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Results: 1 to 20 of 120

1.

Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia.

Burnett AK, Russell NH, Hills RK, Kell J, Freeman S, Kjeldsen L, Hunter AE, Yin J, Craddock CF, Dufva IH, Wheatley K, Milligan D.

J Clin Oncol. 2012 Nov 10;30(32):3924-31. doi: 10.1200/JCO.2012.42.2964. Epub 2012 Jul 30.

PMID:
22851554
[PubMed - indexed for MEDLINE]
2.

Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study.

Castaigne S, Pautas C, Terré C, Raffoux E, Bordessoule D, Bastie JN, Legrand O, Thomas X, Turlure P, Reman O, de Revel T, Gastaud L, de Gunzburg N, Contentin N, Henry E, Marolleau JP, Aljijakli A, Rousselot P, Fenaux P, Preudhomme C, Chevret S, Dombret H; Acute Leukemia French Association.

Lancet. 2012 Apr 21;379(9825):1508-16. doi: 10.1016/S0140-6736(12)60485-1. Epub 2012 Apr 5.

PMID:
22482940
[PubMed - indexed for MEDLINE]
3.

Correlation of CD33 expression level with disease characteristics and response to gemtuzumab ozogamicin containing chemotherapy in childhood AML.

Pollard JA, Alonzo TA, Loken M, Gerbing RB, Ho PA, Bernstein ID, Raimondi SC, Hirsch B, Franklin J, Walter RB, Gamis A, Meshinchi S.

Blood. 2012 Apr 19;119(16):3705-11. doi: 10.1182/blood-2011-12-398370. Epub 2012 Feb 29.

PMID:
22378848
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications.

Hou HA, Kuo YY, Liu CY, Chou WC, Lee MC, Chen CY, Lin LI, Tseng MH, Huang CF, Chiang YC, Lee FY, Liu MC, Liu CW, Tang JL, Yao M, Huang SY, Ko BS, Hsu SC, Wu SJ, Tsay W, Chen YC, Tien HF.

Blood. 2012 Jan 12;119(2):559-68. doi: 10.1182/blood-2011-07-369934. Epub 2011 Nov 10.

PMID:
22077061
[PubMed - indexed for MEDLINE]
Free Article
5.

Fractionated doses of gemtuzumab ozogamicin with escalated doses of daunorubicin and cytarabine as first acute myeloid leukemia salvage in patients aged 50-70-year old: a phase 1/2 study of the acute leukemia French association.

Farhat H, Reman O, Raffoux E, Berthon C, Pautas C, Kammoun L, Chantepie S, Gardin C, Rousselot P, Chevret S, Dombret H, Castaigne S.

Am J Hematol. 2012 Jan;87(1):62-5. doi: 10.1002/ajh.22201. Epub 2011 Nov 10.

PMID:
22072535
[PubMed - indexed for MEDLINE]
6.

Targeted drug delivery by gemtuzumab ozogamicin: mechanism-based mathematical model for treatment strategy improvement and therapy individualization.

Jager E, van der Velden VH, te Marvelde JG, Walter RB, Agur Z, Vainstein V.

PLoS One. 2011;6(9):e24265. doi: 10.1371/journal.pone.0024265. Epub 2011 Sep 7.

PMID:
21915304
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Stem cell gene expression programs influence clinical outcome in human leukemia.

Eppert K, Takenaka K, Lechman ER, Waldron L, Nilsson B, van Galen P, Metzeler KH, Poeppl A, Ling V, Beyene J, Canty AJ, Danska JS, Bohlander SK, Buske C, Minden MD, Golub TR, Jurisica I, Ebert BL, Dick JE.

Nat Med. 2011 Aug 28;17(9):1086-93. doi: 10.1038/nm.2415.

PMID:
21873988
[PubMed - indexed for MEDLINE]
8.

Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice.

Vassiliou GS, Cooper JL, Rad R, Li J, Rice S, Uren A, Rad L, Ellis P, Andrews R, Banerjee R, Grove C, Wang W, Liu P, Wright P, Arends M, Bradley A.

Nat Genet. 2011 May;43(5):470-5. doi: 10.1038/ng.796. Epub 2011 Mar 27.

PMID:
21441929
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia.

Goardon N, Marchi E, Atzberger A, Quek L, Schuh A, Soneji S, Woll P, Mead A, Alford KA, Rout R, Chaudhury S, Gilkes A, Knapper S, Beldjord K, Begum S, Rose S, Geddes N, Griffiths M, Standen G, Sternberg A, Cavenagh J, Hunter H, Bowen D, Killick S, Robinson L, Price A, Macintyre E, Virgo P, Burnett A, Craddock C, Enver T, Jacobsen SE, Porcher C, Vyas P.

Cancer Cell. 2011 Jan 18;19(1):138-52. doi: 10.1016/j.ccr.2010.12.012.

PMID:
21251617
[PubMed - indexed for MEDLINE]
Free Article
10.

Identification of patients with acute myeloblastic leukemia who benefit from the addition of gemtuzumab ozogamicin: results of the MRC AML15 trial.

Burnett AK, Hills RK, Milligan D, Kjeldsen L, Kell J, Russell NH, Yin JA, Hunter A, Goldstone AH, Wheatley K.

J Clin Oncol. 2011 Feb 1;29(4):369-77. doi: 10.1200/JCO.2010.31.4310. Epub 2010 Dec 20.

PMID:
21172891
[PubMed - indexed for MEDLINE]
11.

Gemtuzumab ozogamicin for the treatment of acute promyelocytic leukemia: mechanisms of action and resistance, safety and efficacy.

Breccia M, Lo-Coco F.

Expert Opin Biol Ther. 2011 Feb;11(2):225-34. doi: 10.1517/14712598.2011.543895. Epub 2010 Dec 11. Review.

PMID:
21142804
[PubMed - indexed for MEDLINE]
12.

Monoclonal antibody therapy directed against human acute myeloid leukemia stem cells.

Majeti R.

Oncogene. 2011 Mar 3;30(9):1009-19. doi: 10.1038/onc.2010.511. Epub 2010 Nov 15. Review.

PMID:
21076471
[PubMed - indexed for MEDLINE]
13.

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

Falini B, Martelli MP, Bolli N, Sportoletti P, Liso A, Tiacci E, Haferlach T.

Blood. 2011 Jan 27;117(4):1109-20. doi: 10.1182/blood-2010-08-299990. Epub 2010 Oct 28. Review.

PMID:
21030560
[PubMed - indexed for MEDLINE]
Free Article
14.

High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine.

Bachas C, Schuurhuis GJ, Hollink IH, Kwidama ZJ, Goemans BF, Zwaan CM, van den Heuvel-Eibrink MM, de Bont ES, Reinhardt D, Creutzig U, de Haas V, Assaraf YG, Kaspers GJ, Cloos J.

Blood. 2010 Oct 14;116(15):2752-8. doi: 10.1182/blood-2010-03-276519. Epub 2010 Jun 30.

PMID:
20592250
[PubMed - indexed for MEDLINE]
Free Article
15.

Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.

Taussig DC, Vargaftig J, Miraki-Moud F, Griessinger E, Sharrock K, Luke T, Lillington D, Oakervee H, Cavenagh J, Agrawal SG, Lister TA, Gribben JG, Bonnet D.

Blood. 2010 Mar 11;115(10):1976-84. doi: 10.1182/blood-2009-02-206565. Epub 2010 Jan 6.

PMID:
20053758
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Leukemia stem cells.

Lane SW, Gilliland DG.

Semin Cancer Biol. 2010 Apr;20(2):71-6. doi: 10.1016/j.semcancer.2009.12.001. Epub 2009 Dec 22. Review.

PMID:
20026405
[PubMed - indexed for MEDLINE]
17.

A family harboring a germ-line N-terminal C/EBPalpha mutation and development of acute myeloid leukemia with an additional somatic C-terminal C/EBPalpha mutation.

Nanri T, Uike N, Kawakita T, Iwanaga E, Mitsuya H, Asou N.

Genes Chromosomes Cancer. 2010 Mar;49(3):237-41. doi: 10.1002/gcc.20734.

PMID:
19953636
[PubMed - indexed for MEDLINE]
18.

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.

Guibal FC, Alberich-Jorda M, Hirai H, Ebralidze A, Levantini E, Di Ruscio A, Zhang P, Santana-Lemos BA, Neuberg D, Wagers AJ, Rego EM, Tenen DG.

Blood. 2009 Dec 24;114(27):5415-25. doi: 10.1182/blood-2008-10-182071. Epub 2009 Oct 1.

PMID:
19797526
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Analysis of factors that affect in vitro chemosensitivity of leukaemic stem and progenitor cells to gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukaemia.

Jawad M, Seedhouse C, Mony U, Grundy M, Russell NH, Pallis M.

Leukemia. 2010 Jan;24(1):74-80. doi: 10.1038/leu.2009.199. Epub 2009 Sep 24.

PMID:
19776761
[PubMed - indexed for MEDLINE]
20.

A robust xenotransplantation model for acute myeloid leukemia.

Sanchez PV, Perry RL, Sarry JE, Perl AE, Murphy K, Swider CR, Bagg A, Choi JK, Biegel JA, Danet-Desnoyers G, Carroll M.

Leukemia. 2009 Nov;23(11):2109-17. doi: 10.1038/leu.2009.143. Epub 2009 Jul 23.

PMID:
19626050
[PubMed - indexed for MEDLINE]
Free PMC Article

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