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Items: 1 to 20 of 152

1.

Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63.

Contreras I, Gómez MA, Nguyen O, Shio MT, McMaster RW, Olivier M.

PLoS Pathog. 2010 Oct 14;6(10):e1001148. doi: 10.1371/journal.ppat.1001148.

2.

Modulation of the arginase pathway in the context of microbial pathogenesis: a metabolic enzyme moonlighting as an immune modulator.

Das P, Lahiri A, Lahiri A, Chakravortty D.

PLoS Pathog. 2010 Jun 17;6(6):e1000899. doi: 10.1371/journal.ppat.1000899. Review.

3.

Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases.

Gomez MA, Contreras I, Hallé M, Tremblay ML, McMaster RW, Olivier M.

Sci Signal. 2009 Sep 29;2(90):ra58. doi: 10.1126/scisignal.2000213.

4.

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.

Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M.

PLoS Pathog. 2009 Aug;5(8):e1000559. doi: 10.1371/journal.ppat.1000559. Epub 2009 Aug 21. Erratum in: PLoS Pathog. 2009 Sep;5(9). doi: 10.1371/annotation/abca067d-b82b-4de6-93c5-0fcc38e3df05. Tiemi Shio, Marina [corrected to Shio, Marina Tiemi].

5.

Transcriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes.

Osorio y Fortéa J, de La Llave E, Regnault B, Coppée JY, Milon G, Lang T, Prina E.

BMC Genomics. 2009 Mar 20;10:119. doi: 10.1186/1471-2164-10-119.

6.

Protein kinase C isoforms: Multi-functional regulators of cell life and death.

Reyland ME.

Front Biosci (Landmark Ed). 2009 Jan 1;14:2386-99. Review.

PMID:
19273207
7.

Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motif.

Abu-Dayyeh I, Shio MT, Sato S, Akira S, Cousineau B, Olivier M.

PLoS Negl Trop Dis. 2008;2(12):e305. doi: 10.1371/journal.pntd.0000305. Epub 2008 Dec 23.

8.

The Leishmania surface protease GP63 cleaves multiple intracellular proteins and actively participates in p38 mitogen-activated protein kinase inactivation.

Hallé M, Gomez MA, Stuible M, Shimizu H, McMaster WR, Olivier M, Tremblay ML.

J Biol Chem. 2009 Mar 13;284(11):6893-908. doi: 10.1074/jbc.M805861200. Epub 2008 Dec 8.

9.

Regulation of macrophage nitric oxide production by the protein tyrosine phosphatase Src homology 2 domain phosphotyrosine phosphatase 1 (SHP-1).

Blanchette J, Abu-Dayyeh I, Hassani K, Whitcombe L, Olivier M.

Immunology. 2009 May;127(1):123-33. doi: 10.1111/j.1365-2567.2008.02929.x.

10.

A novel form of NF-kappaB is induced by Leishmania infection: involvement in macrophage gene expression.

Gregory DJ, Godbout M, Contreras I, Forget G, Olivier M.

Eur J Immunol. 2008 Apr;38(4):1071-81. doi: 10.1002/eji.200737586.

11.

Interleukin-12: biological properties and clinical application.

Del Vecchio M, Bajetta E, Canova S, Lotze MT, Wesa A, Parmiani G, Anichini A.

Clin Cancer Res. 2007 Aug 15;13(16):4677-85. Review.

12.

Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii.

Debierre-Grockiego F, Campos MA, Azzouz N, Schmidt J, Bieker U, Resende MG, Mansur DS, Weingart R, Schmidt RR, Golenbock DT, Gazzinelli RT, Schwarz RT.

J Immunol. 2007 Jul 15;179(2):1129-37.

13.

Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide.

Mukbel RM, Patten C Jr, Gibson K, Ghosh M, Petersen C, Jones DE.

Am J Trop Med Hyg. 2007 Apr;76(4):669-75.

14.

Nonreceptor protein-tyrosine phosphatases in immune cell signaling.

Pao LI, Badour K, Siminovitch KA, Neel BG.

Annu Rev Immunol. 2007;25:473-523. Review.

PMID:
17291189
15.

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

Parroche P, Lauw FN, Goutagny N, Latz E, Monks BG, Visintin A, Halmen KA, Lamphier M, Olivier M, Bartholomeu DC, Gazzinelli RT, Golenbock DT.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1919-24. Epub 2007 Jan 29.

16.

Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism.

Gazzinelli RT, Denkers EY.

Nat Rev Immunol. 2006 Dec;6(12):895-906. Epub 2006 Nov 17. Review.

PMID:
17110955
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19.

Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection.

Bafica A, Santiago HC, Goldszmid R, Ropert C, Gazzinelli RT, Sher A.

J Immunol. 2006 Sep 15;177(6):3515-9.

20.
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