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L1 retrotransposition in neurons is modulated by MeCP2.

Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, Gage FH.

Nature. 2010 Nov 18;468(7322):443-6. doi: 10.1038/nature09544.


Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells.

Garcia-Perez JL, Morell M, Scheys JO, Kulpa DA, Morell S, Carter CC, Hammer GD, Collins KL, O'Shea KS, Menendez P, Moran JV.

Nature. 2010 Aug 5;466(7307):769-73. doi: 10.1038/nature09209.


Natural mutagenesis of human genomes by endogenous retrotransposons.

Iskow RC, McCabe MT, Mills RE, Torene S, Pittard WS, Neuwald AF, Van Meir EG, Vertino PM, Devine SE.

Cell. 2010 Jun 25;141(7):1253-61. doi: 10.1016/j.cell.2010.05.020.


Mobile interspersed repeats are major structural variants in the human genome.

Huang CR, Schneider AM, Lu Y, Niranjan T, Shen P, Robinson MA, Steranka JP, Valle D, Civin CI, Wang T, Wheelan SJ, Ji H, Boeke JD, Burns KH.

Cell. 2010 Jun 25;141(7):1171-82. doi: 10.1016/j.cell.2010.05.026.


LINE-1 retrotransposition activity in human genomes.

Beck CR, Collier P, Macfarlane C, Malig M, Kidd JM, Eichler EE, Badge RM, Moran JV.

Cell. 2010 Jun 25;141(7):1159-70. doi: 10.1016/j.cell.2010.05.021.


RNA as the substrate for epigenome-environment interactions: RNA guidance of epigenetic processes and the expansion of RNA editing in animals underpins development, phenotypic plasticity, learning, and cognition.

Mattick JS.

Bioessays. 2010 Jul;32(7):548-52. doi: 10.1002/bies.201000028. No abstract available. Erratum in: Bioessays. 2010 Jul;32(7):642.


High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes.

Ewing AD, Kazazian HH Jr.

Genome Res. 2010 Sep;20(9):1262-70. doi: 10.1101/gr.106419.110. Epub 2010 May 20.


LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?

Singer T, McConnell MJ, Marchetto MC, Coufal NG, Gage FH.

Trends Neurosci. 2010 Aug;33(8):345-54. doi: 10.1016/j.tins.2010.04.001. Epub 2010 May 12.


Somatic expression of LINE-1 elements in human tissues.

Belancio VP, Roy-Engel AM, Pochampally RR, Deininger P.

Nucleic Acids Res. 2010 Jul;38(12):3909-22. doi: 10.1093/nar/gkq132. Epub 2010 Mar 9.


The impact of retrotransposons on human genome evolution.

Cordaux R, Batzer MA.

Nat Rev Genet. 2009 Oct;10(10):691-703. doi: 10.1038/nrg2640. Review.


L1 retrotransposition in human neural progenitor cells.

Coufal NG, Garcia-Perez JL, Peng GE, Yeo GW, Mu Y, Lovci MT, Morell M, O'Shea KS, Moran JV, Gage FH.

Nature. 2009 Aug 27;460(7259):1127-31. doi: 10.1038/nature08248. Epub 2009 Aug 5.


L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism.

Kano H, Godoy I, Courtney C, Vetter MR, Gerton GL, Ostertag EM, Kazazian HH Jr.

Genes Dev. 2009 Jun 1;23(11):1303-12. doi: 10.1101/gad.1803909.


Mobile elements create structural variation: analysis of a complete human genome.

Xing J, Zhang Y, Han K, Salem AH, Sen SK, Huff CD, Zhou Q, Kirkness EF, Levy S, Batzer MA, Jorde LB.

Genome Res. 2009 Sep;19(9):1516-26. doi: 10.1101/gr.091827.109. Epub 2009 May 13.


The regulated retrotransposon transcriptome of mammalian cells.

Faulkner GJ, Kimura Y, Daub CO, Wani S, Plessy C, Irvine KM, Schroder K, Cloonan N, Steptoe AL, Lassmann T, Waki K, Hornig N, Arakawa T, Takahashi H, Kawai J, Forrest AR, Suzuki H, Hayashizaki Y, Hume DA, Orlando V, Grimmond SM, Carninci P.

Nat Genet. 2009 May;41(5):563-71. doi: 10.1038/ng.368. Epub 2009 Apr 19.


Therapeutic application of histone deacetylase inhibitors for central nervous system disorders.

Kazantsev AG, Thompson LM.

Nat Rev Drug Discov. 2008 Oct;7(10):854-68. doi: 10.1038/nrd2681. Review.


Transposable elements and the evolution of regulatory networks.

Feschotte C.

Nat Rev Genet. 2008 May;9(5):397-405. doi: 10.1038/nrg2337. Review.


The story of Rett syndrome: from clinic to neurobiology.

Chahrour M, Zoghbi HY.

Neuron. 2007 Nov 8;56(3):422-37. Review.


L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells.

Yang N, Kazazian HH Jr.

Nat Struct Mol Biol. 2006 Sep;13(9):763-71. Epub 2006 Aug 27.


dbRIP: a highly integrated database of retrotransposon insertion polymorphisms in humans.

Wang J, Song L, Grover D, Azrak S, Batzer MA, Liang P.

Hum Mutat. 2006 Apr;27(4):323-9.


Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition.

Muotri AR, Chu VT, Marchetto MC, Deng W, Moran JV, Gage FH.

Nature. 2005 Jun 16;435(7044):903-10.

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