. 2007 Sep;127(9):2100-3.

PMID:
17700621
[PubMed - indexed for MEDLINE]
Free Article
17.

Significance of the expression of phosphorylated-STAT3, -Akt, and -ERK1/2 in several tumors of the epidermis.

Lin N, Moroi Y, Uchi H, Fukiwake N, Dainichi T, Takeuchi S, Takahara M, Tu Y, Furue M, Urabe K.

J Dermatol Sci. 2007 Oct;48(1):71-3. Epub 2007 Aug 7. No abstract available.

PMID:
17686614
[PubMed - indexed for MEDLINE]
18.

Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern.

Hafner C, López-Knowles E, Luis NM, Toll A, Baselga E, Fernández-Casado A, Hernández S, Ribé A, Mentzel T, Stoehr R, Hofstaedter F, Landthaler M, Vogt T, Pujol RM, Hartmann A, Real FX.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13450-4. Epub 2007 Aug 2.

PMID:
17673550
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.

Carpten JD, Faber AL, Horn C, Donoho GP, Briggs SL, Robbins CM, Hostetter G, Boguslawski S, Moses TY, Savage S, Uhlik M, Lin A, Du J, Qian YW, Zeckner DJ, Tucker-Kellogg G, Touchman J, Patel K, Mousses S, Bittner M, Schevitz R, Lai MH, Blanchard KL, Thomas JE.

Nature. 2007 Jul 26;448(7152):439-44. Epub 2007 Jul 4.

PMID:
17611497
[PubMed - indexed for MEDLINE]
20.

Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skin.

Rittié L, Kansra S, Stoll SW, Li Y, Gudjonsson JE, Shao Y, Michael LE, Fisher GJ, Johnson TM, Elder JT.

Am J Pathol. 2007 Jun;170(6):2089-99.

PMID:
17525275
[PubMed - indexed for MEDLINE]
Free PMC Article
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