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Results: 1 to 20 of 29

1.

Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo.

Yamaguchi T, Kakefuda R, Tajima N, Sowa Y, Sakai T.

Int J Oncol. 2011 Jul;39(1):23-31. doi: 10.3892/ijo.2011.1015. Epub 2011 Apr 26.

PMID:
21523318
[PubMed - indexed for MEDLINE]
2.

DICKKOPF-4 activates the noncanonical c-Jun-NH2 kinase signaling pathway while inhibiting the Wnt-canonical pathway in human renal cell carcinoma.

Hirata H, Hinoda Y, Majid S, Chen Y, Zaman MS, Ueno K, Nakajima K, Tabatabai ZL, Ishii N, Dahiya R.

Cancer. 2011 Apr 15;117(8):1649-60. doi: 10.1002/cncr.25666. Epub 2010 Nov 8.

PMID:
21472712
[PubMed - indexed for MEDLINE]
Free Article
3.

Targeted-therapy in advanced renal cell carcinoma.

Pirrotta MT, Bernardeschi P, Fiorentini G.

Curr Med Chem. 2011;18(11):1651-7. Review.

PMID:
21428882
[PubMed - indexed for MEDLINE]
4.

Down-regulation of mir-424 contributes to the abnormal angiogenesis via MEK1 and cyclin E1 in senile hemangioma: its implications to therapy.

Nakashima T, Jinnin M, Etoh T, Fukushima S, Masuguchi S, Maruo K, Inoue Y, Ishihara T, Ihn H.

PLoS One. 2010 Dec 14;5(12):e14334. doi: 10.1371/journal.pone.0014334.

PMID:
21179471
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery.

Eulitt PJ, Park MA, Hossein H, Cruikshanks N, Yang C, Dmitriev IP, Yacoub A, Curiel DT, Fisher PB, Dent P.

Cancer Biol Ther. 2010 Dec 15;10(12):1290-305. Epub 2010 Dec 15.

PMID:
20948318
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

MicroRNA-34a inhibits cell proliferation by repressing mitogen-activated protein kinase kinase 1 during megakaryocytic differentiation of K562 cells.

Ichimura A, Ruike Y, Terasawa K, Shimizu K, Tsujimoto G.

Mol Pharmacol. 2010 Jun;77(6):1016-24. doi: 10.1124/mol.109.063321. Epub 2010 Mar 18.

PMID:
20299489
[PubMed - indexed for MEDLINE]
Free Article
7.

MicroRNA control of signal transduction.

Inui M, Martello G, Piccolo S.

Nat Rev Mol Cell Biol. 2010 Apr;11(4):252-63. doi: 10.1038/nrm2868. Epub 2010 Mar 10. Review.

PMID:
20216554
[PubMed - indexed for MEDLINE]
8.

Molecular diagnosis and therapy of kidney cancer.

Linehan WM, Bratslavsky G, Pinto PA, Schmidt LS, Neckers L, Bottaro DP, Srinivasan R.

Annu Rev Med. 2010;61:329-43. doi: 10.1146/annurev.med.042808.171650. Review.

PMID:
20059341
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

MicroRNAs as potential cancer therapeutics.

Trang P, Weidhaas JB, Slack FJ.

Oncogene. 2008 Dec;27 Suppl 2:S52-7. doi: 10.1038/onc.2009.353. Review.

PMID:
19956180
[PubMed - indexed for MEDLINE]
10.

miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion.

Xia H, Ng SS, Jiang S, Cheung WK, Sze J, Bian XW, Kung HF, Lin MC.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):535-41. doi: 10.1016/j.bbrc.2009.11.093. Epub 2009 Nov 24.

PMID:
19931509
[PubMed - indexed for MEDLINE]
11.

Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway.

Saydam O, Shen Y, W├╝rdinger T, Senol O, Boke E, James MF, Tannous BA, Stemmer-Rachamimov AO, Yi M, Stephens RM, Fraefel C, Gusella JF, Krichevsky AM, Breakefield XO.

Mol Cell Biol. 2009 Nov;29(21):5923-40. doi: 10.1128/MCB.00332-09. Epub 2009 Aug 24.

PMID:
19703993
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Expression of multidrug resistance markers ABCB1 (MDR-1/P-gp) and ABCC1 (MRP-1) in renal cell carcinoma.

Walsh N, Larkin A, Kennedy S, Connolly L, Ballot J, Ooi W, Gullo G, Crown J, Clynes M, O'Driscoll L.

BMC Urol. 2009 Jun 24;9:6. doi: 10.1186/1471-2490-9-6.

PMID:
19552816
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Expression of cortactin and survivin in renal cell carcinoma associated with tumor aggressiveness.

Wang GC, Hsieh PS, Hsu HH, Sun GH, Nieh S, Yu CP, Jin JS.

World J Urol. 2009 Aug;27(4):557-63. doi: 10.1007/s00345-009-0376-2. Epub 2009 Feb 15.

PMID:
19219613
[PubMed - indexed for MEDLINE]
14.

VHL loss of function and its impact on oncogenic signaling networks in clear cell renal cell carcinoma.

Linehan WM, Rubin JS, Bottaro DP.

Int J Biochem Cell Biol. 2009 Apr;41(4):753-6. doi: 10.1016/j.biocel.2008.09.024. Epub 2008 Oct 2. Review.

PMID:
18950731
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Predicting disease progression after nephrectomy for localized renal cell carcinoma: the utility of prognostic models and molecular biomarkers.

Crispen PL, Boorjian SA, Lohse CM, Leibovich BC, Kwon ED.

Cancer. 2008 Aug 1;113(3):450-60. doi: 10.1002/cncr.23566. Review.

PMID:
18523999
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

miRDB: a microRNA target prediction and functional annotation database with a wiki interface.

Wang X.

RNA. 2008 Jun;14(6):1012-7. doi: 10.1261/rna.965408. Epub 2008 Apr 21.

PMID:
18426918
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Cancer statistics, 2008.

Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ.

CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96. doi: 10.3322/CA.2007.0010. Epub 2008 Feb 20.

PMID:
18287387
[PubMed - indexed for MEDLINE]
Free Article
18.

Upstream signaling inhibition enhances rapamycin effect on growth of kidney cancer cells.

Costa LJ, Gemmill RM, Drabkin HA.

Urology. 2007 Mar;69(3):596-602.

PMID:
17382186
[PubMed - indexed for MEDLINE]
19.

Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics.

Linehan WM, Pinto PA, Srinivasan R, Merino M, Choyke P, Choyke L, Coleman J, Toro J, Glenn G, Vocke C, Zbar B, Schmidt LS, Bottaro D, Neckers L.

Clin Cancer Res. 2007 Jan 15;13(2 Pt 2):671s-679s. Review.

PMID:
17255292
[PubMed - indexed for MEDLINE]
Free Article
20.

Mining the Wnt pathway for cancer therapeutics.

Barker N, Clevers H.

Nat Rev Drug Discov. 2006 Dec;5(12):997-1014. Review. Erratum in: Nat Rev Drug Discov. 2007 Mar;6(3):249.

PMID:
17139285
[PubMed - indexed for MEDLINE]
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