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Results: 1 to 20 of 73

1.

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.

Kim J, Lee JJ, Kim J, Gardner D, Beachy PA.

Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13432-7. doi: 10.1073/pnas.1006822107. Epub 2010 Jul 12.

PMID:
20624968
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Sonic hedgehog in temporal control of somite formation.

Resende TP, Ferreira M, Teillet MA, Tavares AT, Andrade RP, Palmeirim I.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12907-12. doi: 10.1073/pnas.1000979107. Epub 2010 Jul 1.

PMID:
20615943
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis.

Lee EY, Ji H, Ouyang Z, Zhou B, Ma W, Vokes SA, McMahon AP, Wong WH, Scott MP.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9736-41. doi: 10.1073/pnas.1004602107. Epub 2010 May 11.

PMID:
20460306
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The primary cilium: a signalling centre during vertebrate development.

Goetz SC, Anderson KV.

Nat Rev Genet. 2010 May;11(5):331-44. doi: 10.1038/nrg2774. Review.

PMID:
20395968
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.

Humke EW, Dorn KV, Milenkovic L, Scott MP, Rohatgi R.

Genes Dev. 2010 Apr 1;24(7):670-82. doi: 10.1101/gad.1902910.

PMID:
20360384
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.

Wen X, Lai CK, Evangelista M, Hongo JA, de Sauvage FJ, Scales SJ.

Mol Cell Biol. 2010 Apr;30(8):1910-22. doi: 10.1128/MCB.01089-09. Epub 2010 Feb 12.

PMID:
20154143
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback.

Ribes V, Briscoe J.

Cold Spring Harb Perspect Biol. 2009 Aug;1(2):a002014. doi: 10.1101/cshperspect.a002014. Review.

PMID:
20066087
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus.

Kim J, Kato M, Beachy PA.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21666-71. doi: 10.1073/pnas.0912180106. Epub 2009 Dec 8.

PMID:
19996169
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing.

Parra LM, Zou Y.

Nat Neurosci. 2010 Jan;13(1):29-35. doi: 10.1038/nn.2457. Epub 2009 Nov 29.

PMID:
19946319
[PubMed - indexed for MEDLINE]
10.

Towards an integrated view of Wnt signaling in development.

van Amerongen R, Nusse R.

Development. 2009 Oct;136(19):3205-14. doi: 10.1242/dev.033910. Review.

PMID:
19736321
[PubMed - indexed for MEDLINE]
Free Article
11.

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.

Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT.

Genes Dev. 2009 Aug 15;23(16):1910-28. doi: 10.1101/gad.1794109.

PMID:
19684112
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade.

Hyman JM, Firestone AJ, Heine VM, Zhao Y, Ocasio CA, Han K, Sun M, Rack PG, Sinha S, Wu JJ, Solow-Cordero DE, Jiang J, Rowitch DH, Chen JK.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14132-7. doi: 10.1073/pnas.0907134106. Epub 2009 Aug 5.

PMID:
19666565
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Hedgehog signal transduction by Smoothened: pharmacologic evidence for a 2-step activation process.

Rohatgi R, Milenkovic L, Corcoran RB, Scott MP.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3196-201. doi: 10.1073/pnas.0813373106. Epub 2009 Feb 13.

PMID:
19218434
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.

Valdembri D, Caswell PT, Anderson KI, Schwarz JP, König I, Astanina E, Caccavari F, Norman JC, Humphries MJ, Bussolino F, Serini G.

PLoS Biol. 2009 Jan 27;7(1):e25. doi: 10.1371/journal.pbio.1000025.

PMID:
19175293
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1.

Prahst C, Héroult M, Lanahan AA, Uziel N, Kessler O, Shraga-Heled N, Simons M, Neufeld G, Augustin HG.

J Biol Chem. 2008 Sep 12;283(37):25110-4. doi: 10.1074/jbc.C800137200. Epub 2008 Jul 15.

PMID:
18628209
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.

Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis.

Geretti E, Shimizu A, Klagsbrun M.

Angiogenesis. 2008;11(1):31-9. doi: 10.1007/s10456-008-9097-1. Epub 2008 Feb 19. Review.

PMID:
18283547
[PubMed - indexed for MEDLINE]
18.

High-resolution in situ hybridization to whole-mount zebrafish embryos.

Thisse C, Thisse B.

Nat Protoc. 2008;3(1):59-69. doi: 10.1038/nprot.2007.514.

PMID:
18193022
[PubMed - indexed for MEDLINE]
19.

Patching the gaps in Hedgehog signalling.

Rohatgi R, Scott MP.

Nat Cell Biol. 2007 Sep;9(9):1005-9.

PMID:
17762891
[PubMed - indexed for MEDLINE]
20.

Patched1 regulates hedgehog signaling at the primary cilium.

Rohatgi R, Milenkovic L, Scott MP.

Science. 2007 Jul 20;317(5836):372-6.

PMID:
17641202
[PubMed - indexed for MEDLINE]
Free Article

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