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Results: 1 to 20 of 59

References for PMC Articles for PubMed (Select 22351767)


Nanoscale architecture of integrin-based cell adhesions.

Kanchanawong P, Shtengel G, Pasapera AM, Ramko EB, Davidson MW, Hess HF, Waterman CM.

Nature. 2010 Nov 25;468(7323):580-4. doi: 10.1038/nature09621.


The Structure of the talin head reveals a novel extended conformation of the FERM domain.

Elliott PR, Goult BT, Kopp PM, Bate N, Grossmann JG, Roberts GC, Critchley DR, Barsukov IL.

Structure. 2010 Oct 13;18(10):1289-99. doi: 10.1016/j.str.2010.07.011.


The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.

Kalli AC, Wegener KL, Goult BT, Anthis NJ, Campbell ID, Sansom MS.

Structure. 2010 Oct 13;18(10):1280-8. doi: 10.1016/j.str.2010.07.012.


Vinculin activates inside-out signaling of integrin αIIbβ3 in Chinese hamster ovary cells.

Ohmori T, Kashiwakura Y, Ishiwata A, Madoiwa S, Mimuro J, Honda S, Miyata T, Sakata Y.

Biochem Biophys Res Commun. 2010 Sep 24;400(3):323-8. doi: 10.1016/j.bbrc.2010.08.056. Epub 2010 Aug 20.


Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.

Kopp PM, Bate N, Hansen TM, Brindle NP, Praekelt U, Debrand E, Coleman S, Mazzeo D, Goult BT, Gingras AR, Pritchard CA, Critchley DR, Monkley SJ.

Eur J Cell Biol. 2010 Sep;89(9):661-73. doi: 10.1016/j.ejcb.2010.05.003.


Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.

Goult BT, Bouaouina M, Elliott PR, Bate N, Patel B, Gingras AR, Grossmann JG, Roberts GC, Calderwood DA, Critchley DR, Barsukov IL.

EMBO J. 2010 Mar 17;29(6):1069-80. doi: 10.1038/emboj.2010.4. Epub 2010 Feb 11.


Recreation of the terminal events in physiological integrin activation.

Ye F, Hu G, Taylor D, Ratnikov B, Bobkov AA, McLean MA, Sligar SG, Taylor KA, Ginsberg MH.

J Cell Biol. 2010 Jan 11;188(1):157-73. doi: 10.1083/jcb.200908045. Epub 2010 Jan 4.


The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.

Anthis NJ, Wegener KL, Ye F, Kim C, Goult BT, Lowe ED, Vakonakis I, Bate N, Critchley DR, Ginsberg MH, Campbell ID.

EMBO J. 2009 Nov 18;28(22):3623-32. doi: 10.1038/emboj.2009.287. Epub 2009 Oct 1.


Biochemical and structural properties of the integrin-associated cytoskeletal protein talin.

Critchley DR.

Annu Rev Biophys. 2009;38:235-54. doi: 10.1146/annurev.biophys.050708.133744. Review.


The structure of an interdomain complex that regulates talin activity.

Goult BT, Bate N, Anthis NJ, Wegener KL, Gingras AR, Patel B, Barsukov IL, Campbell ID, Roberts GC, Critchley DR.

J Biol Chem. 2009 May 29;284(22):15097-106. doi: 10.1074/jbc.M900078200. Epub 2009 Mar 18.


Stretching single talin rod molecules activates vinculin binding.

del Rio A, Perez-Jimenez R, Liu R, Roca-Cusachs P, Fernandez JM, Sheetz MP.

Science. 2009 Jan 30;323(5914):638-41. doi: 10.1126/science.1162912.


Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails.

Legate KR, Fässler R.

J Cell Sci. 2009 Jan 15;122(Pt 2):187-98. doi: 10.1242/jcs.041624. Review.


RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences.

Lee HS, Lim CJ, Puzon-McLaughlin W, Shattil SJ, Ginsberg MH.

J Biol Chem. 2009 Feb 20;284(8):5119-27. doi: 10.1074/jbc.M807117200. Epub 2008 Dec 19.


Structural basis for the autoinhibition of talin in regulating integrin activation.

Goksoy E, Ma YQ, Wang X, Kong X, Perera D, Plow EF, Qin J.

Mol Cell. 2008 Jul 11;31(1):124-33. doi: 10.1016/j.molcel.2008.06.011.


Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3.

Watanabe N, Bodin L, Pandey M, Krause M, Coughlin S, Boussiotis VA, Ginsberg MH, Shattil SJ.

J Cell Biol. 2008 Jun 30;181(7):1211-22. doi: 10.1083/jcb.200803094. Epub 2008 Jun 23.


The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins.

Bouaouina M, Lad Y, Calderwood DA.

J Biol Chem. 2008 Mar 7;283(10):6118-25. doi: 10.1074/jbc.M709527200. Epub 2007 Dec 28.


The structure of the C-terminal actin-binding domain of talin.

Gingras AR, Bate N, Goult BT, Hazelwood L, Canestrelli I, Grossmann JG, Liu H, Putz NS, Roberts GC, Volkmann N, Hanein D, Barsukov IL, Critchley DR.

EMBO J. 2008 Jan 23;27(2):458-69. Epub 2007 Dec 20.


Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo.

Nieswandt B, Moser M, Pleines I, Varga-Szabo D, Monkley S, Critchley D, Fässler R.

J Exp Med. 2007 Dec 24;204(13):3113-8. Epub 2007 Dec 17.


Talin is required for integrin-mediated platelet function in hemostasis and thrombosis.

Petrich BG, Marchese P, Ruggeri ZM, Spiess S, Weichert RA, Ye F, Tiedt R, Skoda RC, Monkley SJ, Critchley DR, Ginsberg MH.

J Exp Med. 2007 Dec 24;204(13):3103-11. Epub 2007 Dec 17.


Vinculin controls focal adhesion formation by direct interactions with talin and actin.

Humphries JD, Wang P, Streuli C, Geiger B, Humphries MJ, Ballestrem C.

J Cell Biol. 2007 Dec 3;179(5):1043-57.

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