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Items: 1 to 20 of 52


Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface.

Ismail AS, Severson KM, Vaishnava S, Behrendt CL, Yu X, Benjamin JL, Ruhn KA, Hou B, DeFranco AL, Yarovinsky F, Hooper LV.

Proc Natl Acad Sci U S A. 2011 May 24;108(21):8743-8. doi: 10.1073/pnas.1019574108. Epub 2011 May 9.


Interactions between the host innate immune system and microbes in inflammatory bowel disease.

Abraham C, Medzhitov R.

Gastroenterology. 2011 May;140(6):1729-37. doi: 10.1053/j.gastro.2011.02.012. Review.


Experimental inflammatory bowel disease: insights into the host-microbiota dialog.

Saleh M, Elson CO.

Immunity. 2011 Mar 25;34(3):293-302. doi: 10.1016/j.immuni.2011.03.008. Review.


Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response.

Hou B, Saudan P, Ott G, Wheeler ML, Ji M, Kuzmich L, Lee LM, Coffman RL, Bachmann MF, DeFranco AL.

Immunity. 2011 Mar 25;34(3):375-84. doi: 10.1016/j.immuni.2011.01.011. Epub 2011 Feb 25.


Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense.

Wei M, Shinkura R, Doi Y, Maruya M, Fagarasan S, Honjo T.

Nat Immunol. 2011 Mar;12(3):264-70. doi: 10.1038/ni.1991. Epub 2011 Jan 23.


Immunoglobulin responses at the mucosal interface.

Cerutti A, Chen K, Chorny A.

Annu Rev Immunol. 2011;29:273-93. doi: 10.1146/annurev-immunol-031210-101317. Review.


Has the microbiota played a critical role in the evolution of the adaptive immune system?

Lee YK, Mazmanian SK.

Science. 2010 Dec 24;330(6012):1768-73. doi: 10.1126/science.1195568. Review.


Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors.

Hou B, Benson A, Kuzmich L, DeFranco AL, Yarovinsky F.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):278-83. doi: 10.1073/pnas.1011549108. Epub 2010 Dec 20.


Innate immune mechanisms of colitis and colitis-associated colorectal cancer.

Saleh M, Trinchieri G.

Nat Rev Immunol. 2011 Jan;11(1):9-20. doi: 10.1038/nri2891. Epub 2010 Dec 10. Review.


MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands.

Brandl K, Sun L, Neppl C, Siggs OM, Le Gall SM, Tomisato W, Li X, Du X, Maennel DN, Blobel CP, Beutler B.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19967-72. doi: 10.1073/pnas.1014669107. Epub 2010 Nov 1.


An innately dangerous balancing act: intestinal homeostasis, inflammation, and colitis-associated cancer.

Asquith M, Powrie F.

J Exp Med. 2010 Aug 2;207(8):1573-7. doi: 10.1084/jem.20101330. Review.


MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18.

Salcedo R, Worschech A, Cardone M, Jones Y, Gyulai Z, Dai RM, Wang E, Ma W, Haines D, O'hUigin C, Marincola FM, Trinchieri G.

J Exp Med. 2010 Aug 2;207(8):1625-36. doi: 10.1084/jem.20100199. Epub 2010 Jul 12.


The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions.

Johansson ME, Larsson JM, Hansson GC.

Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4659-65. doi: 10.1073/pnas.1006451107. Epub 2010 Jun 25.


Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses.

Hapfelmeier S, Lawson MA, Slack E, Kirundi JK, Stoel M, Heikenwalder M, Cahenzli J, Velykoredko Y, Balmer ML, Endt K, Geuking MB, Curtiss R 3rd, McCoy KD, Macpherson AJ.

Science. 2010 Jun 25;328(5986):1705-9. doi: 10.1126/science.1188454.


Homeostasis and inflammation in the intestine.

Garrett WS, Gordon JI, Glimcher LH.

Cell. 2010 Mar 19;140(6):859-70. doi: 10.1016/j.cell.2010.01.023. Review.


Th17 and regulatory T cells in mediating and restraining inflammation.

Littman DR, Rudensky AY.

Cell. 2010 Mar 19;140(6):845-58. doi: 10.1016/j.cell.2010.02.021. Review.


The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.

Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD.

Immunity. 2010 Mar 26;32(3):379-91. doi: 10.1016/j.immuni.2010.03.003. Epub 2010 Mar 18.


Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases.

Dupaul-Chicoine J, Yeretssian G, Doiron K, Bergstrom KS, McIntire CR, LeBlanc PM, Meunier C, Turbide C, Gros P, Beauchemin N, Vallance BA, Saleh M.

Immunity. 2010 Mar 26;32(3):367-78. doi: 10.1016/j.immuni.2010.02.012. Epub 2010 Mar 11.


Intestinal bacteria and the regulation of immune cell homeostasis.

Hill DA, Artis D.

Annu Rev Immunol. 2010;28:623-67. doi: 10.1146/annurev-immunol-030409-101330. Review.


Adaptive immune regulation in the gut: T cell-dependent and T cell-independent IgA synthesis.

Fagarasan S, Kawamoto S, Kanagawa O, Suzuki K.

Annu Rev Immunol. 2010;28:243-73. doi: 10.1146/annurev-immunol-030409-101314. Review.

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