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Results: 1 to 20 of 38

References for PMC Articles for PubMed (Select 22120494)


Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury.

Mukhopadhyay P, Horváth B, Kechrid M, Tanchian G, Rajesh M, Naura AS, Boulares AH, Pacher P.

Free Radic Biol Med. 2011 Nov 1;51(9):1774-88. doi: 10.1016/j.freeradbiomed.2011.08.006. Epub 2011 Aug 17.


Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer.

Pabla N, Dong G, Jiang M, Huang S, Kumar MV, Messing RO, Dong Z.

J Clin Invest. 2011 Jul;121(7):2709-22. doi: 10.1172/JCI45586.


Mitochondria-targeted peptide accelerates ATP recovery and reduces ischemic kidney injury.

Szeto HH, Liu S, Soong Y, Wu D, Darrah SF, Cheng FY, Zhao Z, Ganger M, Tow CY, Seshan SV.

J Am Soc Nephrol. 2011 Jun;22(6):1041-52. doi: 10.1681/ASN.2010080808. Epub 2011 May 5.


Mitochondria-targeted small molecule therapeutics and probes.

Smith RA, Hartley RC, Murphy MP.

Antioxid Redox Signal. 2011 Dec 15;15(12):3021-38. doi: 10.1089/ars.2011.3969. Epub 2011 Jun 6. Review.


Mitochondria-targeted antioxidants as therapies.

Smith RA, Murphy MP.

Discov Med. 2011 Feb;11(57):106-14. Review.


Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury.

Mukhopadhyay P, Horváth B, Rajesh M, Matsumoto S, Saito K, Bátkai S, Patel V, Tanchian G, Gao RY, Cravatt BF, Haskó G, Pacher P.

Free Radic Biol Med. 2011 Jan 1;50(1):179-95. doi: 10.1016/j.freeradbiomed.2010.11.002. Epub 2010 Nov 9.


The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone.

Rao VA, Klein SR, Bonar SJ, Zielonka J, Mizuno N, Dickey JS, Keller PW, Joseph J, Kalyanaraman B, Shacter E.

J Biol Chem. 2010 Nov 5;285(45):34447-59. doi: 10.1074/jbc.M110.133579. Epub 2010 Aug 30.


Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.

Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, Kalyanaraman B, Mutlu GM, Budinger GR, Chandel NS.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8788-93. doi: 10.1073/pnas.1003428107. Epub 2010 Apr 26.


Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy.

Mukhopadhyay P, Rajesh M, Pan H, Patel V, Mukhopadhyay B, Bátkai S, Gao B, Haskó G, Pacher P.

Free Radic Biol Med. 2010 Feb 1;48(3):457-67. doi: 10.1016/j.freeradbiomed.2009.11.022. Epub 2009 Dec 4.


Transgenic expression of proximal tubule peroxisome proliferator-activated receptor-alpha in mice confers protection during acute kidney injury.

Li S, Nagothu KK, Desai V, Lee T, Branham W, Moland C, Megyesi JK, Crew MD, Portilla D.

Kidney Int. 2009 Nov;76(10):1049-62. doi: 10.1038/ki.2009.330. Epub 2009 Aug 26.


Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models.

Brooks C, Wei Q, Cho SG, Dong Z.

J Clin Invest. 2009 May;119(5):1275-85. doi: 10.1172/JCI37829. Epub 2009 Apr 6.


Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.

Cassina P, Cassina A, Pehar M, Castellanos R, Gandelman M, de León A, Robinson KM, Mason RP, Beckman JS, Barbeito L, Radi R.

J Neurosci. 2008 Apr 16;28(16):4115-22. doi: 10.1523/JNEUROSCI.5308-07.2008.


Cisplatin nephrotoxicity: mechanisms and renoprotective strategies.

Pabla N, Dong Z.

Kidney Int. 2008 May;73(9):994-1007. doi: 10.1038/ Epub 2008 Feb 13. Review.


TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity.

Zhang B, Ramesh G, Uematsu S, Akira S, Reeves WB.

J Am Soc Nephrol. 2008 May;19(5):923-32. doi: 10.1681/ASN.2007090982. Epub 2008 Feb 6.


Peroxynitrite: biochemistry, pathophysiology and development of therapeutics.

Szabó C, Ischiropoulos H, Radi R.

Nat Rev Drug Discov. 2007 Aug;6(8):662-80. Review.


Clonogenic assay of cells in vitro.

Franken NA, Rodermond HM, Stap J, Haveman J, van Bree C.

Nat Protoc. 2006;1(5):2315-9.


Cisplatin-induced nephrotoxicity is mediated by tumor necrosis factor-alpha produced by renal parenchymal cells.

Zhang B, Ramesh G, Norbury CC, Reeves WB.

Kidney Int. 2007 Jul;72(1):37-44. Epub 2007 Mar 28.


Nitric oxide and peroxynitrite in health and disease.

Pacher P, Beckman JS, Liaudet L.

Physiol Rev. 2007 Jan;87(1):315-424. Review.


Bid deficiency ameliorates ischemic renal failure and delays animal death in C57BL/6 mice.

Wei Q, Yin XM, Wang MH, Dong Z.

Am J Physiol Renal Physiol. 2006 Jan;290(1):F35-42. Epub 2005 Aug 16.


Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide.

Dhanasekaran A, Kotamraju S, Karunakaran C, Kalivendi SV, Thomas S, Joseph J, Kalyanaraman B.

Free Radic Biol Med. 2005 Sep 1;39(5):567-83.

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