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Results: 1 to 20 of 225

1.

Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.

Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G.

J Pharmacol Exp Ther. 2010 Jul;334(1):285-93. doi: 10.1124/jpet.110.165498. Epub 2010 Apr 8.

PMID:
20378717
[PubMed - indexed for MEDLINE]
Free Article
2.

Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway.

Harikumar KB, Sung B, Pandey MK, Guha S, Krishnan S, Aggarwal BB.

Mol Pharmacol. 2010 May;77(5):818-27. doi: 10.1124/mol.109.062760. Epub 2010 Jan 26.

PMID:
20103608
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB.

Kim SM, Lee SY, Cho JS, Son SM, Choi SS, Yun YP, Yoo HS, Yoon do Y, Oh KW, Han SB, Hong JT.

Eur J Pharmacol. 2010 Apr 10;631(1-3):1-9. doi: 10.1016/j.ejphar.2009.12.018. Epub 2010 Jan 6.

PMID:
20056115
[PubMed - indexed for MEDLINE]
4.

Ursolic acid overcomes Bcl-2-mediated resistance to apoptosis in prostate cancer cells involving activation of JNK-induced Bcl-2 phosphorylation and degradation.

Zhang YX, Kong CZ, Wang LH, Li JY, Liu XK, Xu B, Xu CL, Sun YH.

J Cell Biochem. 2010 Mar 1;109(4):764-73. doi: 10.1002/jcb.22455.

PMID:
20052671
[PubMed - indexed for MEDLINE]
5.

Avicin D, a plant triterpenoid, induces cell apoptosis by recruitment of Fas and downstream signaling molecules into lipid rafts.

Xu ZX, Ding T, Haridas V, Connolly F, Gutterman JU.

PLoS One. 2009 Dec 31;4(12):e8532. doi: 10.1371/journal.pone.0008532.

PMID:
20046832
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Effects of ursolic acid on the proliferation and apoptosis of human ovarian cancer cells.

Wang X, Li L, Wang B, Xiang J.

J Huazhong Univ Sci Technolog Med Sci. 2009 Dec;29(6):761-4. doi: 10.1007/s11596-009-0618-y. Epub 2009 Dec 29.

PMID:
20037823
[PubMed - indexed for MEDLINE]
7.

Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid.

Chu R, Zhao X, Griffin C, Staub RE, Shoemaker M, Climent J, Leitman D, Cohen I, Shtivelman E, Fong S.

Int J Cancer. 2010 Sep 1;127(5):1209-19. doi: 10.1002/ijc.25116.

PMID:
20027631
[PubMed - indexed for MEDLINE]
8.

Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines.

Yan SL, Huang CY, Wu ST, Yin MC.

Toxicol In Vitro. 2010 Apr;24(3):842-8. doi: 10.1016/j.tiv.2009.12.008. Epub 2009 Dec 22.

PMID:
20005942
[PubMed - indexed for MEDLINE]
9.

Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells.

Yasuda S, Yogosawa S, Izutani Y, Nakamura Y, Watanabe H, Sakai T.

Mol Nutr Food Res. 2010 Apr;54(4):559-65. doi: 10.1002/mnfr.200900165.

PMID:
19937855
[PubMed - indexed for MEDLINE]
10.

Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells.

Pandey MK, Sung B, Aggarwal BB.

Int J Cancer. 2010 Jul 15;127(2):282-92. doi: 10.1002/ijc.25059.

PMID:
19937797
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Enhancement of chemotherapeutic agent-induced apoptosis by inhibition of NF-kappaB using ursolic acid.

Li Y, Xing D, Chen Q, Chen WR.

Int J Cancer. 2010 Jul 15;127(2):462-73. doi: 10.1002/ijc.25044.

PMID:
19908232
[PubMed - indexed for MEDLINE]
12.

Protective role of betulinic acid on TNF-alpha-induced cell adhesion molecules in vascular endothelial cells.

Yoon JJ, Lee YJ, Kim JS, Kang DG, Lee HS.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):96-101. doi: 10.1016/j.bbrc.2009.11.009. Epub 2009 Nov 5.

PMID:
19896462
[PubMed - indexed for MEDLINE]
13.

Characterization of celastrol to inhibit hsp90 and cdc37 interaction.

Zhang T, Li Y, Yu Y, Zou P, Jiang Y, Sun D.

J Biol Chem. 2009 Dec 18;284(51):35381-9. doi: 10.1074/jbc.M109.051532. Epub .

PMID:
19858214
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells.

Lui VW, Yau DM, Wong EY, Ng YK, Lau CP, Ho Y, Chan JP, Hong B, Ho K, Cheung CS, Tsang CM, Tsao SW, Chan AT.

Carcinogenesis. 2009 Dec;30(12):2085-94. doi: 10.1093/carcin/bgp253. Epub .

PMID:
19843642
[PubMed - indexed for MEDLINE]
Free Article
15.

Estrogen-like activities of saikosaponin-d in vitro: a pilot study.

Wang P, Ren J, Tang J, Zhang D, Li B, Li Y.

Eur J Pharmacol. 2010 Jan 25;626(2-3):159-65. doi: 10.1016/j.ejphar.2009.09.047. Epub 2009 Oct 9.

PMID:
19819234
[PubMed - indexed for MEDLINE]
16.

Inhibitory effect of cucurbitacin E on pancreatic cancer cells growth via STAT3 signaling.

Sun C, Zhang M, Shan X, Zhou X, Yang J, Wang Y, Li-Ling J, Deng Y.

J Cancer Res Clin Oncol. 2010 Apr;136(4):603-10. doi: 10.1007/s00432-009-0698-x. Epub 2009 Oct 9.

PMID:
19816711
[PubMed - indexed for MEDLINE]
17.

Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism.

Deeb D, Gao X, Jiang H, Janic B, Arbab AS, Rojanasakul Y, Dulchavsky SA, Gautam SC.

Biochem Pharmacol. 2010 Feb 1;79(3):350-60. doi: 10.1016/j.bcp.2009.09.006. Epub 2009 Sep 24.

PMID:
19782051
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Anti-inflammatory effects of madecassic acid via the suppression of NF-kappaB pathway in LPS-induced RAW 264.7 macrophage cells.

Won JH, Shin JS, Park HJ, Jung HJ, Koh DJ, Jo BG, Lee JY, Yun K, Lee KT.

Planta Med. 2010 Feb;76(3):251-7. doi: 10.1055/s-0029-1186142. Epub 2009 Sep 11.

PMID:
19774506
[PubMed - indexed for MEDLINE]
19.

Targeting NF-kappa B with a natural triterpenoid alleviates skin inflammation in a mouse model of psoriasis.

Wang H, Syrovets T, Kess D, B├╝chele B, Hainzl H, Lunov O, Weiss JM, Scharffetter-Kochanek K, Simmet T.

J Immunol. 2009 Oct 1;183(7):4755-63. doi: 10.4049/jimmunol.0900521. Epub 2009 Sep 14.

PMID:
19752240
[PubMed - indexed for MEDLINE]
Free Article
20.

Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway.

Shan JZ, Xuan YY, Zheng S, Dong Q, Zhang SZ.

J Zhejiang Univ Sci B. 2009 Sep;10(9):668-74. doi: 10.1631/jzus.B0920149.

PMID:
19735099
[PubMed - indexed for MEDLINE]
Free PMC Article

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