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Items: 1 to 20 of 133

1.

Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction.

Grati M, Kachar B.

Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11476-81. doi: 10.1073/pnas.1104161108. Epub 2011 Jun 27.

2.

Prestin-driven cochlear amplification is not limited by the outer hair cell membrane time constant.

Johnson SL, Beurg M, Marcotti W, Fettiplace R.

Neuron. 2011 Jun 23;70(6):1143-54. doi: 10.1016/j.neuron.2011.04.024.

3.

Forces between clustered stereocilia minimize friction in the ear on a subnanometre scale.

Kozlov AS, Baumgart J, Risler T, Versteegh CP, Hudspeth AJ.

Nature. 2011 May 22;474(7351):376-9. doi: 10.1038/nature10073.

4.

Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.

Zampini V, Rüttiger L, Johnson SL, Franz C, Furness DN, Waldhaus J, Xiong H, Hackney CM, Holley MC, Offenhauser N, Di Fiore PP, Knipper M, Masetto S, Marcotti W.

PLoS Biol. 2011 Apr;9(4):e1001048. doi: 10.1371/journal.pbio.1001048. Epub 2011 Apr 19.

5.

Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.

Caberlotto E, Michel V, Foucher I, Bahloul A, Goodyear RJ, Pepermans E, Michalski N, Perfettini I, Alegria-Prévot O, Chardenoux S, Do Cruzeiro M, Hardelin JP, Richardson GP, Avan P, Weil D, Petit C.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5825-30. doi: 10.1073/pnas.1017114108. Epub 2011 Mar 21.

6.

Gipc3 mutations associated with audiogenic seizures and sensorineural hearing loss in mouse and human.

Charizopoulou N, Lelli A, Schraders M, Ray K, Hildebrand MS, Ramesh A, Srisailapathy CR, Oostrik J, Admiraal RJ, Neely HR, Latoche JR, Smith RJ, Northup JK, Kremer H, Holt JR, Noben-Trauth K.

Nat Commun. 2011 Feb 15;2:201. doi: 10.1038/ncomms1200.

7.

Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8.

Manor U, Disanza A, Grati M, Andrade L, Lin H, Di Fiore PP, Scita G, Kachar B.

Curr Biol. 2011 Jan 25;21(2):167-72. doi: 10.1016/j.cub.2010.12.046. Epub 2011 Jan 13.

8.

Genetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in mice.

Jörs S, Grimm C, Becker L, Heller S.

PLoS One. 2010 Dec 13;5(12):e14317. doi: 10.1371/journal.pone.0014317.

9.

Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.

Verpy E, Leibovici M, Michalski N, Goodyear RJ, Houdon C, Weil D, Richardson GP, Petit C.

J Comp Neurol. 2011 Feb 1;519(2):194-210. doi: 10.1002/cne.22509.

10.

A mouse model for human hearing loss DFNB30 due to loss of function of myosin IIIA.

Walsh VL, Raviv D, Dror AA, Shahin H, Walsh T, Kanaan MN, Avraham KB, King MC.

Mamm Genome. 2011 Apr;22(3-4):170-7. doi: 10.1007/s00335-010-9310-6. Epub 2010 Dec 17.

PMID:
21165622
11.

Mechanosensitive channels in microbes.

Kung C, Martinac B, Sukharev S.

Annu Rev Microbiol. 2010;64:313-29. doi: 10.1146/annurev.micro.112408.134106. Review.

PMID:
20825352
12.

Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.

Coste B, Mathur J, Schmidt M, Earley TJ, Ranade S, Petrus MJ, Dubin AE, Patapoutian A.

Science. 2010 Oct 1;330(6000):55-60. doi: 10.1126/science.1193270. Epub 2010 Sep 2.

13.

Acid-sensing ion channels (ASICs): pharmacology and implication in pain.

Deval E, Gasull X, Noël J, Salinas M, Baron A, Diochot S, Lingueglia E.

Pharmacol Ther. 2010 Dec;128(3):549-58. doi: 10.1016/j.pharmthera.2010.08.006. Epub 2010 Aug 31. Review.

PMID:
20807551
14.

Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.

Lelli A, Kazmierczak P, Kawashima Y, Müller U, Holt JR.

J Neurosci. 2010 Aug 25;30(34):11259-69. doi: 10.1523/JNEUROSCI.1949-10.2010.

15.

The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.

Shin JB, Longo-Guess CM, Gagnon LH, Saylor KW, Dumont RA, Spinelli KJ, Pagana JM, Wilmarth PA, David LL, Gillespie PG, Johnson KR.

J Neurosci. 2010 Jul 21;30(29):9683-94. doi: 10.1523/JNEUROSCI.1541-10.2010.

16.

Adaptive behavior of bacterial mechanosensitive channels is coupled to membrane mechanics.

Belyy V, Kamaraju K, Akitake B, Anishkin A, Sukharev S.

J Gen Physiol. 2010 Jun;135(6):641-52. doi: 10.1085/jgp.200910371.

17.

Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing.

Kitajiri S, Sakamoto T, Belyantseva IA, Goodyear RJ, Stepanyan R, Fujiwara I, Bird JE, Riazuddin S, Riazuddin S, Ahmed ZM, Hinshaw JE, Sellers J, Bartles JR, Hammer JA 3rd, Richardson GP, Griffith AJ, Frolenkov GI, Friedman TB.

Cell. 2010 May 28;141(5):786-98. doi: 10.1016/j.cell.2010.03.049.

18.

Mechanosensitive gating of CFTR.

Zhang WK, Wang D, Duan Y, Loy MM, Chan HC, Huang P.

Nat Cell Biol. 2010 May;12(5):507-12. doi: 10.1038/ncb2053. Epub 2010 Apr 18. Erratum in: Nat Cell Biol. 2010 Aug;12(8):812. Nat Cell Biol. 2010 Jul;12(7):727.

PMID:
20400957
19.

Structural determinants of cadherin-23 function in hearing and deafness.

Sotomayor M, Weihofen WA, Gaudet R, Corey DP.

Neuron. 2010 Apr 15;66(1):85-100. doi: 10.1016/j.neuron.2010.03.028.

20.

Eukaryotic mechanosensitive channels.

Arnadóttir J, Chalfie M.

Annu Rev Biophys. 2010;39:111-37. doi: 10.1146/annurev.biophys.37.032807.125836. Review.

PMID:
20192782
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