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RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer.

Flavin P, Redmond A, McBryan J, Cocchiglia S, Tibbitts P, Fahy-Browne P, Kay E, Treumann A, Perrem K, McIlroy M, Hill AD, Young LS.

FEBS Lett. 2011 Aug 4;585(15):2537-44. doi: 10.1016/j.febslet.2011.07.005. Epub 2011 Jul 13.


The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components.

Stirling PC, Bloom MS, Solanki-Patil T, Smith S, Sipahimalani P, Li Z, Kofoed M, Ben-Aroya S, Myung K, Hieter P.

PLoS Genet. 2011 Apr;7(4):e1002057. doi: 10.1371/journal.pgen.1002057. Epub 2011 Apr 28.


Mediator influences telomeric silencing and cellular life span.

Zhu X, Liu B, Carlsten JO, Beve J, Nyström T, Myers LC, Gustafsson CM.

Mol Cell Biol. 2011 Jun;31(12):2413-21. doi: 10.1128/MCB.05242-11. Epub 2011 Apr 11.


CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.

Horejsí Z, Takai H, Adelman CA, Collis SJ, Flynn H, Maslen S, Skehel JM, de Lange T, Boulton SJ.

Mol Cell. 2010 Sep 24;39(6):839-50. doi: 10.1016/j.molcel.2010.08.037.


A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.

Hurov KE, Cotta-Ramusino C, Elledge SJ.

Genes Dev. 2010 Sep 1;24(17):1939-50. doi: 10.1101/gad.1934210.


Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.

Takai H, Xie Y, de Lange T, Pavletich NP.

Genes Dev. 2010 Sep 15;24(18):2019-30. doi: 10.1101/gad.1956410. Epub 2010 Aug 27.


Reptin is required for the transcription of telomerase reverse transcriptase and over-expressed in gastric cancer.

Li W, Zeng J, Li Q, Zhao L, Liu T, Björkholm M, Jia J, Xu D.

Mol Cancer. 2010 May 30;9:132. doi: 10.1186/1476-4598-9-132.


AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay.

Izumi N, Yamashita A, Iwamatsu A, Kurata R, Nakamura H, Saari B, Hirano H, Anderson P, Ohno S.

Sci Signal. 2010 Apr 6;3(116):ra27. doi: 10.1126/scisignal.2000468.


Rvb1-Rvb2: essential ATP-dependent helicases for critical complexes.

Huen J, Kakihara Y, Ugwu F, Cheung KL, Ortega J, Houry WA.

Biochem Cell Biol. 2010 Feb;88(1):29-40. doi: 10.1139/o09-122. Review.


The genetic landscape of a cell.

Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, Alizadeh S, Bahr S, Brost RL, Chen Y, Cokol M, Deshpande R, Li Z, Lin ZY, Liang W, Marback M, Paw J, San Luis BJ, Shuteriqi E, Tong AH, van Dyk N, Wallace IM, Whitney JA, Weirauch MT, Zhong G, Zhu H, Houry WA, Brudno M, Ragibizadeh S, Papp B, Pál C, Roth FP, Giaever G, Nislow C, Troyanskaya OG, Bussey H, Bader GD, Gingras AC, Morris QD, Kim PM, Kaiser CA, Myers CL, Andrews BJ, Boone C.

Science. 2010 Jan 22;327(5964):425-31. doi: 10.1126/science.1180823.


How telomeres solve the end-protection problem.

de Lange T.

Science. 2009 Nov 13;326(5955):948-52. doi: 10.1126/science.1170633.


RVB1/RVB2: running rings around molecular biology.

Jha S, Dutta A.

Mol Cell. 2009 Jun 12;34(5):521-33. doi: 10.1016/j.molcel.2009.05.016. Review.


Functional dissection of Caenorhabditis elegans CLK-2/TEL2 cell cycle defects during embryogenesis and germline development.

Moser SC, von Elsner S, Büssing I, Alpi A, Schnabel R, Gartner A.

PLoS Genet. 2009 Apr;5(4):e1000451. doi: 10.1371/journal.pgen.1000451. Epub 2009 Apr 10. Erratum in: PLoS Genet. 2011 May;7(5). doi:10.1371/annotation/5c0706a8-a9c2-452a-b061-a7c60dbc0499.


Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.

Shevchenko A, Roguev A, Schaft D, Buchanan L, Habermann B, Sakalar C, Thomas H, Krogan NJ, Shevchenko A, Stewart AF.

Genome Biol. 2008;9(11):R167. doi: 10.1186/gb-2008-9-11-r167. Epub 2008 Nov 28.


Mec1 function in the DNA damage response does not require its interaction with Tel2.

Anderson CM, Blackburn EH.

Cell Cycle. 2008 Dec;7(23):3695-8. Epub 2008 Dec 7.


Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex.

Bourbon HM.

Nucleic Acids Res. 2008 Jul;36(12):3993-4008. doi: 10.1093/nar/gkn349. Epub 2008 May 31.


ATM-like kinases and regulation of telomerase: lessons from yeast and mammals.

Sabourin M, Zakian VA.

Trends Cell Biol. 2008 Jul;18(7):337-46. doi: 10.1016/j.tcb.2008.04.004. Epub 2008 May 22. Review.


Cell signaling. Tel2 finally tells one story.

Chang M, Lingner J.

Science. 2008 Apr 4;320(5872):60-1. doi: 10.1126/science.1155132. No abstract available.


Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break.

Anderson CM, Korkin D, Smith DL, Makovets S, Seidel JJ, Sali A, Blackburn EH.

Genes Dev. 2008 Apr 1;22(7):854-9. doi: 10.1101/gad.1646208. Epub 2008 Mar 11.


The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery.

Boulon S, Marmier-Gourrier N, Pradet-Balade B, Wurth L, Verheggen C, Jády BE, Rothé B, Pescia C, Robert MC, Kiss T, Bardoni B, Krol A, Branlant C, Allmang C, Bertrand E, Charpentier B.

J Cell Biol. 2008 Feb 11;180(3):579-95. doi: 10.1083/jcb.200708110.

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