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Results: 1 to 20 of 60

1.

Bardoxolone methyl and kidney function in CKD with type 2 diabetes.

Pergola PE, Raskin P, Toto RD, Meyer CJ, Huff JW, Grossman EB, Krauth M, Ruiz S, Audhya P, Christ-Schmidt H, Wittes J, Warnock DG; BEAM Study Investigators.

N Engl J Med. 2011 Jul 28;365(4):327-36. doi: 10.1056/NEJMoa1105351. Epub 2011 Jun 24.

PMID:
21699484
[PubMed - indexed for MEDLINE]
Free Article
2.

Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD.

Pergola PE, Krauth M, Huff JW, Ferguson DA, Ruiz S, Meyer CJ, Warnock DG.

Am J Nephrol. 2011;33(5):469-76. doi: 10.1159/000327599. Epub 2011 Apr 21.

PMID:
21508635
[PubMed - indexed for MEDLINE]
Free Article
3.

Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis.

Neymotin A, Calingasan NY, Wille E, Naseri N, Petri S, Damiano M, Liby KT, Risingsong R, Sporn M, Beal MF, Kiaei M.

Free Radic Biol Med. 2011 Jul 1;51(1):88-96. doi: 10.1016/j.freeradbiomed.2011.03.027. Epub 2011 Mar 30.

PMID:
21457778
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation.

Gutcher I, Donkor MK, Ma Q, Rudensky AY, Flavell RA, Li MO.

Immunity. 2011 Mar 25;34(3):396-408. doi: 10.1016/j.immuni.2011.03.005.

PMID:
21435587
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Fumaric acid and its esters: an emerging treatment for multiple sclerosis with antioxidative mechanism of action.

Gold R, Linker RA, Stangel M.

Clin Immunol. 2012 Jan;142(1):44-8. doi: 10.1016/j.clim.2011.02.017. Epub 2011 Feb 26. Review.

PMID:
21414846
[PubMed - indexed for MEDLINE]
6.

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

Linker RA, Lee DH, Ryan S, van Dam AM, Conrad R, Bista P, Zeng W, Hronowsky X, Buko A, Chollate S, Ellrichmann G, Brück W, Dawson K, Goelz S, Wiese S, Scannevin RH, Lukashev M, Gold R.

Brain. 2011 Mar;134(Pt 3):678-92. doi: 10.1093/brain/awq386.

PMID:
21354971
[PubMed - indexed for MEDLINE]
Free Article
7.

Th17 cell, the new player of neuroinflammatory process in multiple sclerosis.

Jadidi-Niaragh F, Mirshafiey A.

Scand J Immunol. 2011 Jul;74(1):1-13. doi: 10.1111/j.1365-3083.2011.02536.x. Review.

PMID:
21338381
[PubMed - indexed for MEDLINE]
8.

Mechanisms of oxidative damage in multiple sclerosis and a cell therapy approach to treatment.

Witherick J, Wilkins A, Scolding N, Kemp K.

Autoimmune Dis. 2010 Dec 15;2011:164608. doi: 10.4061/2011/164608.

PMID:
21197107
[PubMed]
Free PMC Article
9.

Erythropoietin enhances endogenous haem oxygenase-1 and represses immune responses to ameliorate experimental autoimmune encephalomyelitis.

Chen SJ, Wang YL, Lo WT, Wu CC, Hsieh CW, Huang CF, Lan YH, Wang CC, Chang DM, Sytwu HK.

Clin Exp Immunol. 2010 Nov;162(2):210-23.

PMID:
21069936
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11beta-hydroxysteroid dehydrogenases in multiple sclerosis: implications for lesion pathogenesis.

Heidbrink C, Häusler SF, Buttmann M, Ossadnik M, Strik HM, Keller A, Buck D, Verbraak E, van Meurs M, Krockenberger M, Mehling M, Mittelbronn M, Laman JD, Wiendl H, Wischhusen J.

Brain Behav Immun. 2010 Aug;24(6):975-84. doi: 10.1016/j.bbi.2010.04.003. Epub 2010 Apr 10.

PMID:
20385225
[PubMed - indexed for MEDLINE]
11.

Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease.

Stack C, Ho D, Wille E, Calingasan NY, Williams C, Liby K, Sporn M, Dumont M, Beal MF.

Free Radic Biol Med. 2010 Jul 15;49(2):147-58. doi: 10.1016/j.freeradbiomed.2010.03.017. Epub 2010 Mar 23.

PMID:
20338236
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Hemin exerts multiple protective mechanisms and attenuates dextran sulfate sodium-induced colitis.

Zhong W, Xia Z, Hinrichs D, Rosenbaum JT, Wegmann KW, Meyrowitz J, Zhang Z.

J Pediatr Gastroenterol Nutr. 2010 Feb;50(2):132-9. doi: 10.1097/MPG.0b013e3181c61591.

PMID:
20081544
[PubMed - indexed for MEDLINE]
13.

The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis.

Johnson DA, Amirahmadi S, Ward C, Fabry Z, Johnson JA.

Toxicol Sci. 2010 Apr;114(2):237-46. doi: 10.1093/toxsci/kfp274. Epub 2009 Nov 12.

PMID:
19910389
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Beneficial actions of oleanolic acid in an experimental model of multiple sclerosis: a potential therapeutic role.

Martín R, Carvalho-Tavares J, Hernández M, Arnés M, Ruiz-Gutiérrez V, Nieto ML.

Biochem Pharmacol. 2010 Jan 15;79(2):198-208. doi: 10.1016/j.bcp.2009.08.002. Epub 2009 Aug 11.

PMID:
19679109
[PubMed - indexed for MEDLINE]
15.

Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK.

Jin W, Zhou XF, Yu J, Cheng X, Sun SC.

Blood. 2009 Jun 25;113(26):6603-10. doi: 10.1182/blood-2008-12-192914. Epub 2009 May 1.

PMID:
19411637
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease.

Dumont M, Wille E, Calingasan NY, Tampellini D, Williams C, Gouras GK, Liby K, Sporn M, Nathan C, Flint Beal M, Lin MT.

J Neurochem. 2009 Apr;109(2):502-12. doi: 10.1111/j.1471-4159.2009.05970.x. Epub 2009 Feb 7. Erratum in: J Neurochem. 2009 May;109(4):1192.. Nathan, Carl [added].

PMID:
19200343
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Decreased intrathecal synthesis of prostaglandin D2 synthase in the cerebrospinal fluid of patients with acute inflammatory demyelinating polyneuropathy.

Huang YC, Lyu RK, Tseng MY, Chang HS, Hsu WC, Kuo HC, Chu CC, Wu YR, Ro LS, Huang CC, Chen CM.

J Neuroimmunol. 2009 Jan 3;206(1-2):100-5. doi: 10.1016/j.jneuroim.2008.10.011. Epub 2008 Dec 2.

PMID:
19049845
[PubMed - indexed for MEDLINE]
18.

Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction.

Ogura H, Murakami M, Okuyama Y, Tsuruoka M, Kitabayashi C, Kanamoto M, Nishihara M, Iwakura Y, Hirano T.

Immunity. 2008 Oct 17;29(4):628-36. doi: 10.1016/j.immuni.2008.07.018. Epub 2008 Oct 9.

PMID:
18848474
[PubMed - indexed for MEDLINE]
Free Article
19.

The transcription factor Nrf2 is a therapeutic target against brain inflammation.

Innamorato NG, Rojo AI, García-Yagüe AJ, Yamamoto M, de Ceballos ML, Cuadrado A.

J Immunol. 2008 Jul 1;181(1):680-9.

PMID:
18566435
[PubMed - indexed for MEDLINE]
Free Article
20.

A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells.

Bayer AL, Lee JY, de la Barrera A, Surh CD, Malek TR.

J Immunol. 2008 Jul 1;181(1):225-34.

PMID:
18566388
[PubMed - indexed for MEDLINE]
Free PMC Article

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