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Items: 10

1.

Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs.

Maiques-Diaz A, Chou FS, Wunderlich M, Gómez-López G, Jacinto FV, Rodriguez-Perales S, Larrayoz MJ, Calasanz MJ, Mulloy JC, Cigudosa JC, Alvarez S.

Leukemia. 2012 Jun;26(6):1329-37. doi: 10.1038/leu.2011.376. Epub 2012 Jan 13.

PMID:
22289984
2.

Molecular pathogenesis of core binding factor leukemia: current knowledge and future prospects.

Goyama S, Mulloy JC.

Int J Hematol. 2011 Aug;94(2):126-33. doi: 10.1007/s12185-011-0858-z. Epub 2011 May 3. Review.

PMID:
21537931
3.

Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiency.

Jalagadugula G, Mao G, Kaur G, Goldfinger LE, Dhanasekaran DN, Rao AK.

Blood. 2010 Dec 23;116(26):6037-45. doi: 10.1182/blood-2010-06-289850. Epub 2010 Sep 27.

4.

Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells.

Challen GA, Goodell MA.

Exp Hematol. 2010 May;38(5):403-16. doi: 10.1016/j.exphem.2010.02.011. Epub 2010 Mar 3.

5.

AML1/RUNX1 point mutation possibly promotes leukemic transformation in myeloproliferative neoplasms.

Ding Y, Harada Y, Imagawa J, Kimura A, Harada H.

Blood. 2009 Dec 10;114(25):5201-5. doi: 10.1182/blood-2009-06-223982. Epub .

6.

Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics.

Heinrichs S, Kulkarni RV, Bueso-Ramos CE, Levine RL, Loh ML, Li C, Neuberg D, Kornblau SM, Issa JP, Gilliland DG, Garcia-Manero G, Kantarjian HM, Estey EH, Look AT.

Leukemia. 2009 Sep;23(9):1605-13. doi: 10.1038/leu.2009.82. Epub 2009 Apr 23.

7.

Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21.

Lyle R, Béna F, Gagos S, Gehrig C, Lopez G, Schinzel A, Lespinasse J, Bottani A, Dahoun S, Taine L, Doco-Fenzy M, Cornillet-Lefèbvre P, Pelet A, Lyonnet S, Toutain A, Colleaux L, Horst J, Kennerknecht I, Wakamatsu N, Descartes M, Franklin JC, Florentin-Arar L, Kitsiou S, Aït Yahya-Graison E, Costantine M, Sinet PM, Delabar JM, Antonarakis SE.

Eur J Hum Genet. 2009 Apr;17(4):454-66. doi: 10.1038/ejhg.2008.214. Epub 2008 Nov 12.

8.

DNA profiling analysis of 100 consecutive de novo acute myeloid leukemia cases reveals patterns of genomic instability that affect all cytogenetic risk groups.

Suela J, Alvarez S, Cifuentes F, Largo C, Ferreira BI, Blesa D, Ardanaz M, García R, Marquez JA, Odero MD, Calasanz MJ, Cigudosa JC.

Leukemia. 2007 Jun;21(6):1224-31. Epub 2007 Mar 22.

PMID:
17377590
9.

The RUNX genes: gain or loss of function in cancer.

Blyth K, Cameron ER, Neil JC.

Nat Rev Cancer. 2005 May;5(5):376-87. Review.

PMID:
15864279
10.

Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions.

Ghozi MC, Bernstein Y, Negreanu V, Levanon D, Groner Y.

Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1935-40.

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